Tensegrity architecture explains linear stiffening and predicts softening of living cells

Amos, 1991 Coughlin, 1997, A tensegrity structure with buckling compression elements, ASME Journal of Applied Mechanics, 64, 480, 10.1115/1.2788918 Felgner, 1996, Flexural rigidity of microtubules measured with the use of optical tweezers, Journal of Cell Science, 109, 509, 10.1242/jcs.109.2.509 Gittes, 1993, Flexural rigidity of microtubules and actin filaments measured from thermal fluctuations in shape, Journal of Cell Biology, 120, 923, 10.1083/jcb.120.4.923 Harris, 1980, Silcone rubber substrata, Science, 208, 177, 10.1126/science.6987736 Heidemann, 1999, Direct observations of the mechanical behavior of the cytoskeleton in living fibroblasts, Journal of Cell Biology, 145, 109, 10.1083/jcb.145.1.109 Ingber, 1993, Cellular tensegrity, Journal of Cell Science, 104, 613, 10.1242/jcs.104.3.613 Ingber, D.E., 1998. The architecture of life. Scientific American, January. Maniotis, 1997, Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure, Proceedings of the National Academy of Sciences USA, 94, 849, 10.1073/pnas.94.3.849 Thoumine, 1995, Elongation of confluent endothelial cells in culture, Experimental Cell Research, 219, 427, 10.1006/excr.1995.1249 Timoshenko, 1961 Volokh, 1999, Non-linear analysis of underconstrained structures, International Journal of Solids & Structures, 36, 2175, 10.1016/S0020-7683(98)00112-7 Volokh, K., Yu., Vilnay, O., 1997a. New classes of reticulated underconstrained structures. International Journal of Solids & Structures 34, 1093–1104. Volokh, K., Yu., Vilnay, O., 1997b. “Natural”, “kinematic” and “elastic” displacements of underconstrained structures. International Journal of Solids & Structures 34, 911–930. Wang, 1993, Mechanotransduction across the cell surface and through the cytosceleton, Science, 260, 1124, 10.1126/science.7684161 Wang, 1994, Control of cytosceletal mechanics by extracellular matrix, cell shape, and mechanical tension, Biophysical Journal, 66, 2181, 10.1016/S0006-3495(94)81014-8 Wolfram, 1991