The European hedgehog (Erinaceus europaeus) – A suitable reservoir for variants of Anaplasma phagocytophilum?

Alberdi, 1998, Natural prevalence of infection with Ehrlichia (Cytoecetes) phagocytophila of Ixodes ricinus ticks in Scotland, Vet. Parasitol., 78, 203, 10.1016/S0304-4017(98)00138-1 Alberdi, 2000, Field evidence that roe deer (Capreolus capreolus) are a natural host for Ehrlichia phagocytophila, Epidemiol. Infect., 124, 315, 10.1017/S0950268899003684 Arthur, 1963 Beck, 2005, Flohbekämpfung bei wildlebenden und in menschlicher Obhut gepflegten Igeln – ein Therapieansatz mit Nitenpyram (Capstar®), Prakt. Tierarzt, 86, 798 Bown, 2003, Seasonal dynamics of Anaplasma phagocytophila in a rodent-tick (Ixodes trianguliceps) system, United Kingdom, Emerg. Infect. Dis., 9, 63, 10.3201/eid0901.020169 Bown, 2006, Sympatric Ixodes trianguliceps and Ixodes ricinus ticks feeding on field voles (Microtus agrestis): potential for increased risk of Anaplasma phagocytophilum in the United Kingdom?, Vector Borne Zoonotic Dis., 6, 404, 10.1089/vbz.2006.6.404 Bown, 2011, The common shrew (Sorex araneus): a neglected host of tick-borne infections?, Vector Borne Zoonotic Dis., 11, 947, 10.1089/vbz.2010.0185 Courtney, 2004, Multiplex real-time PCR for detection of Anaplasma phagocytophilum and Borrelia burgdorferi, J. Clin. Microbiol., 42, 3164, 10.1128/JCM.42.7.3164-3168.2004 Eckert, J., Friedhoff, K.T., Zahner, H., Deplazes, P., 2005. Lehrbuch der Parasitologie für die Tiermedizin. Enke Verlag in MVS Medizinverlag Stuttgart. Egli, R., 2004. Comparison of physical condition and parasite burdens in rural, suburban and urban hedgehogs Erinaceus europaeus: implications for conservation. Diploma thesis. University of Bern, Switzerland, Bern. Estrada-Peña, 2001, Distribution, abundance, and habitat preferences of Ixodes ricinus (Acari: Ixodidae) in northern Spain, J. Med. Entomol., 38, 361, 10.1603/0022-2585-38.3.361 Franzén, 2009, Molecular evidence for persistence of Anaplasma phagocytophilum in the absence of clinical abnormalities in horses after recovery from acute experimental infection, J. Vet. Intern. Med., 23, 636, 10.1111/j.1939-1676.2009.0317.x Goethert, 2003, Enzootic transmission of the agent of human granulocytic ehrlichiosis among cottontail rabbits, Am. J. Trop. Med. Hyg., 68, 633, 10.4269/ajtmh.2003.68.633 Granquist, 2010, Variant- and individual dependent nature of persistent Anaplasma phagocytophilum infection, Acta Vet. Scand., 52, 25, 10.1186/1751-0147-52-25 Hartelt, 2004, Pathogens and symbionts in ticks: prevalence of Anaplasma phagocytophilum (Ehrlichia sp.), Wolbachia sp., Rickettsia sp., and Babesia sp. in Southern Germany, Int. J. Med. Microbiol., 293, 86 Kauffmann, 2011, Anaplasma phagocytophilum and Babesia spp. in wild ungulates in Germany, 98 Labuda, 1999, Survival strategy of tick-borne encephalitis virus: cellular basis and environmental determinants, Zentralbl. Bakteriol., 289, 513, 10.1016/S0934-8840(99)80005-X Leonhard, S., 2005. Untersuchungen zur Häufigkeit von Borrelia burgdorferi sensu lato, Anaplasma phagocytophilum and Babesia spp. in Ixodes ricinus aus Bayern und Baden-Württemberg. Doctoral thesis. Ludwig-Maximilians-Universität, Munich, Germany. Liebisch, 1986, Ticks of domestic and wild animals in Germany: on the occurrence and biology of the hedgehog tick (Ixodes hexagonus) and the fox tick (Ixodes canisuga), Dtsch. Tierärztl. Wochenschr., 93, 447 Liebisch, 1985, Zum Befall von Hunden und Katzen mit Zecken und Flöhen in Deutschland, Prakt. Tierarzt, 66, 817 Mantelli, 2006, Prevalence of Borrelia burgdorferi s.l. and Anaplasma phagocytophilum in the wood tick Ixodes ricinus in the Province of Trento, Italy, Eur. J. Clin. Microbiol. Infect. Dis., 25, 737, 10.1007/s10096-006-0208-x Massung, 1998, Nested PCR assay for detection of granulocytic ehrlichiae, J. Clin. Microbiol., 36, 1090, 10.1128/JCM.36.4.1090-1095.1998 Maurer, M., 2008. Der Einfluss von Schildzecken (Ixodes ricinus und Ixodes hexagonus) auf die Fitness des Europäischen Igels