Terminal Differentiation of Dendritic Cells

Advances in Immunology - Tập 120 - Trang 185-210 - 2013
Cyril Seillet1,2, Gabrielle T. Belz1,2
1Division of Molecular Immunology, Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia
2Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia

Tài liệu tham khảo

Aliberti, 2003, Essential role for ICSBP in the in vivo development of murine CD8alpha+ dendritic cells, Blood, 101, 305, 10.1182/blood-2002-04-1088 Allman, 2006, Ikaros is required for plasmacytoid dendritic cell differentiation, Blood, 108, 4025, 10.1182/blood-2006-03-007757 Allman, 2002, An invitation to T and more: Notch signaling in lymphopoiesis, Cell, 109, S1, 10.1016/S0092-8674(02)00689-X Anderson, 2000, Transcription factor PU.1 is necessary for development of thymic and myeloid progenitor-derived dendritic cells, Journal of Immunology, 164, 1855, 10.4049/jimmunol.164.4.1855 Asselin-Paturel, 2003, Mouse strain differences in plasmacytoid dendritic cell frequency and function revealed by a novel monoclonal antibody, Journal of Immunology, 171, 6466, 10.4049/jimmunol.171.12.6466 Auffray, 2009, CX3CR1+ CD115+ CD135+ common macrophage/DC precursors and the role of CX3CR1 in their response to inflammation, The Journal of Experimental Medicine, 206, 595, 10.1084/jem.20081385 Back, 2005, Visualizing PU.1 activity during hematopoiesis, Experimental Hematology, 33, 395, 10.1016/j.exphem.2004.12.010 Bajana, 2012, IRF4 promotes cutaneous dendritic cell migration to lymph nodes during homeostasis and inflammation, Journal of Immunology, 189, 3368, 10.4049/jimmunol.1102613 Bakri, 2005, Balance of MafB and PU.1 specifies alternative macrophage or dendritic cell fate, Blood, 105, 2707, 10.1182/blood-2004-04-1448 Bar-On, 2010, CX3CR1+ CD8alpha+ dendritic cells are a steady-state population related to plasmacytoid dendritic cells, Proceedings of the National Academy of Sciences of the United States of America, 107, 14745, 10.1073/pnas.1001562107 Becker, 2012, IRF-8 extinguishes neutrophil production and promotes dendritic cell lineage commitment in both myeloid and lymphoid mouse progenitors, Blood, 119, 2003, 10.1182/blood-2011-06-364976 Bedoui, 2009, Cross-presentation of viral and self antigens by skin-derived CD103+ dendritic cells, Nature Immunology, 10, 488, 10.1038/ni.1724 Belz, 2012, Transcriptional programming of the dendritic cell network, Nature Reviews Immunology, 12, 101, 10.1038/nri3149 Biswas, 2012, Dual regulation of IRF4 function in T and B cells is required for the coordination of T-B cell interactions and the prevention of autoimmunity, The Journal of Experimental Medicine, 209, 581, 10.1084/jem.20111195 Bogunovic, 2009, Origin of the lamina propria dendritic cell network, Immunity, 31, 513, 10.1016/j.immuni.2009.08.010 Burkly, 1995, Expression of relB is required for the development of thymic medulla and dendritic cells, Nature, 373, 531, 10.1038/373531a0 Carotta, 2010, The transcription factor PU.1 controls dendritic cell development and Flt3 cytokine receptor expression in a dose-dependent manner, Immunity, 32, 628, 10.1016/j.immuni.2010.05.005 Carreras, 2008, Estradiol acts directly on bone marrow myeloid progenitors to differentially regulate GM-CSF or Flt3 ligand-mediated dendritic cell differentiation, Journal of Immunology, 180, 727, 10.4049/jimmunol.180.2.727 Caton, 2007, Notch-RBP-J signaling controls the homeostasis of CD8− dendritic cells in the spleen, The Journal of Experimental Medicine, 204, 1653, 10.1084/jem.20062648 Chen, 1995, Neutrophils and monocytes express high levels of PU.1 (Spi-1) but not Spi-B, Blood, 85, 2918, 10.1182/blood.V85.10.2918.bloodjournal85102918 Cheng, 2003, Notch signaling is necessary but not sufficient for differentiation of dendritic cells, Blood, 102, 3980, 