The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study

Cell Chemical Biology - Tập 25 Số 1 - Trang 67-77.e3 - 2018
George M. Burslem1, Blake E. Smith1, Ashton C. Lai1, Saul Jaime‐Figueroa1, Daniel McQuaid1, Daniel P. Bondeson1, Momar Toure1, Hanqing Dong2, Yimin Qian2, Jing Wang2, Andrew P. Crew2, John Hines1, Craig M. Crews1,3
1Department of Molecular, Cellular, and Developmental Biology, Yale University, 219 Prospect Street, New Haven, CT, USA
2Arvinas, LLC, 5 Science Park, New Haven, CT, USA
3Departments of Chemistry and Pharmacology, Yale University, New Haven, CT, USA

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