Erinaceus europaeus. Diploma thesis. University of Karlsruhe, Karlsruhe, Germany. Nijhof, 2007, Ticks and associated pathogens collected from domestic animals in the Netherlands, Vector Borne Zoonotic Dis., 7, 585, 10.1089/vbz.2007.0130 Petrovec, 2002, Infection with Anaplasma phagocytophila in cervids from Slovenia: evidence of two genotypic lineages, Wiener Klin. Wochenschr., 114, 641 Pfäffle, M., 2010. Influence of parasites on fitness parameters of the European hedgehog (Erinaceus europaeus). Doctoral thesis. Karlsruher Institut für Technologie – Universitätsbereich, Karlsruhe, Germany. Pfäffle, 2009, Tick-induced blood loss leads to regenerative anaemia in the European hedgehog (Erinaceus europaeus), Parasitology, 136, 443, 10.1017/S0031182009005514 Pfäffle, 2011, Comparative population dynamics of a generalist (Ixodes ricinus) and specialist tick (I. hexagonus) species from European hedgehogs, Exp. Appl. Acarol., 54, 151, 10.1007/s10493-011-9432-x Reeve, 1994 Scharf, 2011, Distinct host species correlate with Anaplasma phagocytophilum ankA gene clusters, J. Clin. Microbiol., 49, 790, 10.1128/JCM.02051-10 Schauer, S., 2008. Genetische Charakterisierung von Anaplasma phagocytophilum Stämmen. Doctoral thesis. Albert-Ludwigs-University, Freiburg im Breisgau, Germany. Schex, 2011, Rickettsia spp. in wild small mammals in Lower Bavaria, South-Eastern Germany, Vector Borne Zoonotic Dis., 11, 493, 10.1089/vbz.2010.0060 Schorn, 2011, Prevalence of Anaplasma phagocytophilum in Ixodes ricinus in Bavarian public parks, Germany, Ticks Tick Borne Dis., 2, 196, 10.1016/j.ttbdis.2011.09.009 Scorpio, 2010, Comparative strain analysis of Anaplasma phagocytophilum infection and clinical outcomes in a canine model of granulocytic anaplasmosis, Vector Borne Zoonotic Dis., 11, 223, 10.1089/vbz.2009.0262 Silaghi, 2008, Anaplasma phagocytophilum infection in Ixodes ricinus, Bavaria, Germany, Emerg. Infect. Dis., 14, 972, 10.3201/eid1406.071095 Silaghi, 2011, Genetic variants of Anaplasma phagocytophilum in wild caprine and cervid ungulates from the Alps in Tyrol, Austria, Vector Borne Zoonotic Dis., 11, 355, 10.1089/vbz.2010.0051 Silaghi, 2011, Isolation, propagation and preliminary characterisation of Anaplasma phagocytophilum from roe deer (Capreolus capreolus) in the tick cell line IDE8, Ticks Tick Borne Dis., 2, 204, 10.1016/j.ttbdis.2011.09.002 Silaghi, 2011, Investigations on the relationship of molecular and clinical findings of Anaplasma phagocytophilum involved in natural infections of dogs, J. Clin. Microbiol., 49, 4413, 10.1128/JCM.06041-11 Silaghi, 2011, Genetic variants of Anaplasma phagocytophilum from 14 equine granulocytic anaplasmosis cases, Parasites and Vectors, 4, 161, 10.1186/1756-3305-4-161 Silaghi, 2011, PCR detection of Anaplasma phagocytophilum in goat flocks in an area endemic for tick-borne fever in Switzerland, Parasite, 18, 57, 10.1051/parasite/2011181057 Skuballa, 2007, European hedgehogs as hosts for Borrelia spp., Germany, Emerg. Infect. Dis., 13, 952, 10.3201/eid1306.070224 Skuballa, 2010, Molecular detection of Anaplasma phagocytophilum in the European hedgehog (Erinaceus europaeus) and its ticks, Vector Borne Zoonotic Dis., 10, 1055, 10.1089/vbz.2009.0150 Stuen, 2010, Experimental infection in lambs with a red deer (Cervus elaphus) isolate of Anaplasma phagocytophilum, J. Wildl. Dis., 46, 803, 10.7589/0090-3558-46.3.803 von Loewenich, 2003, High diversity of ankA sequences of Anaplasma phagocytophilum among Ixodes ricinus ticks in Germany, J. Clin. Microbiol., 41, 5033, 10.1128/JCM.41.11.5033-5040.2003 Vor, 2010, Tick burden on European roe deer (Capreolus capreolus), Exp. Appl. Acarol., 51, 405, 10.1007/s10493-010-9337-0 Woldehiwet, 2010, The natural history of Anaplasma phagocytophilum, Vet. Parasitol., 167, 108, 10.1016/j.vetpar.2009.09.013 Zeman, 2008, Segregation of genetic variants of Anaplasma phagocytophilum circulating among wild ruminants within a Bohemian forest (Czech Republic), Int. J. Med. Microbiol., 298, 203, 10.1016/j.ijmm.2008.03.003