10.1182/blood-2003-04-1034 Cheong, 2010, Microbial stimulation fully differentiates monocytes to DC-SIGN/CD209(+) dendritic cells for immune T cell areas, Cell, 143, 416, 10.1016/j.cell.2010.09.039 Cisse, 2008, Transcription factor E2-2 is an essential and specific regulator of plasmacytoid dendritic cell development, Cell, 135, 37, 10.1016/j.cell.2008.09.016 Cowell, 1992, Transcriptional repression by a novel member of the bZIP family of transcription factors, Molecular and Cellular Biology, 12, 3070, 10.1128/MCB.12.7.3070 D’Amico, 2003, The early progenitors of mouse dendritic cells and plasmacytoid predendritic cells are within the bone marrow hemopoietic precursors expressing Flt3, The Journal of Experimental Medicine, 198, 293, 10.1084/jem.20030107 De Silva, 2012, The diverse roles of IRF4 in late germinal center B-cell differentiation, Immunological Reviews, 247, 73, 10.1111/j.1600-065X.2012.01113.x den Haan, 2000, CD8+ but not CD8− dendritic cells cross-prime cytotoxic T cells in vivo, The Journal of Experimental Medicine, 192, 1685, 10.1084/jem.192.12.1685 Dorsey, 1995, B-ATF: A novel human bZIP protein that associates with members of the AP-1 transcription factor family, Oncogene, 11, 2255 Douin-Echinard, 2008, Estrogen receptor alpha, but not beta, is required for optimal dendritic cell differentiation and CD40-induced cytokine production, Journal of Immunology, 180, 3661, 10.4049/jimmunol.180.6.3661 Dzionek, 2000, BDCA-2, BDCA-3, and BDCA-4: Three markers for distinct subsets of dendritic cells in human peripheral blood, Journal of Immunology, 165, 6037, 10.4049/jimmunol.165.11.6037 Echlin, 2000, B-ATF functions as a negative regulator of AP-1 mediated transcription and blocks cellular transformation by Ras and Fos, Oncogene, 19, 1752, 10.1038/sj.onc.1203491 Edelson, 2011, Batf3-dependent CD11b low/− peripheral dendritic cells are GM-CSF-independent and are not required for Th cell priming after subcutaneous immunization, PloS One, 6, e25660, 10.1371/journal.pone.0025660 Edelson, 2010, Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8alpha+ conventional dendritic cells, The Journal of Experimental Medicine, 207, 823, 10.1084/jem.20091627 Eguchi, 2011, Transcriptional control of adipose lipid handling by IRF4, Cell Metabolism, 13, 249, 10.1016/j.cmet.2011.02.005 Esashi, 2008, The signal transducer STAT5 inhibits plasmacytoid dendritic cell development by suppressing transcription factor IRF8, Immunity, 28, 509, 10.1016/j.immuni.2008.02.013 Feyerabend, 2009, Deletion of Notch1 converts pro-T cells to dendritic cells and promotes thymic B cells by cell-extrinsic and cell-intrinsic mechanisms, Immunity, 30, 67, 10.1016/j.immuni.2008.10.016 Fogg, 2006, A clonogenic bone marrow progenitor specific for macrophages and dendritic cells, Science, 311, 83, 10.1126/science.1117729 Gascoyne, 2009, The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development, Nature Immunology, 10, 1118, 10.1038/ni.1787 Geissmann, 2010, Development of monocytes, macrophages, and dendritic cells, Science, 327, 656, 10.1126/science.1178331 Georgopoulos, 1994, The Ikaros gene is required for the development of all lymphoid lineages, Cell, 79, 143, 10.1016/0092-8674(94)90407-3 Ghosh, 2010, Continuous expression of the transcription factor e2-2 maintains the cell fate of mature plasmacytoid dendritic cells, Immunity, 33, 905, 10.1016/j.immuni.2010.11.023 Ginhoux, 2009, The origin and development of nonlymphoid tissue CD103+ DCs, The Journal of Experimental Medicine, 206, 3115, 10.1084/jem.20091756 Ginhoux, 2006, Langerhans cells arise from monocytes in vivo, Nature Immunology, 7, 265, 10.1038/ni1307 Glasmacher, 2012, A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes, Science, 338, 975, 10.1126/science.1228309 Grouard, 1997, The enigmatic