Mối Liên Hệ Giữa Những Thay Đổi Trong Việc Sử Dụng Rượu Và Những Thay Đổi Trong Việc Tuân Thủ Liệu Pháp Kháng Virus Và Độ Ức Chế Virus Ở Phụ Nữ Sống Chung Với HIV

Springer Science and Business Media LLC - Tập 21 - Trang 1836-1845 - 2016
Nikita Barai1, Anne Monroe1,2, Catherine Lesko2, Bryan Lau2, Heidi Hutton3, Cui Yang4, Anika Alvanzo1, Mary Elizabeth McCaul3, Geetanjali Chander1,2
1Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, USA
2Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, USA
3Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, USA
4Health, Behavior and Society, Johns Hopkins University Bloomberg School of Public Health, Baltimore, USA

Tóm tắt

Việc sử dụng rượu nặng có tác động tiêu cực đến phụ nữ nhiễm HIV. Chúng tôi đã xem xét mối quan hệ giữa những thay đổi trong việc sử dụng rượu (được đo bằng phương pháp Thời Gian Theo Dõi) và những thay đổi trong việc tuân thủ liệu pháp kháng virus (tỷ lệ sở hữu thuốc) và độ ức chế virus (HIV RNA), được đo trong khoảng thời gian 6 tháng. Trong số những phụ nữ (1) không tuân thủ hoặc không ức chế vi rút và (2) uống rượu binge không thường xuyên hoặc không uống rượu nặng tại thời điểm đầu, việc tăng lượng rượu uống có liên quan đáng kể đến việc giảm khả năng cải thiện tuân thủ hoặc độ ức chế vi rút sau này (OR để trở thành tuân thủ là 0.90 ở những người uống binge không thường xuyên; OR để trở thành ức chế là 0.81 và 0.75 ở những người uống binge không thường xuyên và những người không uống rượu nặng, tương ứng). Các phát hiện của chúng tôi cho thấy rằng đối với những phụ nữ này, việc tăng cường uống rượu có thể là một rào cản trong việc đạt được độ ức chế vi rút. Giải quyết rào cản này bằng cách tích hợp các chiến lược tư vấn rượu tích cực vào chăm sóc HIV thường xuyên có thể là chìa khóa để cải thiện tỷ lệ độ ức chế vi rút trong số các phụ nữ được giữ lại trong chăm sóc HIV.

Từ khóa

#HIV #rượu #tuân thủ liệu pháp kháng virus #độ ức chế vi rút #phụ nữ #sức khỏe cộng đồng

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