Ten inherited disorders in purebred dogs by functional breed groupings

Anita M. Oberbauer1, Janelle M. Belanger1, Thomas P. Bellumori1, Danika L. Bannasch2, Famula Tr1
1Department of Animal Science, College of Agricultural and Environmental Sciences, University of California, Davis, Davis, USA
2Department of Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, Davis, USA

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Shearin AL, Ostrander EA. Leading the way: canine models of genomics and disease. Dis Model Mech. 2010;3:27–34.

Karlsson EK, Lindblad-Toh K. Leader of the pack: gene mapping in dogs and other model organisms. Nat Rev Genet. 2008;9:713–25.

Leroy G. Genetic diversity, inbreeding and breeding practices in dogs: results from pedigree analyses. Vet J. 2011;189(2):177–82.

O'Neill DG, Church DB, McGreevy PD, Thomson PC, Brodbelt DC. Prevalence of disorders recorded in dogs attending primary-care veterinary practices in England. PLoS ONE. 2014;9:90501.

Farrow T, Keown A, Farnworth M. An exploration of attitudes towards pedigree dogs and their disorders as expressed by a sample of companion animal veterinarians in New Zealand. N Z Vet J. 2014;1–21.

Bellumori TP, Famula TR, Bannasch DL, Belanger JM, Oberbauer AM. Prevalence of inherited disorders among mixed-breed and purebred dogs: 27,254 cases (1995–2010). J Am Vet Med Assoc. 2013;242:1549–55.

Ubbink G, Van de Broek J, Hazewinkel H, Rothuizen J. Cluster analysis of the genetic heterogeneity and disease distributions in purebred dog populations. Vet Record. 1998;142:209–13.

Parker HG, Meurs KM, Ostrander EA. Finding cardiovascular disease genes in the dog. J Vet Cardiol. 2006;8:115–27.

Bonnett B, Egenvall A, Olson P, Hedhammer Å. Mortality in over 350,000 insured Swedish dogs from 1995–2000: I. Breed-, gender-, age- and cause-specific rates. Acta Vet Scand. 2005;46:105–20.

Oberbauer AM, Benemann K, Belanger JM, Wagner D, Ward J, Famula TR. Inheritance of hypoadrenocorticism in bearded collies. Am J Vet Res. 2002;63:643–7.

Lund E. Epidemiology of canine atopic dermatitis. Vet Focus. 2001;21:32–3.

Nødtvedt A, Egenvall A, Bergval K, Hedhammar Å. Incidence of and risk factors for atopic dermatitis in a Swedish population of insured dogs. Vet Record. 2006;159:241–6.

Schick R, Fadok V. Responses of atopic dogs to regional allergens: 268 cases (1981–1984). J Am Vet Med Assoc. 1986;189:1493.

Wayne RK, VonHoldt BM. Evolutionary genomics of dog domestication. Mamm Genome. 2012;23:3–18.

Collins L, Asher L, Summers J, Diesel G, McGreevy P. Welfare epidemiology as a tool to assess the welfare impact of inherited defects on the pedigree dog population. Anim Welf. 2010;19:67–75.

O'Grady MR, Holmberg DL, Miller CW, Cockshutt JR. Canine congenital aortic stenosis: a review of the literature and commentary. Can Vet J. 1989;30:811.

Patterson D, Detweiler D. Predominance of German shepherd and Boxer breeds among dogs with congenital subaortic stenosis. Am Heart J. 1963;65:429–30.

Tidholm A. Retrospective study of congenital heart defects in 151 dogs. J Small Animal Practice. 1997;38:94–8.

Ohad D, Avrahami A, Waner T, David L. The occurrence and suspected mode of inheritance of congenital subaortic stenosis and tricuspid valve dysplasia in Dogue de Bordeaux dogs. Vet J. 2013;197:351–7.

Menegazzo L, Bussadori C, Chiavegato D, Quintavalla C, Bonfatti V, Guglielmini C, et al. The relevance of echocardiography heart measures for breeding against the risk of subaortic and pulmonic stenosis in Boxer dogs. J Anim Sci. 2012;90:419–28.

