Testosterone administration modulates moral judgments depending on second-to-fourth digit ratio

Psychoneuroendocrinology - Tập 38 - Trang 1362-1369 - 2013
Estrella R. Montoya1, David Terburg1,2, Peter A. Bos1,2, Geert-Jan Will3, Vincent Buskens4, Werner Raub4, Jack van Honk1,2
1Department of Experimental Psychology, Utrecht University, 3584 CS Utrecht, The Netherlands
2Department of Psychiatry, University of Cape Town, Cape Town 7925, South Africa
3Institute of Psychology, Leiden University, 2333 AK Leiden, The Netherlands
4Department of Sociology/ICS, Utrecht University, Utrecht 3584, CS The Netherlands

Tài liệu tham khảo

Biegon, 2010, Unique distribution of aromatase in the human brain: in vivo studies with PET and [N-methyl-11C]vorozole, Synapse, 64, 801, 10.1002/syn.20791 Blair, 2007, The amygdala and ventromedial prefrontal cortex in morality and psychopathy, Trends Cogn. Sci., 11, 387, 10.1016/j.tics.2007.07.003 Bos, 2012, Acute effects of steroid hormones and neuropeptides on human social-emotional behavior: a review of single administration studies, Front. Neuroendocrinol., 33, 17, 10.1016/j.yfrne.2011.01.002 Bos, 2010, Testosterone decreases trust in socially naive humans, Proc. Natl. Acad. Sci. U.S.A., 107, 9991, 10.1073/pnas.0911700107 Breedlove, 2010, Minireview: organizational hypothesis: instances of the fingerpost, Endocrinology, 151, 4116, 10.1210/en.2010-0041 Carney, 2010, Decision making and testosterone: when the ends justify the means, J. Exp. Soc. Psychol., 46, 668, 10.1016/j.jesp.2010.02.003 Ciaramelli, 2007, Selective deficit in personal moral judgment following damage to ventromedial prefrontal cortex, Soc. Cogn. Affect, 2, 84, 10.1093/scan/nsm001 Crockett, 2010, Serotonin selectively influences moral judgment and behavior through effects on harm aversion, Proc. Natl. Acad. Sci. U.S.A., 107, 17433, 10.1073/pnas.1009396107 Eisenegger, 2011, The role of testosterone in social interaction, Trends Cogn. Sci., 15, 263, 10.1016/j.tics.2011.04.008 Eisenegger, 2010, Prejudice and truth about the effect of testosterone on human bargaining behaviour, Nature, 463, 356, 10.1038/nature08711 Eisenegger, 2012, Eisenegger et al. reply, Nature, 485, E5, 10.1038/nature11137 Fumagalli, 2012, Functional and clinical neuroanatomy of morality, Brain, 135, 2006, 10.1093/brain/awr334 Fumagalli, 2010, Brain switches utilitarian behavior: does gender make the difference?, PLoS ONE, 5, e8865, 10.1371/journal.pone.0008865 Gleichgerrcht, 2012, Selective impairment of cognitive empathy for moral judgment in adults with high functioning autism, Soc. Cogn. Affect Greene, 2007, Why are VMPFC patients more utilitarian?. A dual-process theory of moral judgment explains, Trends Cogn. Sci., 11, 322, 10.1016/j.tics.2007.06.004 Greene, 2009, Pushing moral buttons: the interaction between personal force and intention in moral judgment, Cognition, 111, 364, 10.1016/j.cognition.2009.02.001 Greene, 2004, The neural bases of cognitive conflict and control in moral judgment, Neuron, 44, 389, 10.1016/j.neuron.2004.09.027 Greene, 2001, An fMRI investigation of emotional engagement in moral judgment, Science, 293, 2105, 10.1126/science.1062872 Haidt, 2007, The new synthesis in moral psychology, Science, 316, 998, 10.1126/science.1137651 Hermans, 2006, A single administration of testosterone reduces fear-potentiated startle in humans, Biol. Psychiatry, 59, 872, 10.1016/j.biopsych.2005.11.015 Hermans, 2007, Exogenous testosterone attenuates the integrated central stress response in healthy young women, Psychoneuroendocrinology, 32, 1052, 10.1016/j.psyneuen.2007.08.006 Hermans, 2006, Testosterone administration reduces empathetic behavior: a facial mimicry study, Psychoneuroendocrinology, 31, 859, 10.1016/j.psyneuen.2006.04.002 Huebner, 2011, How the source, inevitability and means of bringing about harm interact in folk-moral judgments, Mind Lang., 26, 210, 10.1111/j.1468-0017.2011.01416.x Koenigs, 2012, Utilitarian moral judgment in psychopathy, Soc. Cogn. Affect, 