Nghiên cứu quan sát toàn cầu có tính chất triển vọng ChoCO-W: COVID-19 có làm tăng tỷ lệ viêm túi mật hoại tử không?

Springer Science and Business Media LLC - Tập 17 Số 1
Belinda De Simone1, Fikri M. Abu‐Zidan2, Élie Chouillard1, Salomone Di Saverio3, Massimo Sartelli4, Mauro Podda5, Carlos Augusto Gomes6, Ernest E. Moore7, Susan Moug8, Luca Ansaloni9, Yoram Kluger10, Federico Coccolini11, Aitor Landaluce‐Olavarria12, Begoña Estraviz‐Mateos12, Ana Uriguen-Etxeberria12, Alessio Giordano13, Alfonso Palmieri Luna14, Luz Adriana Hernández Amín14, Adriana María Palmieri Hernández14, Amanda Shabana15, Zakaria Andee Dzulkarnaen16, Muhammad Asyraf Othman16, Mohamad Ikhwan Sani16, Andrea Balla17, Rosa Scaramuzzo17, Pasquale Lepiane17, Andrea Bottari18, Fabio Staderini18, Fabio Cianchi18, Andrea Cavallaro19, Antonio Zanghì19, Alessandro Cappellani19, Roberto Campagnacci20, Angela Maurizi20, Mario Martinotti21, Annamaria Ruggieri21, Asri Che Jusoh22, Karim Abdul Rahman22, Anis Suraya M Zulkifli22, Barbara Petronio23, Belén Matías‐García24, Ana Quiroga‐Valcárcel24, Fernando Mendoza‐Moreno24, Boyko Atanasov25, Fabio Cesare Campanile26, Ilaria Vecchioni26, Luca Cardinali27, Grazia Travaglini27, Elisa Sebastiani27, S. Chooklin28, S.S. Chuklin28, Pasquale Cianci29, Enrico Restini29, Sabino Capuzzolo29, Giuseppe Currò30, Rosalinda Filippo30, Michele Rispoli30, Daniel Aparicio-Sánchez31, Virginia Durán Muñóz-Cruzado31, Sandra Dios Barbeito31, Samir Delibegović32, Amar Kesetovic32, Diego Sasia33, Felice Borghi33, Giorgio Giraudo33, Diego Visconti34, Emanuele Doria34, Mauro Santarelli34, Davide Luppi35, Stefano Bonilauri35, Ugo Grossi36, Giacomo Zanus36, Alberto Sartori37, Giacomo Piatto37, Maurizio De Luca37, Domenico Vita36, Luigi Conti38, Patrizio Capelli38, G Cattaneo38, Athanasios Marinis39, Styliani-Aikaterini Vederaki39, Mehmet Bayrak40, Yasemin Altıntaş41, Mustafa Yener Uzunoğlu42, Iskender Eren Demirbas42, Yüksel Altınel43, Serhat Meriç43, Yunus Emre Aktimur43, Derya Salim Uymaz44, Nail Omarov44, İbrahim Fethi Azamat44, Eftychios Lostoridis45, Eleni‐Aikaterini Nagorni45, Antonio Pujante45, Gabriele Anania46, Cristina Bombardini46, Francesco Bagolini46, Emre Gönüllü47, Barış Mantoğlu47, Recayi Çapoğlu47, Stefano Cappato48, Elena Muzio48, Elif Çolak49, Süleyman Polat49, Zehra Alan Köylü49, Fatih Altıntoprak50, Zülfü Bayhan50, Emrah Akın50, Enrico Andolfi51, Rezart Sulce51, Jae Il Kim52, Sung Won Jung52, Yong Chan Shin52, Octavian Enciu53, Elena Toma53, Fabio Medas5, Gian Luigi Canu5, Federico Cappellacci5, Fabrizio D’Acapito54, Giorgio Ercolani54, Leonardo Solaini54, Francesco Roscio55, Federico Clerici55, Roberta Gelmini56, Francesco Serra56, Elena Rossi56, Francesco Fleres57, Guglielmo Clarizia57, Alessandro Spolini57, Francesco Ferrara58, Gabriela Elisa Nita59, Jlenia Sarnari59, Mahir Gachabayov60, Abakar Abdullaev60, Gaetano Poillucci61, Gian Marco Palini62, Simone Veneroni62, Gianluca Garulli62, Micaela Piccoli63, Gianmaria Casoni Pattacini63, Francesca Pecchini63, Giulio Argenio64, Mariano Fortunato Armellino64, Giuseppe Brisinda65, Tedesco Silvia65, Pietro Fransvea65, Giuseppe Ietto66, Caterina Franchi66, Giulio Carcano66, Gennaro Martines67, Giuseppe Trigiante67, G. Negro67, Gustavo Vega68, Agustín Rodríguez González68, Leonardo María Ojeda68, Gaetano Piccolo69, Andrea Bondurri70, Anna Maffioli70, Claudio Guerci70, Boo Han Sin71, Zamri Zuhdi71, Azlanudin Azman71, Hussam Mousa72, Shadi Al Bahri72, Goran Augustin73, Ivan Romić73, Trpimir Morić73, Ioannis Nikolopoulos74, Jacopo Andreuccetti75, Giusto Pignata75, Rossella D’Alessio75, Jakub Kenig76, Urszula Skorus76, Gustavo Pereira Fraga77, Élcio Shiyoiti Hirano77, Jackson Vinícius de Lima Bertuol78, Arda Işık79, Eray Kurnaz79, Mohammad Sohail Asghar80, Ameer Afzal80, Ali Akbar80, Τaxiarchis Κonstantinos Νikolouzakis81, Konstantinos Lasithiotakis81, Emmanuel Chrysos81, Koray Daş82, Nazmi Özer82, Ahmet Şeker82, Mohamed Ibrahim83, Hytham K. S. Hamid83, Ahmed Babiker83, Konstantinos Bouliaris84, George N. Koukoulis84, Chrysoula-Christina Kolla84, Andrea Lucchi85, Laura Angioletti85, Antonio Taddei86, Laura Fortuna86, Carlotta Agostini86, Leo Licari87, Simona Viola88, Cosimo Callari89, Letizia Laface90, Emmanuele Abate90, Massimiliano Casati90, Alessandro Anastasi91, Giuseppe Canonico91, Linda Gabellini91, Lorenzo Tosi92, Anna Guariniello93, Federico Zanzi93, Lovenish Bains94, L. I. Sydorchuk95, Oksana Iftoda95, Andrii Sydorchuk95, Michele Malerba96, Federico Costanzo96, Raffaele Galleano96, M. Monteleone97, Andrea Costanzi97, Carlo Riva97, Maciej Walędziak98, Andrzej Kwiatkowski98, Łukasz Czyżykowski98, Piotr Major99, Marcin Strzałka99, Maciej