The Effect of Physician and Patient Education When Combined with Vardenafil Treatment in Canadian Males with Erectile Dysfunction: An Open-Label, Factorial-Designed, Cluster-Randomized Clinical Trial

The Journal of Sexual Medicine - Tập 5 - Trang 705-715 - 2008
Gerald Brock1, Serge Carrier2, Pierre Alarie3, Peter Pommerville4, Richard Casey5, Stewart Harris6, Richard Ward7
1University of Western Ontario London, Ontario, Canada
2McGill University Health Centre, Montreal, Quebec, Canada
3Hôpital St.-Luc du CHUM, Montreal, Quebec, Canada
4Can-Med Clinical Research, Inc., Victoria, British Columbia, Canada
5Male Health Centre, Oakville, Ontario, Canada
6Thames Valley Practice Unit, London, Ontario, Canada
7Foothills Medical Centre, Calgary, Alberta, Canada

Tài liệu tham khảo

1993, NIH Consensus Statement, Impotence, JAMA, 270, 83, 10.1001/jama.1993.03510010089036 Auld, 2002, Sexuality and erectile dysfunction: Results of a national survey, J Sex Reprod Med, 2, 50, 10.4172/1488-5069.1000034 Barkin, 2003, Erectile function and male sexual satisfaction: A national survey, J Sex Reprod Med, 3, 10B Assalian, 2003, Erectile dysfunction and depression, J Sex Reprod Med, 3, 6 Alarie, 2003, Erectile dysfunction as a couple issue, J Sex Reprod Med, 2, 9 Tsimtsiou, 2006, Predictors of physicians’ involvement in addressing sexual health issues, J Sex Med, 3, 583, 10.1111/j.1743-6109.2006.00271.x 2002, Erectile dysfunction practice guidelines, Can J Urol, 9, 1583 Montague, 2005, The management of erectile dysfunction: An AUA update, J Urol, 174, 230, 10.1097/01.ju.0000164463.19239.19 Saenz de Tejada, 2001, The phosphodiesterase inhibitory selectivity and the in vitro and in vivo potency of the new PDE5 inhibitor vardenafil, Int J Impot Res, 13, 282, 10.1038/sj.ijir.3900726 Goldstein, 2003, Vardenafil, a new phosphodiesterase type 5 inhibitor, in the treatment of erectile dysfunction in men with diabetes. A multicenter, double-blind, placebo-controlled, fixed-dose study, Diabetes Care, 26, 777, 10.2337/diacare.26.3.777 Brock, 2003, Safety and efficacy of vardenafil for the treatment of men with erectile dysfunction after radical retropubic prostatectomy, J Urol, 170, 1278, 10.1097/01.ju.0000086947.00547.49 Carson, 2004, Erectile response with vardenafil in sildenafil nonresponders: A multicentre, double-blind, 12-week, flexible-dose, placebo-controlled erectile dysfunction clinical trial, BJU Int, 94, 1301, 10.1111/j.1464-410X.2004.05161.x Martin-Morales, 2007, Efficacy of vardenafil and influence on self-esteem and self-confidence in patients with severe erectile dysfunction, J Sex Med, 4, 440, 10.1111/j.1743-6109.2006.00426.x Padma-Nathan, 2007, Vardenafil restores erectile function to normal range in men with erectile dysfunction, J Sex Med, 4, 152, 10.1111/j.1743-6109.2006.00380.x Hackett, 2005, Patient preferences in treatment of erectile dysfunction: The continuing importance of patient education, Clin Cornerstone, 7, 57, 10.1016/S1098-3597(05)80049-3 Soumerai, 1993, A controlled trial of educational outreach to improve blood transfusion practice, JAMA, 270, 961, 10.1001/jama.1993.03510080065033 Soumerai, 1998, Effect of local medical opinion leaders on quality of care for acute myocardial infarction: A randomized controlled trial, JAMA, 279, 1358, 10.1001/jama.279.17.1358 Lomas, 1991, Opinion leaders vs audit and feedback to implement practice guidelines. Delivery after previous cesarean section, JAMA, 265, 2202, 10.1001/jama.1991.03460170056033 McCullough, 2002, Achieving treatment optimization with sildenafil citrate (Viagra®) in patients with erectile dysfunction, Urology, 60, 28, 10.1016/S0090-4295(02)01688-6 Hatzimouratidis, 2006, Treatment strategy for “non-responders” to tadalafil and vardenafil: A real-life study, Eur Urol, 50, 126, 10.1016/j.eururo.2006.02.060 Hatzichristou, 2005, Sildenafil failures may be due to inadequate patient instructions and follow-up: A study on 100 non-responders, Eur Urol, 47, 518, 10.1016/j.eururo.2004.12.005 Gruenwald, 2006, Positive effect of counseling and dose adjustment in patients with erectile dysfunction who failed treatment with sildenafil, Eur Urol, 50, 134, 10.1016/j.eururo.2006.01.042 Rosen, 1997, The International Index of Erectile Function (IIEF): A multidimensional scale for assessment of erectile dysfunction, Urology, 49, 822, 10.1016/S0090-4295(97)00238-0 Althof, 1999, EDITS: Development of questionnaires for evaluating satisfaction with treatments for erectile dysfunction, Urology, 53, 793, 10.1016/S0090-4295(98)00582-2 Mirone, 2005, Flexible-dose vardenafil in a community-based population of men affected by erectile dysfunction: A 12-week open-label, multicenter trial, J Sex Med, 2, 842, 10.1111/j.1743-6109.2005.00138.x Giuliano, 2005, Vardenafil is effective and well-tolerated for treating erectile dysfunction in a broad population of men, irrespective of age, BJU Int, 95, 110, 10.1111/j.1464-410X.2004.05260.x Carrier, 2007, Treatment satisfaction with sildenafil in a Canadian real-life setting. A 6-month prospective observational study of primary care practices, J Sex Med, 4, 1404, 10.1111/j.1743-6109.2007.00555.x