The Cardiac Troponin I Gene Is Not Associated with Hypertrophic Cardiomyopathy in Patients From Eastern Finland

Bhavsar, 1996, Isolation and characterization of the human cardiac troponin I gene (TNNI3), Genomics, 35, 11, 10.1006/geno.1996.0317 Bonne, 1998, Familial hypertrophic cardiomyopathy: from mutations to functional defects, Circ Res, 83, 580, 10.1161/01.RES.83.6.580 De La Chapelle, 1993, Disease gene mapping in isolated human populations: the example of Finland, J Med Genet, 30, 857, 10.1136/jmg.30.10.857 Flavigny, 1998, Identification of two novel mutations in the ventricular regulatory myosin light chain gene (MYL2) associated with familial and classical forms of hypertrophic cardiomyopathy, J Mol Med, 76, 208, 10.1007/s001090050210 Geisterfer-Lowrance, 1990, A molecular basis for familial hypertrophic cardiomyopathy: a beta cardiac myosin heavy chain gene missense mutation, Cell, 62, 999, 10.1016/0092-8674(90)90274-I Jääskeläinen, 1998, The cardiac β -myosin heavy chain gene is not the predominant gene for hypertrophic cardiomyopathy in the Finnish population, JACC, 32, 1709, 10.1016/S0735-1097(98)00448-3 Kimura, 1997, Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy, Nat Genet, 16, 379, 10.1038/ng0897-379 Marian, 1992, Detection of a new mutation in the beta-myosin heavy chain gene in an individual with hypertrophic cardiomyopathy, J Clin Invest, 90, 2156, 10.1172/JCI116101 McKenna, 1997, Experience from clinical genetics in hypertrophic cardiomyopathy: proposal for new diaÍgnostic criteria in adult members of affected families, Heart, 77, 130, 10.1136/hrt.77.2.130 Miller, 1988, A simple salting out procedure for extracting DNA from human nucleated cells, Nucleic Acids Res, 16, 1215, 10.1093/nar/16.3.1215 Nakajima-Taniguchi, 1995, Novel missense mutation in alpha-tropomyosin gene found in Japanese patients with hypertrophic cardiomyopathy, J Mol Cell Cardiol, 27, 2053, 10.1016/0022-2828(95)90026-8 Niimura, 1998, Mutations in the gene for cardiac myosin-binding protein C and late-onset familial hypertrophic cardiomyopathy, N Engl J Med, 338, 1248, 10.1056/NEJM199804303381802 Orita, 1989, Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms, Proc Natl Acad Sci USA, 86, 2766, 10.1073/pnas.86.8.2766 Poetter, 1996, Mutations in either the essential or regulatory light chains of myosin are associated with a rare myopathy in human heart and skeletal muscle, Nature Genet, 13, 63, 10.1038/ng0596-63 Sahn, 1978, Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements, Circulation, 58, 1072, 10.1161/01.CIR.58.6.1072 Spirito, 1997, The management of hypertrophic cardiomyopathy, N Engl J Med, 336, 775, 10.1056/NEJM199703133361107 Thierfelder, 1994, Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere, Cell, 77, 701, 10.1016/0092-8674(94)90054-X Watkins, 1995, Mutations in the cardiac myosin binding protein-C gene on chromosome 11 cause familial hypertrophic cardiomyopathy, Nature Genet, 11, 434, 10.1038/ng1295-434 Watkins, 1995, Mutations in the genes for cardiac troponin T and alpha-tropomyosin in hypertrophic cardiomyopathy, N Engl J Med, 332, 1058, 10.1056/NEJM199504203321603 Watkins, 1992, Characteristics and prognostic implications of myosin missense mutations in familial hypertrophic cardiomyopathy, N Engl J Med, 326, 1108, 10.1056/NEJM199204233261703