Reist-Marti S, Dolf G, Leeb T, Kottmann S, Kietzmann S, Butenhoff K, et al. Genetic evidence of subaortic stenosis in the Newfoundland dog. Vet Record. 2012;170:597–7.

Coopman F, Verhoeven G, Saunders J, Duchateau L, Van Bree H. Prevalence of hip dysplasia, elbow dysplasia and humeral head osteochondrosis in dog breeds in Belgium. Vet Record. 2008;163:654–8.

LaFond E, Breur GJ, Austin CC. Breed susceptibility for developmental orthopedic diseases in dogs. J Am Anim Hosp Assoc. 2002;38:467.

Brockman D, Washabau R, Drobatz K. Canine gastric dilatation/volvulus syndrome in a veterinary critical care unit: 295 cases (1986–1992). J Am Vet Med Assoc. 1995;207:460–4.

Glickman LT, Glickman NW, Schellenberg DB, Raghavan M, Lee TL. Incidence of and breed-related risk factors for gastric dilatation-volvulus in dogs. J Am Vet Med Assoc. 2000;216:40–5.

Packer RM, Hendricks A, Volk HA, Shihab NK, Burn CC. How long and low can you go? Effect of conformation on the risk of thoracolumbar intervertebral disc extrusion in domestic dogs. PLoS ONE. 2013;8:e69650.

Trevejo R, Yang M, Lund EM. Epidemiology of surgical castration of dogs and cats in the United States. J Am Vet Med Assoc. 2011;238:898–904.

Leroy G. Inbreeding depression in livestock species: review and meta‐analysis. Animal Genet. 2014;45(5):618–28.

Meyers‐Wallen V. Ethics and genetic selection in purebred dogs. Reproduc Domestic Animals. 2003;38:73–6.

Jansson M, Laikre L. Recent breeding history of dog breeds in Sweden: modest rates of inbreeding, extensive loss of genetic diversity and lack of correlation between inbreeding and health. Genetics: J Animal Breeding and; 2013.

Calboli FC, Sampson J, Fretwell N, Balding DJ. Population structure and inbreeding from pedigree analysis of purebred dogs. Genetics. 2008;179:593–601.

Comhaire FH. The relation between canine hip pysplasia, genetic diversity and inbreeding by breed. Open J Veterinary Med. 2014;2014.

Mellanby RJ, Ogden R, Clements DN, French AT, Gow AG, Powell R, et al. Population structure and genetic heterogeneity in popular dog breeds in the UK. Veterinary J. 2013;196:92–7.

Angles J, Kennedy L, Pedersen N. Frequency and distribution of alleles of canine MHC‐II DLA‐DQB1, DLA‐DQA1 and DLA‐DRB1 in 25 representative American Kennel Club breeds. Tissue Antigens. 2005;66:173–84.

Castro-Prieto A, Wachter B, Sommer S. Cheetah paradigm revisited: MHC diversity in the world’s largest free-ranging population. Mol Biol Evol. 2011;28:1455–68.

Wade CM. Inbreeding and genetic diversity in dogs: results from DNA analysis. Veterinary J. 2011;189:183–8.

Collins LM, Asher L, Summers J, McGreevy P. Getting priorities straight: risk assessment and decision-making in the improvement of inherited disorders in pedigree dogs. Veterinary J. 2011;189:147–54.

Lawler DF, Evans RH, Reetz JA, Sackman JE, Smith GK. Suspected hip dysplasia in a red fox. Illinois State Museum Landscape History Program 2014. Technical Report No. 2014-0000-02.

Voith VL, Ingram E, Mitsouras K, Irizarry K. Comparison of adoption agency breed identification and DNA breed identification of dogs. J Appl Anim Welf Sci. 2009;12:253–62.

Hulley SB, Cummings SR, Browner WS, Grady DG, Newman TB. Designing Clinical Research. Philadelphia PA: Lippincott Williams & Wilkins; 2007.