Temporal Control of Cell-Specific Transgene Expression in <i>Caenorhabditis elegans</i>

Genetics - Tập 176 Số 4 - Trang 2651-2655 - 2007
Taulant Bacaj1, Shai Shaham1
1Laboratory of Developmental Genetics, The Rockefeller University, New York, New York 10021

Tóm tắt

Abstract Cell-specific promoters allow only spatial control of transgene expression in Caenorhabditis elegans. We describe a method, using cell-specific rescue of heat-shock factor-1 (hsf-1) mutants, that allows spatial and temporal regulation of transgene expression. We demonstrate the utility of this method for timed reporter gene expression and for temporal studies of gene function.

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