Matyja99, Michał Natkaniec99, Maria Rosaria Valenti100, Maria Domenica Pia Di Vita100, Maria Sotiropoulou101, Stylianos Kapiris101, Damien Massalou102, Massimiliano Veroux103, Alessio Volpicelli103, Rossella Gioco103, Matteo Uccelli104, Marta Bonaldi104, Stefano Olmi104, M. Nardi105, Giada Livadoti105, Cristian Meşină106, T Dumitrescu106, Mihai Călin Ciorbagiu106, Michele Ammendola107, Giorgio Ammerata107, Roberto Romano107, Mihail Slavchev108, Evangelos P. Misiakos109, Emmanouil Pikoulis109, Dimitrios Papaconstantinou109, Mohamed Elbahnasawy110, Sherief Abdel-Elsalam111, Daniel Moritz Felsenreich112, Julia Jedamzik, Nikolaos V. Michalopoulos113, Theodoros Sidiropoulos113, Maria Papadoliopoulou113, Nicola Cillara114, Antonello Deserra114, Alessandro Cannavera114, Ionuţ Negoi115, Dimitrios Schizas116, Athanasios Syllaios116, Ilias Vagios116, Stavros Gourgiotis117, Nick Dai117, Rekha Gurung117, Marcus Norrey117, Antonio Pesce118, Carlo V. Feo118, Nicolò Fabbri118, Nikolaos Machairas119, Panagiotis Dorovinis119, Myrto D Keramida119, Francesk Mulita120, Georgios Ioannis Verras120, Michail Vailas120, Ömer Yalkın121, Nidal İflazoğlu121, Direnc Yigit121, Oussama Baraket122, Karim Ayed122, Mohamed Hedi Ghalloussi122, Parmenion Patias123, Georgios Ntokos123, Razrim Rahim124, Miklosh Bala125, Asaf Kedar125, Robert G. Sawyer126, Anna Trinh126, Kelsey Miller126, Ruslan Sydorchuk127, Р. П. Кнут127, O. M. Plehutsa127, Rumeysa Kevser Liman128, Zeynep Özkan128, Saleh Abdel Kader129, Sanjay Gupta130, Monika Gureh130, Sara Saeidi131, Mohsen Aliakbarian131, Amin Dalili131, Tomohisa Shoko132, Mitsuaki Kojima132, Raira Nakamoto132, Semra Demirli Atıcı133, Gizem Kilinc Tuncer133, Tayfun Kaya133, Spiros Delis134, Stefano Rossi135, Biagio Picardi135, Simone Rossi Del Monte135, Tania Triantafyllou136, Dimitrios Theodorou136, Tadeja Pintar137, Jure Salobir137, Dimitrios K. Manatakis138, Nikolaos Tasis138, Vasileios Acheimastos138, Orestis Ioannidis139, Lydia Loutzidou139, Savvas Symeonidis139, Tiago Sá140, Mónica Rocha140, Tommaso Guagni141, D Pantalone141, Gherardo Maltinti141, Vladimir Khokha142, Wafaa Abdel‐Elsalam143, Basma Ghoneim143, José López-Ruiz144, Yasi̇n Kara145, Syaza Putri Zainudin146, Firdaus Hayati146, Nornazirah Azizan146, Victoria Tan Phooi Khei147, Rebecca Choy Xin Yi147, Harivinthan Sellappan147, Zaza Demetrashvili148, Nika Lekiashvili148, Ana Tvaladze148, Caterina Froiio149, Daniele Bernardi149, Luigi Bonavina149, Angeles Gil-Olarte144, Sebastiano Grassia150, Estela Romero-Vargas144, Francesco M. Bianco150, Andrew A. Gumbs1, Agron Dogjani151, Ferdinando Agresta152, Andrey Litvin153, Zsolt J. Balogh154, George Gendrikson153, Costanza Martino155, Dimitrios Damaskos156, Νικόλαος Παραράς157, Andrew W. Kirkpatrick158, Mikhail Kurtenkov153, Felipe Couto Gomes6, Adolfo Pisanu5, Oreste Nardello5, Fabrizio Gambarini21, Hager Aref1, Nicola De Angelis159, Vanni Agnoletti160, Antonio Biondi161, Marco Vacante161, Giulia Griggio161, Roberta Tutino162,163,164,165, Marco Massani162,163,164,165, Giovanni Bisetto166, Savino Occhionorelli167, Dario Andreotti167, Domenico Lacavalla167, Walter L. Biffl168, Fausto Catena160
1Department of Emergency, Digestive and Metabolic Minimally Invasive Surgery, Poissy and Saint Germain en Laye Hospitals, Poissy, France
2The Research Office, College of Medicine and Health Sciences, United Arab Emirates University, Al-Ain, United Arab Emirates., United Arab Emirates University, Al-Ain, UAE
3Department of General Surgery, Santa Maria del Soccorso Hospital, San Benedetto del Tronto, Ascoli Piceno, Italy
4Department of General Surgery, Macerata Hospital, Macerata, Italy
5Department of Surgical Science, University of Cagliari, Cagliari, Italy
6Faculdade de Ciência Médicas e da Saúde de Juiz de Fora, Hospital Universitario Terezinha de Jesus (SUPREMA), Juiz de Fora, Brazil
7Ernest E Moore Shock Trauma Center at Denver Health, Denver, CO, USA
8Department of Surgery, Royal Alexandra Hospital, Paisley and Golden Jubilee National Hospital, University of Glasgow, Glasgow, Scotland
9Department of General Surgery, University Hospital of Pavia, Pavia, Italy
10Department of General Surgery, The Rambam Academic Hospital, Haifa, Israel
11Department of General and Emergency Surgery, University Hospital of Pisa, Pisa, Italy
12Alfredo- Espinosa Urduliz Hospital, Urduliz, Spain
13General Surgery Unit ASL Toscana Centro, Santo Stefano Hospital, Prato, Italy
14Universidad de Sucre, Clínica Santa María, Sincelejo, Colombia
15Emergency Surgery Department, John Radcliffe Hospital, Oxford, UK
16Department of Surgery, School of Medical Sciences and Hospital USM, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia
