The BRCA1 alternative splicing variant Δ14-15 with an in-frame deletion of part of the regulatory serine-containing domain (SCD) impairs the DNA repair capacity in MCF-7 cells

Cellular Signalling - Tập 24 - Trang 1023-1030 - 2012
Jan Sevcik1,2, Martin Falk3, Petra Kleiblova1, Filip Lhota1, Lenka Stefancikova3, Marketa Janatova1, Lenka Weiterova3, Emilie Lukasova3, Stanislav Kozubek3, Petr Pohlreich1, Zdenek Kleibl1
1Institute of Biochemistry and Experimental Oncology, First Faculty of Medicine, Charles University in Prague, U Nemocnice 5, 128 53 Prague 2, Czech Republic
2Prague Burn Centre, Charles University, Third Faculty of Medicine and Teaching Hospital Kralovske Vinohrady, Srobarova 50, 10034 Prague 10, Czech Republic
3Institute of Biophysics, Academy of Sciences of the Czech Republic, Kralovopolska 135, 61265 Brno, Czech Republic

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