plasmacytoid T cells develop into dendritic cells with interleukin (IL)-3 and CD40-ligand, The Journal of Experimental Medicine, 185, 1101, 10.1084/jem.185.6.1101 Guerriero, 2000, PU.1 is required for myeloid-derived but not lymphoid-derived dendritic cells, Blood, 95, 879, 10.1182/blood.V95.3.879.003k13_879_885 Hacker, 2003, Transcriptional profiling identifies Id2 function in dendritic cell development, Nature Immunology, 4, 380, 10.1038/ni903 Hambleton, 2011, IRF8 mutations and human dendritic-cell immunodeficiency, The New England Journal of Medicine, 365, 127, 10.1056/NEJMoa1100066 Hayden, 2008, Shared principles in NF-kappaB signaling, Cell, 132, 344, 10.1016/j.cell.2008.01.020 Henri, 2001, The dendritic cell populations of mouse lymph nodes, Journal of Immunology, 167, 741, 10.4049/jimmunol.167.2.741 Hildner, 2008, Batf3 deficiency reveals a critical role for CD8alpha+ dendritic cells in cytotoxic T cell immunity, Science, 322, 1097, 10.1126/science.1164206 Hohaus, 1995, PU.1 (Spi-1) and C/EBP alpha regulate expression of the granulocyte-macrophage colony-stimulating factor receptor alpha gene, Molecular and Cellular Biology, 15, 5830, 10.1128/MCB.15.10.5830 Holtschke, 1996, Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene, Cell, 87, 307, 10.1016/S0092-8674(00)81348-3 Hume, 2011, Applications of myeloid-specific promoters in transgenic mice support in vivo imaging and functional genomics but do not support the concept of distinct macrophage and dendritic cell lineages or roles in immunity, Journal of Leukocyte Biology, 89, 525, 10.1189/jlb.0810472 Jackson, 2011, Id2 expression delineates differential checkpoints in the genetic program of CD8alpha(+) and CD103(+) dendritic cell lineages, EMBO Journal, 30, 2690, 10.1038/emboj.2011.163 Kamizono, 2009, Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo, The Journal of Experimental Medicine, 206, 2977, 10.1084/jem.20092176 Kashiwada, 2011, NFIL3/E4BP4 is a key transcription factor for CD8{alpha}+ dendritic cell development, Blood, 117, 6193, 10.1182/blood-2010-07-295873 Kingston, 2009, The concerted action of GM-CSF and Flt3-ligand on in vivo dendritic cell homeostasis, Blood, 114, 835, 10.1182/blood-2009-02-206318 Kusunoki, 2003, TH2 dominance and defective development of a CD8+ dendritic cell subset in Id2-deficient mice, The Journal of Allergy and Clinical Immunology, 111, 136, 10.1067/mai.2003.29 Laouar, 2003, STAT3 is required for Flt3L-dependent dendritic cell differentiation, Immunity, 19, 903, 10.1016/S1074-7613(03)00332-7 Leon, 2007, Monocyte-derived dendritic cells formed at the infection site control the induction of protective T helper 1 responses against Leishmania, Immunity, 26, 519, 10.1016/j.immuni.2007.01.017 Lewis, 2011, Notch2 receptor signaling controls functional differentiation of dendritic cells in the spleen and intestine, Immunity, 35, 780, 10.1016/j.immuni.2011.08.013 Li, 2012, BATF-JUN is critical for IRF4-mediated transcription in T cells, Nature, 490, 543, 10.1038/nature11530 Li, 2012, The signal transducers STAT5 and STAT3 control expression of Id2 and E2-2 during dendritic cell development, Blood, 120, 4363, 10.1182/blood-2012-07-441311 Meredith, 2012, Expression of the zinc finger transcription factor zDC (Zbtb46, Btbd4) defines the classical dendritic cell lineage, The Journal of Experimental Medicine, 209, 1153, 10.1084/jem.20112675 Miller, 2012, Deciphering the transcriptional network of the dendritic cell lineage, Nature Immunology, 13, 888, 10.1038/ni.2370 Murre, 1989, A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD and Myc proteins, Cell, 56, 777, 10.1016/0092-8674(89)90682-X Murre, 1989, Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence, Cell, 58, 537, 10.1016/0092-8674(89)90434-0 Nagasawa, 2008, Development