17UOC of General and Minimally Invasive Surgery, Hospital "San Paolo", Largo Donatori del Sangue 1, 00053, Civitavecchia, Rome, Italy
18SOD Chirurgia dell'Apparato Digerente, AOU Careggi, Florence, Italy
19Department of Surgery, University of Catania, Policlinico "G. Rodolico - San Marco" Hospital, Catania, Italy
20U.O.C. of General Surgery, "Carlo Urbani" Hospital, Jesi, AN, Italy
21Hospital "Istituto Città di Pavia", Pavia, Italy
22Department of General Surgery, Hospital Sultan Ismail Petra, 18000, Kuala Krai, Kelantan, Malaysia
23Chirurgia Generale e Mininvasiva, San Polo Monfalcone, Monfalcone, GO, Italy
24Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Spain
25RIMU, Medical University of Plovdiv, UMHAT Eurohospital, Plovdiv, Bulgaria
26Ospedale San Giovanni Decollato Andosilla – ASL, Civita Castellana, Viterbo, VT, Italy
27UOC Chirurgia Generale, Ospedale "Madonna del Soccorso", San Benedetto del Tronto, AP, Italy
28Lviv Regional Clinical Hospital, Lviv, Ukraine
29Lorenzo Bonomo Hospital, ASL BAT, Andria, Puglia, Italy
30Generall Surgery Unit, Science of Health Department, "Mater Domini" Hospital, University "Magna Graecia" Medical School, Viale Europa, 88100, Germaneto, Catanzaro, Italy
31Emergency Surgery Unit, Hospital Virgen del Rocío, Seville, Spain
32Clinic for Surgery, University Clinical Center Tuzla, Tuzla, Bosnia and Herzegovina
33Santa Croce and Carle Hospital, Cuneo, Italy
34Chirurgia Generale d'Urgenza e PS - AOU Cittá della Salute e della Scienza, Turin, Italy
35General and Emergency Surgery, ASMN IRCCS REGGIO EMILIA, Reggio Emilia, Italy
36Surgery Unit 2, Regional Hospital Treviso, DISCOG, University of Padua, Treviso, Italy
37U.O. Chirurgia Generale e d'Urgenza Ospedale San Valentino, Montebelluna, Treviso, Italy
38Department of Surgery, G. Da Saliceto Hospital, AUSL Piacenza, Piacenza, Italy
39Styliani-Aikaterini Vederaki, Third Department of Surgery, "Tzaneio" General Hospital, Piraeus, Greece
40Mehmet Bayrak, Clinic for Surgery, Private Ortadogu Hospital, Adana, Turkey
41Clinic for Radiology, Private Medline Hospital, Adana, Turkey
42Department of General Surgery, Kestel State Hospital, Bursa, Turkey
43Department of General Surgery, Bagcilar Training and Research Hospital University of Health Science, Istanbul, Turkey
44General Surgery Department, Faculty of Medicine, Koc University, Istanbul, Turkey
451St Department of Surgery, Kavala General Hospital, Kavala, Greece
46UO Chirurgia 1, Dipartimento Chirurgico, Arcispedale Sant'Anna, Azienda Ospedaliero-Universitaria'di Ferrara, Ferrara, Italy
47Sakarya Training and Research Hospital, Sakarya, Turkey.
48Department of General Surgery ASL 4, Lavagna Hospital, Genoa, Italy
49Samsun Training and Research Hospital, University of Samsun, Samsun, Turkey
50Department of General Surgery, Faculty of Medicine, Sakarya University, Serdivan, Turkey
51General and Emergency Surgery Unit, San Donato Hospital, Arezzo, Italy
52Department of Surgery, Inje University Ilsan Paik Hospital, Goyang, South Korea
53Elias University Emergency Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
54General and Oncologic Surgery, Morgagni-Pierantoni Hospital, AUSL Romagna, Via C. Forlanini 34, 47121, Forlì, Italy
55Emergency Surgery, ASST Valle Olona, Busto Arsizio, Italy
56Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine AOU Policlinico Di Modena, Modena, Italy
57UOC General Surgery, Hospital Civil of Sondrio, ASST Valtellina e Alto Lario, Sondrio, Italy
58Department of Surgery, San Carlo Borromeo Hospital, ASST Santi Paolo e Carlo, Milan, Italy
59AUSL Reggio Emilia, Ospedale Sant'Anna, Castelnuovo ne Monti, Reggio Emilia, Italy
60Department of Abdominal Surgery, Vladimir City Emergency Hospital, Vladimir, Russia
61Policlinico Universitario Umberto I, Rome, Italy
62Chirurgia generale e d'urgenza, Ospedale Infermi di Rimini, AUSL Romagna, Rimini, Italy
63Department of General Surgery, Emergencies and New Technologies, Baggiovara Civil Hospital, Modena, Italy
64UOC Chirurgia d'Urgenza, AOU San Giovanni di Dio e Ruggi d'Aragona, Salerno, Italy
65Department of Medical and Surgical Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy
66General, Emergency and Transplant Surgery Department, ASST-Settelaghi and University of Insubria, Varese, Italy
67General Surgery Unit, Azienda Ospedaliero Universitaria Policlinico Bari - Italy, Bari, Italy
68Department of Surgery, Hospital de Clinicas, Universidad Nacional de Asunción, San Lorenzo, Paraguay
69Unit of HepatoBilioPancreatic and Digestive Surgery, Department of Health Sciences, San Paolo Hospital, University of Milan, Via Di Rudinì 8, 20142, Milan, Italy
