The Cloned Capsaicin Receptor Integrates Multiple Pain-Producing Stimuli

Neuron - Tập 21 Số 3 - Trang 531-543 - 1998
Makoto Tominaga1, Michael J. Caterina2, Annika B. Malmberg3, Tobias A. Rosen2, Heather Gilbert3, Kate Skinner3, Brigitte Raumann2, Allan I. Basbaum3, David Julius2
1Department of Cellular and Molecular Pharmacology, W.M. Keck Foundation Center for Integrative Neuroscience, University of California, San Francisco 94143, USA.
2Department of Cellular and Molecular Pharmacology, W. M. Keck Foundation Center for Integrative, Neuroscience, University of California, San Francisco, California 94143, USA
3Departments of Anatomy and Physiology, W. M. Keck Foundation Center for Integrative, Neuroscience, University of California, San Francisco, California 94143, USA

Tóm tắt

Từ khóa


Tài liệu tham khảo

Acs, 1994, Comparison of [3H]resiniferatoxin binding by the vanilloid (capsaicin) receptor in dorsal root ganglia, spinal cord, dorsal vagal complex, sciatic and vagal nerve and urinary bladder of the rat, Life Sci, 55, 1017, 10.1016/0024-3205(94)00636-9

Acs, 1996, Specific binding of [3H]resiniferatoxin by human and rat preoptic area, locus ceruleus, medial hypoyhalamus, reticular formation and ventral thalamus membrane preparations, Life Sci, 59, 1899, 10.1016/S0024-3205(96)00537-1

Bessou, 1969, Response of cutaneous sensory units with unmyelinated fibers to noxious stimuli, J. Neurophysiol, 32, 1025, 10.1152/jn.1969.32.6.1025

Bevan, S.J., and Docherty, R.J. (1993). Cellular mechanisms of the action of capsaicin. In Capsaicin in the Study of Pain, J. Wood, ed. (London: Academic Press), pp. 27–44.

Bevan, 1994, Protons, Trends Neurosci, 17, 509, 10.1016/0166-2236(94)90149-X

Bevan, 1990, Sensory neuron–specific actions of capsaicin, Trends Pharmacol. Sci, 11, 330, 10.1016/0165-6147(90)90237-3

Bevan, 1991, Protons activate a cation conductance in a subpopulation of rat dorsal root ganglion neurones, J. Physiol, 433, 145, 10.1113/jphysiol.1991.sp018419

Bevan, 1992, Capsazepine, Br. J. Pharmacol, 107, 544, 10.1111/j.1476-5381.1992.tb12781.x

Caterina, 1997, The capsaicin receptor, Nature, 389, 816, 10.1038/39807

Cesare, 1996, A novel heat-activated current in nociceptive neurons and its sensitization by bradykinin, Proc. Natl. Acad. Sci. USA, 93, 15435, 10.1073/pnas.93.26.15435

Devor, 1980, Mapping and plasticity of acid phosphatase afferents in the rat dorsal horn, Brain Res, 190, 17, 10.1016/0006-8993(80)91156-7

Dubner, R., and Basbaum, A.I. (1994). Spinal dorsal horn plasticity following tissue or nerve injury. In Textbook of Pain, P.D. Wall and R. Melzack, eds. (Edinburgh: Churchill Livingstone), pp. 225–241.

Fields, 1987

Fox, 1995, Effects of capsazepine against capsaicin- and proton-evoked excitation of single airway c-fibers and vagus nerve from the guinea pig, Neuroscience, 67, 741, 10.1016/0306-4522(95)00115-Y

Geppetti, 1990, Neurochemical evidence for the activation of the `efferent’ function of capsaicin-sensitive nerves by lowering of the pH in the guinea pig urinary bladder, Neurosci. Lett, 114, 101, 10.1016/0304-3940(90)90435-C

Hammond, 1991, Developmental alterations in nociceptive threshold, immunoreactive calcitonin gene-related peptide and substance P, and fluoride-resistant acid phosphatase in neonatally capsaicin-treated rats, J. Comp. Neurol, 312, 436, 10.1002/cne.903120310

