The Contorsbody, an antibody format for agonism: Design, structure, and function

Computational and Structural Biotechnology Journal - Tập 18 - Trang 1210-1220 - 2020
Guy J. Georges1, Stefan Dengl1, Alexander Bujotzek1, Friederike Hesse1, Jens A.A. Fischer1, Achim Gärtner1, Jörg Benz2, Matthias E. Lauer2, Philippe Ringler3, Henning Stahlberg3, Friederike Plath4, Ulrich Brinkmann1, Sabine Imhof-Jung1
1Roche Pharmaceutical Research and Early Development, Large Molecule Research, Roche Innovation Center Munich, Nonnenwald 2, 82377 Penzberg, Germany
2Roche Pharmaceutical Research and Early Development, Chemical Biology, Roche Innovation Center, Basel, Switzerland
3C-CINA, Center for Celullar Imaging and Nano Analytics, University of Basel, Switzerland
4Roche Pharmaceutical Research and Early Development, Pharma Technical Development, Roche Innovation Center, Basel, Switzerland

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