70Department of General Surgery, Department of Biomedical and Clinical Sciences Luigi Sacco, Luigi Sacco University Hospital, Università degli Studi di Milano, Milan, Italy
71HPB Unit, Department of Surgery, Hospital Canselor Tuanku Muhriz, Kuala Lumpur, Malaysia
72College of Medicine, Tawam Hospital, UAE University, Al-Ain, UAE
73Department of Surgery, University Hospital Centre, Zagreb, Croatia
74Lewisham and Greenwich NHS Trust, London, UK
752nd Department of General Surgery, ASST Spedali Civili of Brescia, Brescia, Italy
76Department of General, Gastrointestinal, Oncologic Surgery and Transplantology, Jagiellonian University Medical College, Kraków, Poland
77Division of Trauma Surgery, School of Medical Sciences, University of Campinas (Unicamp), Campinas, Brazil
78Division of General Surgery, Western Paraná University Hospital (Huop-Unioeste), Cascavel, Brazil
79School of Medicine, Erzincan University, Erzincan, Turkey
80King Edward Medical University, Lahore, Pakistan
81Department of General Surgery, University General Hospital of Heraklion, 71110, Heraklion, Crete, Greece
82Department of General Surgery, Adana City Training and Research Hospital, University of Health Sciences, Adana, Turkey
83Kuwaiti Specialized Hospital, Khartoum, Sudan
84Surgical Department, Koutlimbaneio and Triantafylleio General Hospital of Larissa, Larisa, Greece
85U.O. Chirurgia Generale Ospedale "Ceccarini" Riccione, Riccione, Italy
86Hepatobiliary Surgery, Department of Clinical and Experimental Medicine, University of Florence, AOU Careggi, Florence, Italy
87Department of Surgical, Oncological and Oral Sciences (DICHIRONS), Policlinico P. Giaccone, University of Palermo, Via Liborio Giuffré 5, 90127, Palermo, Italy
88University of Palermo, Palermo, Italy
89Department of Surgery, Buccheri La Ferla Hospital, Via Messina Marine, 197, 90123, Palermo, Italy
90Department of General Surgery, Vittorio Emanuele III Hospital, Carate Brianza - ASST Brianza, Carate Brianza, Italy
91Chirurgia Generale, Ospedale San Giovanni Di Dio, Florence, Italy
92Residency Program in General Surgery, University of Bologna, Bologna, Italy
93Section of Emergency Surgery, Department of Surgery, S.Maria delle Croci Hospital Ravenna, Ravenna, Italy
94Department of Surgery, Maulana Azad Medical College and Nayak Hospital, New Delhi, 110002, India
95Bukovinian State Medical University, Chernivtsi, Ukraine
96Ospedale Santa Corona, ASL 2, Savona, Italy
97Andrea Costanzi, Carlo Riva, O.U. of General Surgery, San Leopoldo Mandic Hospital, Merate, ASST, Lecco, Italy
98Department of General, Oncological, Metabolic and Thoracic Surgery, Military Institute of Medicine, Warsaw, Poland
99Department of General and Emergency Surgery, Faculty of Medicine, Jagiellonian University Medical College, Kraków, Poland
100U.O. General Surgery, Azienda Ospedaliera Universitaria "Policlinico - San Marco", Catania, Italy
1013rd Surgical Department, Evangelismos General Hospital, Athens, Greece
102Department of Emergency Surgery, Centre Hospitalier Universitaire de Nice (CHU de Nice), Université Côte d'Azur, Nice, France
103General Surgery, Azienda Policlinico San Marco, Catania, Italy
104General and Oncological Surgery Department, San Marco Hospital GSD, Zingonia, BG, Italy
105San Giovanni Calibita Hospital- Fondazione Fatebenefratelli, Rome, Italy
106Department of Surgery, Emergency County Hospital of Craiova, Craiova, Romania
107Science of Health Department, Digestive Surgery Unit, "Mater Domini" Hospital, University "Magna Graecia" Medical School, Viale Europa, 88100, Germaneto, Catanzaro, Italy
108Department of General Surgery, University Hospital Eurohospital, Plovdiv, Bulgaria
1093rd Department of Surgery, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece
110Emergency Medicine and Traumatology Department, Tanta University Faculty of Medicine, Tanta, Egypt
111Tropical Medicine and Infectious Diseases, Faculty of Medicine, Tanta University, Tanta, Egypt
112Division of Visceral Surgery, Department of General Surgery, Medical University of Vienna, Vienna, Austria
1134Rd Department of Surgery Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece
114Surgery Department, Santissima Trinità Hospital, Cagliari, Italy
115General Surgery Department, Carol Davila University of Medicine and Pharmacy, Emergency Hospital of Bucharest, Bucharest, Romania
116First Department of Surgery, National and Kapodistrian University of Athens, Laiko General Hospital, 11527, Athens, Greece
117Addenbrooke's Hospital, Cambridge University, Cambridge, UK
118Department of Surgery, Delta Hospital, Azienda USL of Ferrara, University of Ferrara, Ferrara, Italy