of human plasmacytoid dendritic cells depends on the combined action of the basic helix-loop-helix factor E2-2 and the Ets factor Spi-B, European Journal of Immunology, 38, 2389, 10.1002/eji.200838470 Naik, 2006, Intrasplenic steady-state dendritic cell precursors that are distinct from monocytes, Nature Immunology, 7, 663, 10.1038/ni1340 Naik, 2007, Development of plasmacytoid and conventional dendritic cell subtypes from single precursor cells derived in vitro and in vivo, Nature Immunology, 8, 1217, 10.1038/ni1522 Nichogiannopoulou, 1999, Defects in hemopoietic stem cell activity in Ikaros mutant mice, The Journal of Experimental Medicine, 190, 1201, 10.1084/jem.190.9.1201 Nutt, 2005, Dynamic regulation of PU.1 expression in multipotent hematopoietic progenitors, The Journal of Experimental Medicine, 201, 221, 10.1084/jem.20041535 Omatsu, 2005, Development of murine plasmacytoid dendritic cells defined by increased expression of an inhibitory NK receptor, Ly49Q, Journal of Immunology, 174, 6657, 10.4049/jimmunol.174.11.6657 Onai, 2007, Identification of clonogenic common Flt3+M-CSFR+ plasmacytoid and conventional dendritic cell progenitors in mouse bone marrow, Nature Immunology, 8, 1207, 10.1038/ni1518 Onai, 2006, Activation of the Flt3 signal transduction cascade rescues and enhances type I interferon-producing and dendritic cell development, The Journal of Experimental Medicine, 203, 227, 10.1084/jem.20051645 Osborne, 2007, Notch signalling during peripheral T-cell activation and differentiation, Nature Reviews Immunology, 7, 64, 10.1038/nri1998 Radtke, 2000, Notch1 deficiency dissociates the intrathymic development of dendritic cells and T cells, The Journal of Experimental Medicine, 191, 1085, 10.1084/jem.191.7.1085 Rankin, 2013, Diversity, function and transcriptional regulation of gut innate lymphocytes, Frontiers in Immunology, 4, 22, 10.3389/fimmu.2013.00022 Rathinam, 2005, The transcriptional repressor Gfi1 controls STAT3-dependent dendritic cell development and function, Immunity, 22, 717, 10.1016/j.immuni.2005.04.007 Ray-Gallet, 1995, DNA binding specificities of Spi-1/PU.1 and Spi-B transcription factors and identification of a Spi-1/Spi-B binding site in the c-fes/c-fps promoter, Oncogene, 11, 303 Sasaki, 2012, Spi-B is critical for plasmacytoid dendritic cell function and development, Blood, 120, 4733, 10.1182/blood-2012-06-436527 Satpathy, 2012, Zbtb46 expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages, The Journal of Experimental Medicine, 209, 1135, 10.1084/jem.20120030 Schiavoni, 2004, ICSBP is critically involved in the normal development and trafficking of Langerhans cells and dermal dendritic cells, Blood, 103, 2221, 10.1182/blood-2003-09-3007 Schiavoni, 2002, ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells, The Journal of Experimental Medicine, 196, 1415, 10.1084/jem.20021263 Schotte, 2004, The ETS transcription factor Spi-B is required for human plasmacytoid dendritic cell development, The Journal of Experimental Medicine, 200, 1503, 10.1084/jem.20041231 Schotte, 2003, The transcription factor Spi-B is expressed in plasmacytoid DC precursors and inhibits T-, B-, and NK-cell development, Blood, 101, 1015, 10.1182/blood-2002-02-0438 Segura, 2013, Human inflammatory dendritic cells induce Th17 cell differentiation, Immunity, 38, 336, 10.1016/j.immuni.2012.10.018 Seillet, 2013, CD8alpha+ DCs can be induced in the absence of transcription factors Id2, Nfil3 and Batf3, Blood, 121, 1574, 10.1182/blood-2012-07-445650 Seillet, 2012, The TLR-mediated response of plasmacytoid dendritic cells is positively regulated by estradiol in vivo through cell-intrinsic estrogen receptor alpha signaling, Blood, 119, 454, 10.1182/blood-2011-08-371831 Sere, 2012, Two distinct types of Langerhans