7, 708, 10.1093/scan/nsr048 Koenigs, 2007, Damage to the prefrontal cortex increases utilitarian moral judgements, Nature, 446, 908, 10.1038/nature05631 Lutchmaya, 2004, 2nd to 4th digit ratios, fetal testosterone and estradiol, Early Hum. Dev., 77, 23, 10.1016/j.earlhumdev.2003.12.002 McCall, 2012, The animal and human neuroendocrinology of social cognition, motivation and behavior, Nat. Neurosci., 15, 681, 10.1038/nn.3084 Moll, 2007, Moral judgments, emotions and the utilitarian brain, Trends Cogn. Sci., 11, 319, 10.1016/j.tics.2007.06.001 Moll, 2002, Functional networks in emotional moral and nonmoral social judgments, Neuroimage, 16, 696, 10.1006/nimg.2002.1118 Moll, 2005, The neural basis of human moral cognition, Nat. Rev. Neurosci., 6, 799, 10.1038/nrn1768 Montoya, 2012, Testosterone, cortisol, and serotonin as key regulators of social aggression: a review and theoretical perspective, Motiv. Emotion, 36, 65, 10.1007/s11031-011-9264-3 Moran, 2011, Impaired theory of mind for moral judgment in high-functioning autism, Proc. Natl. Acad. Sci. U.S.A., 108, 2688, 10.1073/pnas.1011734108 Osterlund, 2000, Estrogen receptor beta (ERbeta) messenger ribonucleic acid (mRNA) expression within the human forebrain: distinct distribution pattern to ERalpha mRNA, J. Clin. Endocrinol. Metab., 85, 3840 Pessoa, 2008, On the relationship between emotion and cognition, Nat. Rev. Neurosci., 9, 148, 10.1038/nrn2317 Phoenix, 1968 Reniers, 2012, Moral decision-making, ToM, empathy and the default mode network, Biol. Psychol., 90, 202, 10.1016/j.biopsycho.2012.03.009 Sarachana, 2011, Sex hormones in autism: androgens and estrogens differentially and reciprocally regulate RORA, a novel candidate gene for autism, PLoS ONE, 6, e17116, 10.1371/journal.pone.0017116 Shacham, 1983, A shortened version of the profile of mood states, J. Pers. Assess., 47, 305, 10.1207/s15327752jpa4703_14 Starcke, 2011, Does stress alter everyday moral decision-making?, Psychoneuroendocrinology, 36, 210, 10.1016/j.psyneuen.2010.07.010 Thornton, 2009, Effects of prenatal androgens on rhesus monkeys: a model system to explore the organizational hypothesis in primates, Horm. Behav., 55, 633, 10.1016/j.yhbeh.2009.03.015 Tuiten, 2000, Time course of effects of testosterone administration on sexual arousal in women, Arch. Gen. Psychiatry, 57, 149, 10.1001/archpsyc.57.2.149 van Honk, 2012, New evidence on testosterone and cooperation, Nature, 485, E4, 10.1038/nature11136 van Honk, 2005, Testosterone reduces unconscious fear but not consciously experienced anxiety: implications for the disorders of fear and anxiety, Biol. Psychiatry, 58, 218, 10.1016/j.biopsych.2005.04.003 van Honk, 2011, Testosterone administration impairs cognitive empathy in women depending on second-to-fourth digit ratio, Proc. Natl. Acad. Sci. U.S.A., 108, 3448, 10.1073/pnas.1011891108 van Honk, 2004, Testosterone shifts the balance between sensitivity for punishment and reward in healthy young women, Psychoneuroendocrinology, 29, 937, 10.1016/j.psyneuen.2003.08.007 van Honk, 2011, Further notes on testosterone as a social hormone, Trends Cogn. Sci., 15, 291 van Honk, 2001, A single administration of testosterone induces cardiac accelerative responses to angry faces in healthy young women, Behav. Neurosci., 115, 238, 10.1037/0735-7044.115.1.238 Young, 2007, The neural basis of the interaction between theory of mind and moral judgment, Proc. Natl. Acad. Sci. U.S.A., 104, 8235, 10.1073/pnas.0701408104 Young, 2012, Psychopathy increases perceived moral permissibility of accidents, J. Abnorm. Psychol., 121, 659, 10.1037/a0027489 Youssef, 2012, Stress alters personal moral decision making, Psychoneuroendocrinology, 37, 491, 10.1016/j.psyneuen.2011.07.017 Zalla, 2011, Moral judgment in adults with autism spectrum disorders, Cognition, 121, 115, 10.1016/j.cognition.2011.06.004 Zheng, 2011, Developmental basis of sexually dimorphic digit ratios, Proc. Natl. Acad. Sci. U.S.A., 108, 16289, 10.1073/pnas.1108312108