1192Nd Department of Propaedeutic Surgery, National and Kapodistrian University of Athens, General Hospital Laiko, Athens, Greece
120Department of Surgery, General University Hospital of Patras, Patras, Greece
121Department of Surgical Oncology and Gastroenterological Surgery, Bursa City Hospital, Bursa, Turkey
122Department of General Surgery, Habib Bougatfa Hospital, University Tunis El Manar, Bizerte, Tunisia
1232nd Department of Surgery, General Hospital of Athens "G.Gennimatas", Athens, Greece
124Department of Surgery, Universiti Sains Islam Malaysia, Nilai, Malaysia
125Department of General Surgery and Trauma, Hadassah Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel
126Western Michigan University School of Medicine, Kalamazoo, USA
127Regional Emergency Hospital, Chernivtsi, Ukraine
128General Surgery Clinic, Elazig Fethi Sekin City Hospital, Elazig, Turkey
129Egypt and NMC Specialty Hospital Al Ain, Ain Shams University, Al-Ain, UAE
130Government Medical College and Hospital, Chandigarh, India
131Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
132Department of Emergency and Critical Care Medicine, Department of Acute Care Surgery Center, Adachi Medical Center, Tokyo Women's Medical University, Tokyo, Japan
133Department of General Surgery, University of Health Sciences Tepecik Training and Research Hospital, İzmir, Turkey
134HPB Unit Konstantopouleio Hospital St Olga, Athens, Greece
135Department of General and Emergency Surgery, San Filippo Neri Hospital, ASL Roma 1, Rome, Italy
136Department of Surgery, Hippocration General Hospital of Athens, University of Athens, Athens, Greece
137Department of Abdominal Surgery, University Medical Center Ljubljana, Ljubljana, Slovenia
138Vasileios Acheimastos, Athens Naval and Veterans Hospital, Athens, Greece
1394Th Department of Surgery, Medical School Aristotle University of Thessaloniki, General Hospital "George Papanikolaou", Thessaloniki, Greece
140General Surgery Department, Centro Hospitalar Do Tâmega e Sousa Penafiel, Penafiel, Portugal
141Department of General Surgery, Careggi University Hospital, Florence, Italy
142Emergency Surgery Department, City Hospital, Mozyr, Belarus
143Anesthesia and Surgical Intensive Care Department, Faculty of Medicine, Kafrelsheikh University, Kafrelsheikh, Egypt
144Angeles Gil-Olarte, Estela Romero-Vargas, Hospital Universitario Virgen Macarena, Seville, Spain
145General Surgery Clinic, Health Sciences University, Kanuni Sultan Süleyman Training and Research Hospital, Istanbul, Turkey
146Faculty of Medicine and Health Sciences, Queen Elisabeth Hospital, Universiti Malaysia Sabah, Kota Kinabalu, Malaysia
147Department of Surgery, Queen Elizabeth Hospital, Universiti Malaysia Sabah, Kota Kinabalu, Malaysia
148N. Kipshidze Central University Hospital, Tbilisi, Georgia
149IRCCS Policlinico San Donato, University of Milan, Milan, Italy
150General Surgery Unit, S. Leonardo Hospital, Castellammare Di Stabia, Naples, Italy
151Department of General Surgery, University Hospital of Tirana, Tirana, Albania
152Department of General Surgery, AULSS2 Trevigiana del Veneto, Ospedale di Vittorio Veneto, Vittorio Veneto, TV, Italy
153Department of Surgical Disciplines, Immanuel Kant Baltic Federal University, Regional Clinical Hospital, Kalingrad, Russia
154Department of Traumatology, John Hunter Hospital and University of Newcastle, Newcastle, NSW, Australia
155Anesthesia and Intensive Care Unit, Umberto I Hospital, AUSL Romagna, Lugo, Italy
156Department of General and Emergency Surgery, Royal Infirmary of Edinburgh, University of Edinburgh, Edinburgh, UK
157Department of General Surgery, Dr. Sulaiman Al Habib Hospital, Alfaisal University, Riyadh, Saudi Arabia
158General, Acute Care, Abdominal Wall Reconstruction, and Trauma Surgery, Foothills Medical Centre, Calgary, AB, Canada
159Unit of Digestive and HPB Surgery, CARE Department, Henri Mondor Hospital and University Paris-Est, Creteil, France
160Department of General and Trauma Surgery, Bufalini Hospital, Cesena, Italy
161Department of General Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy
162Chirurgia 1
163Dipartimento di Discipline Chirurgiche , Oncologiche e Stomatologiche (DI.CHIR.ON.S), Ospedale "Ca'Foncell"
164Palermo, Italy
165Univerità degli studi di Palermo, Treviso
166Dipartimento di Scienze Chirurgiche, Oncologiche e Gastroenterologica (DI.SC.O.G.), Chirurgia 1-Ospedale "Ca Foncello"- Treviso, Università degli Studi di Padova, Padua, Italy
167Department of General Surgery, Arcispedale Sant'Anna-University of Ferrara, Ferrara, Italy
168Department of Emergency and Trauma Surgery, Scripps Clinic Medical Group, La Jolla, CA, USA

