The Entamoeba histolytica serum-inducible transmembrane kinase EhTMKB1-9 is involved in intestinal amebiasis

Asgharpour, 2005, Resistance to intestinal Entamoeba histolytica infection is conferred by innate immunity and Gr-1+ cells, Infect. Immun., 73, 4522, 10.1128/IAI.73.8.4522-4529.2005 Beck, 2005, Identification and gene expression analysis of a large family of transmembrane kinases related to the Gal/GalNAc lectin in Entamoeba histolytica, Eukaryotic Cell, 4, 722, 10.1128/EC.4.4.722-732.2005 Boettner, 2008, Entamoeba histolytica phagocytosis of human erythrocytes involves PATMK, a member of the transmembrane kinase family, PLoS Pathog., 4, e8, 10.1371/journal.ppat.0040008 Buss, 2010, Members of the Entamoeba histolytica transmembrane kinase family play non-redundant roles in growth and phagocytosis, Int. J. Parasitol., 40, 833, 10.1016/j.ijpara.2009.12.007 Chadee, 1989, Entamoeba histolytica: diffuse liver inflammation in gerbils (Meriones unguiculatus) with experimentally induced amebic liver abscess, J. Protozool., 36, 154, 10.1111/j.1550-7408.1989.tb01064.x Cohen, 2002, Protein kinases – the major drug targets of the twenty-first century?, Nat. Rev. Drug Discov., 1, 309, 10.1038/nrd773 Diamond, 1978, A new medium for the axenic cultivation of Entamoeba histolytica and other Entamoeba, Trans. R. Soc. Trop. Med. Hyg., 72, 431, 10.1016/0035-9203(78)90144-X Doerig, 2002, Protein kinases as drug targets in parasitic protozoa, Trends Parasitol., 18, 366, 10.1016/S1471-4922(02)02321-8 Doerig, 2004, Protein kinases as targets for anti-parasitic chemotherapy, Biochim. Biophys. Acta, 1697, 155, 10.1016/j.bbapap.2003.11.021 Duggal, 2011, A mutation in the leptin receptor is associated with Entamoeba histolytica infection in children, J. Clin. Invest., 121, 1191, 10.1172/JCI45294 Gilchrist, C.A., Moore, E.S., Zhang, Y., Bousquet, C.B., Lannigan, J.A., Mann, B.J., Petri, W.A., 2010. Regulation of virulence of Entamoeba histolytica by the URE3-BP transcription factor. MBio 1. Goldberg, 2006, The dictyostelium kinome-analysis of the protein kinases from a simple model organism, PLoS Genet., 2, e38, 10.1371/journal.pgen.0020038 Grant, 2004, Inhibitors of Leishmania mexicana CRK3 cyclin-dependent kinase: chemical library screen and antileishmanial activity, Antimicrob. Agents Chemother., 48, 3033, 10.1128/AAC.48.8.3033-3042.2004 Guo, 2011, Leptin signaling in intestinal epithelium mediates resistance to enteric infection by Entamoeba histolytica, Mucosal. Immunol., 4, 294, 10.1038/mi.2010.76 Hamann, 1997, Tetracycline-controlled gene expression in Entamoeba histolytica, Mol. Biochem. Parasitol., 84, 83, 10.1016/S0166-6851(96)02771-5 Haque, 2002, Innate and acquired resistance to amebiasis in Bangladeshi children, J. Infect. Dis., 186, 547, 10.1086/341566 Haque, 2003, Amebiasis, N. Engl. J. Med., 348, 1565, 10.1056/NEJMra022710 Hellberg, 2001, Overexpression of cysteine proteinase 2 in Entamoeba histolytica or Entamoeba dispar increases amoeba-induced monolayer destruction in vitro but does not augment amoebic liver abscess formation in gerbils, Cell Microbiol., 3, 13, 10.1046/j.1462-5822.2001.00086.x Houpt, 2002, The mouse model of amebic colitis reveals mouse strain susceptibility to infection and exacerbation of disease by CD4+ T cells, J. Immunol., 169, 4496, 10.4049/jimmunol.169.8.4496 Linggi, 2006, ErbB receptors: new insights on mechanisms and biology, Trends Cell Biol., 16, 649, 10.1016/j.tcb.2006.10.008 