Harlow, 1988

Hille, 1992

Hsu, 1981, A comparative study of the antiperoxidase method and an avidin–biotin complex method for studying polypeptide hormones with radioimmunoassay antibodies, Am. J. Clin. Pathol, 75, 734, 10.1093/ajcp/75.5.734

Jacobus, 1977, Phosphorus nuclear magnetic resonance of perfused working rat hearts, Nature, 265, 756, 10.1038/265756a0

Jancso, 1977, Pharmacologically induced selective degeneration of chemosensitive primary sensory neurons, Nature, 270, 741, 10.1038/270741a0

Kirschstein, 1997, Coexpression of heat-evoked and capsaicin-evoked inward currents in acutely dissociated rat dorsal root ganglion neurons, Neurosci. Lett, 231, 33, 10.1016/S0304-3940(97)00533-8

Konnerth, 1987, Proton-induced transformation of calcium channel in chick dorsal root ganglion cells, J. Physiol, 386, 603, 10.1113/jphysiol.1987.sp016553

Kress, 1996, Low pH facilitates capsaicin responses in isolated sensory neurons of the rat, Neurosci. Lett, 211, 5, 10.1016/0304-3940(96)12691-4

Krishtal, 1980, A receptor for protons in the nerve cell membrane, Neuroscience, 5, 2325, 10.1016/0306-4522(80)90149-9

LaMotte, 1978, Comparison of response of warm and nociceptive c-fiber afferents in monkey with human judgments of thermal pain, J. Neurophysiol, 41, 509, 10.1152/jn.1978.41.2.509

Levine, J., and Taiwo, Y. (1994). Inflammatory pain. In Textbook of Pain, P.D. Wall and R. Melzack, eds. (Edinburgh: Churchill Livingstone), pp. 45–56.

Light, 1979, Re-examination of the dorsal root projection to the spinal dorsal horn including observations on the differential termination of coarse and fine fibers, J. Comp. Neurol, 186, 117, 10.1002/cne.901860202

Liu, 1994, Evidence for presynaptic N-methyl-D-aspartate autoreceptors in the spinal cord dorsal horn, Proc. Natl. Acad. Sci. USA, 91, 8383, 10.1073/pnas.91.18.8383

Liu, 1994, A rapid capsaicin-activated current in rat trigeminal ganglion neurons, Proc. Natl. Acad. Sci. USA, 91, 738, 10.1073/pnas.91.2.738

Liu, 1997, Capsazepine, a vanilloid receptor antagonist, inhibits nicotinic acetylcholine receptors in rat trigeminal ganglia, Neurosci. Lett, 228, 29, 10.1016/S0304-3940(97)00358-3

Llewellyn-Smith, 1992, Complete penetration of antibodies into vibratome sections after glutaraldehyde fixation and ethanol treatment, J. Histochem. Cytochem, 40, 1741, 10.1177/40.11.1431060

Maggi, 1992, Therapeutic potential of capsaicin-like molecules, Life Sci, 51, 1777, 10.1016/0024-3205(92)90047-S

Marfurt, 1981, The central projections of trigeminal primary afferent neurons in the cat as determined by the transganglionic transport of horseradish peroxidase, J. Comp. Neurol, 203, 785, 10.1002/cne.902030414

Martin, 1987, Leukotriene and prostaglandin sensitization of cutaneous high-threshold C- and A-Delta mechanonociceptors in the hairy skin of rat hindlimbs, Neuroscience, 22, 651, 10.1016/0306-4522(87)90360-5

Meyer, 1981, Myelinated nociceptor afferents account for the hyperalgesia that follows a burn to the hand, Science, 213, 1527, 10.1126/science.7280675

Meyer, R.A., Campbell, J.N., and Raja, S. (1994). Peripheral neural mechanisms of nociception. In Textbook of Pain, P.D. Wall and R. Melzack, eds. (Edinburgh: Churchill Livingstone), pp. 13–44.