Tóm tắt

Tóm tắt Đặt vấn đề Tỷ lệ viêm túi mật hoại tử, một tình trạng có khả năng gây biến chứng nặng nề và có thể dẫn đến tử vong, đã được báo cáo là tăng lên trong thời gian đại dịch COVID-19. Mục tiêu của nghiên cứu ChoCO-W là so sánh các phát hiện lâm sàng và kết quả của viêm túi mật cấp tính ở những bệnh nhân mắc COVID-19 so với những bệnh nhân không mắc bệnh này. Phương pháp Dữ liệu được thu thập theo cách có triển vọng trong 6 tháng (từ 1 tháng 10 năm 2020 đến 30 tháng 4 năm 2021) với việc theo dõi trong 1 tháng. Vào tháng 10 năm 2020, biến thể Delta của virus SARS CoV-2 đã được phân lập lần đầu tiên. Các dữ liệu về nhân khẩu học và lâm sàng đã được phân tích và báo cáo theo hướng dẫn STROBE. Các đặc điểm ban đầu và kết quả lâm sàng của bệnh nhân mắc COVID-19 được so sánh với những bệnh nhân không mắc bệnh này. Kết quả Tổng cộng có 2893 bệnh nhân từ 42 quốc gia, 218 trung tâm đã tham gia, với độ tuổi trung bình là 61,3 (SD: 17,39) năm; 1481 (51%) bệnh nhân là nam giới. Một trăm tám mươi (6,9%) bệnh nhân dương tính với COVID-19, trong khi 2412 (93,1%) âm tính. Các bệnh đồng mắc trước đó như bệnh tim mạch (p < 0.0001), tiểu đường (p < 0.0001), và bệnh phổi tắc nghẽn mạn tính nặng (p = 0.005) có tần suất đáng kể hơn ở nhóm COVID-19. Các dấu hiệu cho thấy độ nghiêm trọng của sốc nhiễm trùng bao gồm ARDS (p < 0.0001), điểm số PIPAS (p < 0.0001), điểm số sepsis WSES (p < 0.0001), qSOFA (p < 0.0001), và phân loại Tokyo về độ nghiêm trọng của viêm túi mật cấp (p < 0.0001) cũng cao hơn đáng kể ở nhóm COVID-19. Nhóm bệnh nhân COVID-19 trải qua biến chứng sau phẫu thuật cao hơn (32,2% so với 11,7%, p < 0.0001), thời gian nằm viện trung bình dài hơn (13,21 so với 6,51 ngày, p < 0.0001), và tỷ lệ tử vong cao hơn (13,4% so với 1,7%, p < 0.0001). Tỷ lệ viêm túi mật hoại tử đã tăng gấp đôi ở nhóm COVID-19 (40,7% so với 22,3%). Độ dày trung bình của thành túi mật cao hơn đáng kể ở nhóm COVID-19 [6,32 (SD: 2,44) mm so với 5,4 (SD: 3,45) mm; p < 0.0001]. Kết luận Tỷ lệ viêm túi mật hoại tử cao hơn ở bệnh nhân COVID so với bệnh nhân không mắc COVID nhập viện cấp cứu vì viêm túi mật cấp. Viêm túi mật hoại tử ở bệnh nhân COVID liên quan đến các biến chứng sau phẫu thuật độ cao Clavien-Dindo, thời gian lưu trú tại bệnh viện kéo dài hơn và tỷ lệ tử vong cao hơn. Tỷ lệ mổ cắt túi mật mở cao hơn ở bệnh nhân COVID so với bệnh nhân không mắc COVID. Khuyến nghị nên hoãn điều trị phẫu thuật ở bệnh nhân COVID, khi có thể, để giảm tỷ lệ biến chứng và tử vong. Nhiễm COVID-19 và viêm túi mật hoại tử không phải là các chống chỉ định tuyệt đối để thực hiện phẫu thuật cắt túi mật nội soi, trong từng trường hợp cụ thể, dưới tay nghề của những chuyên gia.

Từ khóa


Tài liệu tham khảo

Yokoe M, Hata J, Takada T, Strasberg SM, Asbun HJ, Wakabayashi G, et al. Tokyo Guidelines 2018: diagnostic criteria and severity grading of acute cholecystitis (with videos). J Hepatobiliary Pancreat Sci. 2018;25:41–54. https://doi.org/10.1002/jhbp.515.

Pisano M, Allievi N, Gurusamy K, Borzellino G, Cimbanassi S, Boerna D, Coccolini F, Tufo A, Di Martino M, Leung J, Sartelli M, Ceresoli M, Maier RV, Poiasina E, De Angelis N, Magnone S, Fugazzola P, Paolillo C, Coimbra R, Di Saverio S, De Simone B, Weber DG, Sakakushev BE, Lucianetti A, Kirkpatrick AW, Fraga GP, Wani I, Biffl WL, Chiara O, Abu-Zidan F, Moore EE, Leppäniemi A, Kluger Y, Catena F, Ansaloni L. 2020 World Society of Emergency Surgery updated guidelines for the diagnosis and treatment of acute calculus cholecystitis. World J Emerg Surg. 2020;15(1):61. https://doi.org/10.1186/s13017-020-00336-x.

Merriam LT, Kanan SA, Dawes LG, Angelos P, Prystowsky PJB, Renge RV, et al. Gangrenous cholecystitis: analysis of risk factors and experience with laparoscopic cholecystectomy. Surgery. 1999;126(4):680–5.

Weiss CA III, Lakshman TV, Schwartz RW. Current diagnosis and treatment of cholecystitis. Curr Surg. 2002;59(1):51–4.

Rahimli M, Wex C, Wiesmueller F, et al. Laparoscopic cholecystectomy during the COVID-19 pandemic in a tertiary care hospital in Germany: higher rates of acute and gangrenous cholecystitis in elderly patients. BMC Surg. 2022;22:168. https://doi.org/10.1186/s12893-022-01621-z].

Asti E, Lovece A, Bonavina L. Gangrenous cholecystitis during hospitalization for SARS-CoV2 infection. Updates Surg. 2020;72(3):917–9. https://doi.org/10.1007/s13304-020-00814-6.

Bruni A, Garofalo E, Zuccalà V, Currò G, Torti C, Navarra G, De Sarro G, Navalesi P, Longhini F, Ammendola M. Histopathological findings in a COVID-19 patient affected by ischemic gangrenous cholecystitis. World J Emerg Surg. 2020;15(1):43. https://doi.org/10.1186/s13017-020-00320-5.