Manning, 2008, The protist, Monosiga brevicollis, has a tyrosine kinase signaling network more elaborate and diverse than found in any known metazoan, Proc. Natl. Acad. Sci. USA, 105, 9674, 10.1073/pnas.0801314105 Mehra, 2006, Expression and function of a family of transmembrane kinases from the protozoan parasite Entamoeba histolytica, Infect. Immun., 74, 5341, 10.1128/IAI.00025-06 Mora-Galindo, J., Gutiérrez-Lozano, M., Anaya-Velázquez, F., 1997. Entamoeba histolytica: kinetics of hemolytic activity, erythrophagocytosis and digestion of erythrocytes. Arch. Med. Res. 28 (Spec no.), 200–201. Naula, 2005, Protein kinases as drug targets in trypanosomes and Leishmania, Biochim. Biophys. Acta, 1754, 151, 10.1016/j.bbapap.2005.08.018 Olvera, A., Olvera, F., Vines, R.R., Recillas-Targa, F., Lizardi, P.M., Dhar, S., Bhattacharya, S., Petri, W., Jr., Alagón, A., 1997. Stable transfection of Entamoeba histolytica trophozoites by lipofection. Arch. Med. Res. 28 (Spec no.), 49–51. Parsons, 2005, Comparative analysis of the kinomes of three pathogenic trypanosomatids: Leishmania major, Trypanosoma brucei and Trypanosoma cruzi, BMC Genomics, 6, 127, 10.1186/1471-2164-6-127 Petri, 1987, Isolation of the galactose-binding lectin that mediates the in vitro adherence of Entamoeba histolytica, J. Clin. Invest., 80, 1238, 10.1172/JCI113198 Petri, 2009, Prospective case-control study of the association between common enteric protozoal parasites and diarrhea in Bangladesh, Clin. Infect. Dis., 48, 1191, 10.1086/597580 Pontes, 2002, Detection by polymerase chain reaction of Schistosoma mansoni DNA in human serum and feces, Am. J. Trop. Med. Hyg., 66, 157, 10.4269/ajtmh.2002.66.157 Sahoo, 2004, Calcium binding protein 1 of the protozoan parasite Entamoeba histolytica interacts with actin and is involved in cytoskeleton dynamics, J. Cell. Sci., 117, 3625, 10.1242/jcs.01198 Samuel L, 2003, Amoebiasis, Lancet, 361, 1025, 10.1016/S0140-6736(03)12830-9 Shrimal, 2010, Serum-dependent selective expression of EhTMKB1-9, a member of Entamoeba histolytica B1 family of transmembrane kinases, PLoS Pathog., 6, e1000929, 10.1371/journal.ppat.1000929 Sikorski, 2002, Identification of complex composition, strong strain diversity and directional selection in local Pseudomonas stutzeri populations from marine sediment and soils, Environ. Microbiol., 4, 465, 10.1046/j.1462-2920.2002.00325.x Somlata, 2011, A C2 domain protein kinase initiates phagocytosis in the protozoan parasite Entamoeba histolytica, Nat. Commun., 2, 230, 10.1038/ncomms1199 Stratigopoulos, 2009, Functional consequences of the human leptin receptor (LEPR) Q223R transversion, Obesity (Silver Spring), 17, 126, 10.1038/oby.2008.489 Trissl, 1978, Surface properties of Entamoeba: increased rates of human erythrocyte phagocytosis in pathogenic strains, J. Exp. Med., 148, 1137, 10.1084/jem.148.5.1137 Vieth, 2004, Kinomics-structural biology and chemogenomics of kinase inhibitors and targets, Biochim. Biophys. Acta, 1697, 243, 10.1016/j.bbapap.2003.11.028 Ward, 2004, Protein kinases of the human malaria parasite Plasmodium falciparum: the kinome of a divergent eukaryote, BMC Genomics, 5, 79, 10.1186/1471-2164-5-79 Zhang, 2004, Expression of amoebapores is required for full expression of Entamoeba histolytica virulence in amebic liver abscess but is not necessary for the induction of inflammation or tissue damage in amebic colitis, Infect. Immun., 72, 678, 10.1128/IAI.72.2.678-683.2004