The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

Nature - Tập 483 Số 7391 - Trang 603-607 - 2012
Jordi Barretina1, Giordano Caponigro2, Nicolas Stransky1, K. Venkatesan2, Adam A. Margolin1, Sung Joon Kim3, Christopher J. Wilson2, Joseph Lehár2, Gregory V. Kryukov1, Dmitriy Sonkin2, Anupama Reddy2, Manway Liu2, Lauren Murray1, Michael F. Berger1, John E. Monahan2, Paula Keskula1, Jodi Meltzer2, Adam Korejwa1, Judit Jané‐Valbuena4, Felipa Mapa2, Joseph Thibault3, Eva Bric-Furlong2, Pichai Raman2, Aaron Shipway3, Ingo H. Engels3, Jill Cheng5, Guoying Karen Yu5, Jianjun Yu5, Peter Aspesi2, Melanie de Silva2, Kalpana Jagtap2, Michael D. Jones2, Li Wang2, Charlie Hatton6, Emanuele Palescandolo6, Supriya Gupta1, Scott Mahan1, Carrie Sougnez1, Robert C. Onofrio1, Ted Liefeld1, Laura E. MacConaill6, Wendy Winckler1, Michael Reich1, Nanxin Li3, Jill P. Mesirov1, Stacey Gabriel1, Gad Getz1, Kristin Ardlie1, Vivien W. Chan5, Vic E. Myer2, Barbara L. Weber2, Jeff Porter2, Markus Warmuth2, Peter M. Finan2, Jennifer L. Harris3, Matthew Meyerson6, Todd R. Golub7, Michael Morrissey2, William R. Sellers2, Robert Schlegel2, Levi A. Garraway6
1The Broad Institute of Harvard and MIT, Cambridge, 02142, Massachusetts, USA
2Novartis Institutes for Biomedical Research, Cambridge, 02139, Massachusetts, USA
3Genomics Institute of the Novartis Research Foundation, San Diego, 92121, California, USA
4Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, 02115, Massachusetts, USA
5Novartis Institutes for Biomedical Research, Emeryville, 94608, California, USA
6Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Harvard Medical School, Boston, 02115, Massachusetts, USA
7Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, 02115, Massachusetts, USA

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