Bozada-Gutiérrez K, Trejo-Avila M, Chávez-Hernández F, Parraguirre-Martínez S, Valenzuela-Salazar C, Herrera-Esquivel J, Moreno-Portillo M. Surgical treatment of acute cholecystitis in patients with confirmed COVID-19: ten case reports and review of literature. World J Clin Cases. 2022;10(4):1296–310. https://doi.org/10.12998/wjcc.v10.i4.1296.

D’Introno A, Gatti P, Manca G, D’Amuri A, Minniti S, Ciracì E. Acute acalculous cholecystitis as an early manifestation of COVID-19: case report and literature review. Acta Biomed. 2022;93(S1):e2022207. https://doi.org/10.23750/abm.v93iS1.12760.

Martínez Caballero J, González González L, Rodríguez Cuéllar E, Ferrero Herrero E, Pérez Algar C, et al. Multicentre cohort study of acute cholecystitis management during the COVID-19 pandemic. Eur J Trauma Emerg Surg. 2021;47(3):683–92. https://doi.org/10.1007/s00068-021-01631-1.

World Medical Association. World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. JAMA. 2013;310(20):2191–4. https://doi.org/10.1001/jama.2013.281053.

de Simone B, Catena F, Di Saverio S, Sartelli M, Abu-Zidan FM, Podda M, et al. Risk factors for necrotic cholecystitis during the COVID-19 pandemic: the ChoCO-WSES prospective collaborative study’s experience. Turk J Surg. 2021;37(4):387–93.

von Elm E, Altman DG, Egger M, Pocock SJ, Gøtzsche PC, Vandenbroucke JP, STROBE Initiative. The strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies. Lancet. 2007;370(9596):1453–7. https://doi.org/10.1016/S0140-6736(07)61602-X.

Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, et al. The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA. 2016;315(8):801–10. https://doi.org/10.1001/jama.2016.0287].

Sartelli M, Abu-Zidan FM, Labricciosa FM, et al. Physiological parameters for prognosis in abdominal sepsis (PIPAS) study: a WSES observational study. World J Emerg Surg. 2019;14:34. https://doi.org/10.1186/s13017-019-0253-2].

Sartelli M, Abu-Zidan FM, Catena F, et al. Global validation of the WSES sepsis severity score for patients with complicated intra-abdominal infections: a prospective multicentre study (WISS Study). World J Emerg Surg. 2015;10:61. https://doi.org/10.1186/s13017-015-0055-0].

Clavien PA, Barkun J, de Oliveira ML, Vauthey JN, Dindo D, Schulick RD, et al. The Clavien-Dindo classification of surgical complications: five-year experience. Ann Surg. 2009;250(2):187–96. https://doi.org/10.1097/SLA.0b013e3181b13ca2.

Siriwardena AK, CHOLECOVID Collaborative. Global overview of the management of acute cholecystitis during the COVID-19 pandemic (CHOLECOVID study). BJS Open. 2022;6(3):zrac052. https://doi.org/10.1093/bjsopen/zrac052. Erratum in: BJS Open. 2022;6(3).

Önder A, Kapan M, Ülger BV, Oğuz A, Türkoğlu A, Uslukaya Ö. Gangrenous cholecystitis: mortality and risk factors. Int Surg. 2015;100(2):254–60. https://doi.org/10.9738/INTSURG-D-13-00222.1.

Ganapathi AM, Speicher PJ, Englum BR, Perez A, Tyler DS, Zani S. Gangrenous cholecystitis: a contemporary review. J Surg Res. 2015;197:18–24.

Carpenè G, Onorato D, Nocini R, Fortunato G, Rizk JG, Henry BM, Lippi G. Blood lactate concentration in COVID-19: a systematic literature review. Clin Chem Lab Med (CCLM). 2022;60(3):332–7. https://doi.org/10.1515/cclm-2021-1115].

Lucchetta V, Bonvicini D, Ballin A, Tiberio I. Propofol infusion syndrome in severe COVID-19. Br J Anaesth. 2020;125:e441–2. https://doi.org/10.1016/j.bja.2020.08.020.

Kow CS, Hasan SS. Metformin use amid coronavirus disease 2019 pandemic. J Med Virol. 2020;92:2401–2. https://doi.org/10.1002/jmv.26090.

Rizk JG, Forthal DN, Kalantar-Zadeh K, Mehra MR, Lavie CJ, Rizk Y, et al. Expanded access programs, compassionate drug use, and emergency use authorizations during the COVID-19 pandemic. Drug Discov Today. 2021;26:593–603. https://doi.org/10.1016/j.drudis.2020.11.025.

Iepsen UW, Plovsing RR, Tjelle K, Foss NB, Meyhoff CS, Ryrsø CK, Berg RMG, Secher NH. The role of lactate in sepsis and COVID-19: perspective from contracting skeletal muscle metabolism. Exp Physiol. 2022;107(7):665–73. https://doi.org/10.1113/EP089474.

Metawea MI, Yousif WI, Moheb I. COVID 19 and liver: an A-Z literature review. Dig Liver Dis. 2021;53(2):146–52. https://doi.org/10.1016/j.dld.2020.09.010.

Nardo AD, Schneeweiss-Gleixner M, Bakail M, Dixon ED, Lax SF, Trauner M. Pathophysiological mechanisms of liver injury in COVID-19. Liver Int. 2021;41(1):20–32. https://doi.org/10.1111/liv.14730.

Cai Q, Huang D, Yu H, Zhu Z, Xia Z, Su Y, et al. COVID-19: abnormal liver function tests. J Hepatol. 2020;73(3):566–74. https://doi.org/10.1016/j.jhep.2020.04.006.

Wright FL, Vogler TO, Moore EE, et al. Fibrinolysis shutdown correlates to thromboembolic events in severe COVID-19 infection. J Am Coll Surg. 2020;231(2):193–203. https://doi.org/10.1016/j.jamcollsurg.2020.05.007.