cells populate the skin during steady state and inflammation, Immunity, 37, 905, 10.1016/j.immuni.2012.07.019 Siegal, 1999, The nature of the principal type 1 interferon-producing cells in human blood, Science, 284, 1835, 10.1126/science.284.5421.1835 Spits, 2000, Id2 and Id3 inhibit development of CD34(+) stem cells into predendritic cell (pre-DC)2 but not into pre-DC1. Evidence for a lymphoid origin of pre-DC2, The Journal of Experimental Medicine, 192, 1775, 10.1084/jem.192.12.1775 Spooner, 2009, A recurrent network involving the transcription factors PU.1 and Gfi1 orchestrates innate and adaptive immune cell fates, Immunity, 31, 576, 10.1016/j.immuni.2009.07.011 Su, 1997, Defective B cell receptor-mediated responses in mice lacking the Ets protein, Spi-B, EMBO Journal, 16, 7118, 10.1093/emboj/16.23.7118 Sung, 2006, A major lung CD103 ({alpha}E)-beta7 integrin-positive epithelial dendritic cell population expressing langerin and tight junction proteins, Journal of Immunology, 176, 2161, 10.4049/jimmunol.176.4.2161 Suzuki, 2004, Critical roles of interferon regulatory factor 4 in CD11bhighCD8alpha− dendritic cell development, Proceedings of the National Academy of Sciences of the United States of America, 101, 8981, 10.1073/pnas.0402139101 Tailor, 2008, The BXH2 mutation in IRF8 differentially impairs dendritic cell subset development in the mouse, Blood, 111, 1942, 10.1182/blood-2007-07-100750 Tamura, 2005, IFN regulatory factor-4 and -8 govern dendritic cell subset development and their functional diversity, Journal of Immunology, 174, 2573, 10.4049/jimmunol.174.5.2573 Tsujimura, 2003, ICSBP/IRF-8 retrovirus transduction rescues dendritic cell development in vitro, Blood, 101, 961, 10.1182/blood-2002-05-1327 Tsujimura, 2003, Cutting edge: IFN consensus sequence binding protein/IFN regulatory factor 8 drives the development of type I IFN-producing plasmacytoid dendritic cells, Journal of Immunology, 170, 1131, 10.4049/jimmunol.170.3.1131 Turcotte, 2004, Genetic control of myeloproliferation in BXH-2 mice, Blood, 103, 2343, 10.1182/blood-2003-06-1852 Tussiwand, 2012, Compensatory dendritic cell development mediated by BATF-IRF interactions, Nature, 490, 502, 10.1038/nature11531 Vallabhapurapu, 2009, Regulation and function of NF-kappaB transcription factors in the immune system, Annual Reviews in Immunology, 27, 693, 10.1146/annurev.immunol.021908.132641 Vremec, 2000, CD4 and CD8 expression by dendritic cell subtypes in mouse thymus and spleen, Journal of Immunology, 164, 2978, 10.4049/jimmunol.164.6.2978 Wang, 1996, Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation, Immunity, 5, 537, 10.1016/S1074-7613(00)80269-1 Wu, 1998, RelB is essential for the development of myeloid-related CD8alpha− dendritic cells but not of lymphoid-related CD8alpha+ dendritic cells, Immunity, 9, 839, 10.1016/S1074-7613(00)80649-4 Wu, 1997, Cell-autonomous defects in dendritic cell populations of Ikaros mutant mice point to a developmental relationship with the lymphoid lineage, Immunity, 7, 483, 10.1016/S1074-7613(00)80370-2 Zhang, 1994, The macrophage transcription factor PU.1 directs tissue-specific expression of the macrophage colony-stimulating factor receptor, Molecular and Cellular Biology, 14, 373, 10.1128/MCB.14.1.373 Zhang, 2006, Characterization of Siglec-H as a novel endocytic receptor expressed on murine plasmacytoid dendritic cell precursors, Blood, 107, 3600, 10.1182/blood-2005-09-3842 Zhang, 1995, Molecular cloning and characterization of NF-IL3A, a transcriptional activator of the human interleukin-3 promoter, Molecular and Cellular Biology, 15, 6055, 10.1128/MCB.15.11.6055 Zhou, 2009, Notch and wingless signaling cooperate in regulation of dendritic cell differentiation, Immunity, 30, 845, 10.1016/j.immuni.2009.03.021