Molander, 1985, Cutaneous projections from the rat hindlimb foot to the substantia gelatinosa of the spinal cord studied by transganglionic transport of WGA-HRP conjugate, J. Comp. Neurol, 237, 476, 10.1002/cne.902370405

Montell, 1989, Molecular characterization of the Drosophila trp locus, Neuron, 2, 1313, 10.1016/0896-6273(89)90069-X

Morgan, 1981, The distribution of visceral primary afferents from the pelvic nerve to Lissauer’s tract and the spinal gray matter and its relationship to the sacral parasympathetic nucleus, J. Comp. Neurol, 201, 415, 10.1002/cne.902010308

Nagy, 1983, Dose-dependent effects of capsaicin on primary sensory neurons in the neonatal rat, J. Neurosci, 3, 399, 10.1523/JNEUROSCI.03-02-00399.1983

Petersen, 1993, Effect of protons on the inward current evoked by capsaicin in isolated dorsal root ganglion cells, Pain, 54, 37, 10.1016/0304-3959(93)90097-9

Reichling, 1997, Heat transduction in rat sensory neurons by calcium-dependent activation of a cation channel, Proc. Natl. Acad. Sci. USA, 94, 7006, 10.1073/pnas.94.13.7006

Ritter, 1992, Age-related changes in capsaicin-induced degeneration in rat brain, J. Comp. Neurol, 318, 103, 10.1002/cne.903180108

Santicioli, 1993, Effect of capsazepine on the release of calcitonin gene-related peptide-like immunoreactivity (CGRP-LI) induced by low pH, capsaicin and potassium in rat soleus muscle, Br. J. Pharmacol, 110, 609, 10.1111/j.1476-5381.1993.tb13854.x

Snider, 1998, Tackling pain at the source, Neuron, 20, 629, 10.1016/S0896-6273(00)81003-X

Steen, 1993, Sustained graded pain and hyperalgesia from harmless experimental tissue acidosis in human skin, Neurosci. Lett, 154, 113, 10.1016/0304-3940(93)90184-M

Steen, 1992, Protons selectively induce lasting excitation and sensitization to mechanical stimulation of nociceptors in rat skin, in vivo, J. Neurosci, 12, 86, 10.1523/JNEUROSCI.12-01-00086.1992

Stevens, 1991, Hypoxia and inflammatory synovitis, Ann. Rheum. Dis, 50, 124, 10.1136/ard.50.2.124

Stoop, 1997, Different sensitivity to pH of ATP-induced currents at four cloned P2X receptors, J. Neurophysiol, 78, 1837, 10.1152/jn.1997.78.4.1837

Strichartz, 1987, An integrated view of the molecular toxinology of sodium channel gating in excitable cells, Annu. Rev. Neurosci, 10, 237, 10.1146/annurev.ne.10.030187.001321

Szallasi, 1994, The vanilloid (capsaicin) receptor, Gen. Pharmacol, 25, 223, 10.1016/0306-3623(94)90049-3

Szallasi, 1995, Vanilloid (capsaicin) receptors in the rat, Brain Res, 703, 175, 10.1016/0006-8993(95)01094-7

Szolcsanyi, J. (1993). Actions of capsaicin on sensory neurons. In Capsaicin in the Study of Pain, J. Wood, ed. (London: Academic Press), pp. 1–26.

Szolcsanyi, 1988, Selective excitation by capsaicin of mechano-heat sensitive nociceptors in rat skin, Brain Res, 446, 262, 10.1016/0006-8993(88)90885-2

Waldmann, 1997, A proton-gated channel involved in acid sensing, Nature, 386, 173, 10.1038/386173a0

Waldmann, 1997, Molecular cloning of a noninactivating proton-gated Na+ channel specific for sensory neurons, J. Biol. Chem, 272, 20975, 10.1074/jbc.272.34.20975

Winter, 1993, Characterization of resiniferatoxin binding and capsaicin sensitivity in adult rat dorsal root ganglia, Neuroscience, 57, 747, 10.1016/0306-4522(93)90021-7