Bunch CM, Moore EE, Moore HB, Neal MD, Thomas AV, Zackariya N, Zhao J, Zackariya S, Brenner TJ, Berquist M, Buckner H, Wiarda G, Fulkerson D, Huff W, Kwaan HC, Lankowicz G, Laubscher GJ, Lourens PJ, Pretorius E, Kotze MJ, Moolla MS, Sithole S, Maponga TG, Kell DB, Fox MD, Gillespie L, Khan RZ, Mamczak CN, March R, Macias R, Bull BS, Walsh MM. Immuno-thrombotic complications of COVID-19: implications for timing of surgery and anticoagulation. Front Surg. 2022. https://doi.org/10.3389/fsurg.2022.889999.

Kichloo A, Dettloff K, Aljadah M, Albosta M, Jamal S, Singh J, et al. COVID-19 and hypercoagulability: a review. Clin Appl Thromb Hemost. 2020. https://doi.org/10.1177/1076029620962853.

Terpos E, Ntanasis-Stathopoulos I, Elalamy I, Kastritis E, Sergentanis TN, Politou M, Psaltopoulou T, Gerotziafas G, Dimopoulos MA. Hematological findings and complications of COVID-19. Am J Hematol. 2020;95(7):834–47. https://doi.org/10.1002/ajh.25829.

Lim MS, Mcrae S. COVID-19 and immunothrombosis: pathophysiology and therapeutic implications. Crit Rev Oncol Hematol. 2021;168:103529. ISSN 1040–8428. https://doi.org/10.1016/j.critrevonc.2021.103529.

Tang N, et al. Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia. J Thromb Haemost. 2020;18(4):844–7.

Klok FA, Kruip MJHA, van der Meer NJM, Arbous MS, Gommers DAMPJ, Kant KM, et al. Incidence of thrombotic complications in critically ill ICU patients with COVID-19. Thromb Res. 2020;191:145. https://doi.org/10.1016/j.thromres.2020.04.013.

De Simone B, Chouillard E, Sartelli M, Biffl WL, Di Saverio S, Moore EE, et al. The management of surgical patients in the emergency setting during COVID-19 pandemic: the WSES position paper. World J Emerg Surg. 2021;16(1):14. https://doi.org/10.1186/s13017-021-00349-0.

Di Castelnuovo A, Costanzo S, Antinori A, Berselli N, Blandi L, Bonaccio M, et al. Heparin in COVID-19 patients is associated with reduced in-hospital mortality: the multicenter Italian CORIST study. Thromb Haemost. 2021;121(8):1054–65. https://doi.org/10.1055/a-1347-6070.

Thachil J, et al. ISTH interim guidance on recognition and management of coagulopathy in COVID-19. J Thromb Haemost. 2020;18(5):1023–6.

Jensen KK, Roth NO, Krarup PM, Bardram L. Surgical management of acute cholecystitis in a nationwide Danish cohort. Langenbecks Arch Surg. 2019;404(5):589–97. https://doi.org/10.1007/s00423-019-01802-0.

Livingston EH, Rege RV. A nationwide study of conversion from laparoscopic to open cholecystectomy. Am J Surg. 2004;188(3):205–11. https://doi.org/10.1016/j.amjsurg.2004.06.013.

Shea JA, Healey MJ, Berlin JA, Clarke JR, Malet PF, Staroscik RN, Schwartz JS, Williams SV. Mortality and complications associated with laparoscopic cholecystectomy. A meta-analysis. Ann Surg. 1996;224(5):609–20. https://doi.org/10.1097/00000658-199611000-00005.

Pucher PH, Brunt LM, Davies N, et al. Outcome trends and safety measures after 30 years of laparoscopic cholecystectomy: a systematic review and pooled data analysis. Surg Endosc. 2018;32:2175–83. https://doi.org/10.1007/s00464-017-5974-2.

Mangieri CW, Hendren BP, Strode MA, Bandera BC, Faler BJ. Bile duct injuries (BDI) in the advanced laparoscopic cholecystectomy era. Surg Endosc. 2019;33(3):724–30. https://doi.org/10.1007/s00464-018-6333-7.

Elshaer M, Gravante G, Thomas K, Sorge R, Al-Hamali S, Ebdewi H. Subtotal cholecystectomy for “difficult gallbladders”: systematic review and meta-analysis. JAMA Surg. 2015;150(2):159–68. https://doi.org/10.1001/jamasurg.2014.1219.

COVIDSurg Collaborative. Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study. Lancet. 20204;396(10243):27–38. https://doi.org/10.1016/S0140-6736(20)31182-X. Erratum in: Lancet. 2020.

COVIDSurg Collaborative; GlobalSurg Collaborative. Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study. Anaesthesia. 2021;76(6):748–58. https://doi.org/10.1111/anae.15458.

Somuncu E, Kara Y, Kızılkaya MC, Bozdağ E, Yıldız ZB, Özkan C, et al. Percutaneous cholecystostomy instead of laparoscopy to treat acute cholecystitis during the COVID-19 pandemic period: single center experience. Ulus Travma Acil Cerrahi Derg. 2021;27(1):89–94. https://doi.org/10.14744/tjtes.2020.69804.

Barabino M, Piccolo G, Trizzino A, Fedele V, Ferrari C, Nicastro V, et al. COVID-19 outbreak and acute cholecystitis in a Hub Hospital in Milan: wider indications for percutaneous cholecystostomy. BMC Surg. 2021;21(1):180. https://doi.org/10.1186/s12893-021-01137-y.

De Simone B, Chouillard E, Di Saverio S, Pagani L, Sartelli M, Biffl WL, et al. Emergency surgery during the COVID-19 pandemic: what you need to know for practice. Ann R Coll Surg Engl. 2020;102(5):323–32. https://doi.org/10.1308/rcsann.2020.0097.

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