Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA
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Allsopp, 1992, Telomere length predicts the replicative capacity of human fibroblasts, Proc. Natl. Acad. Sci. USA, 89, 10114, 10.1073/pnas.89.21.10114
Ausubel, R.M., Brent, R., Kingston, R., Moore, D., Seidman, J.G., Smith, J.A., and Struhl, K., eds. (1993). Introduction of DNA into mammalian cells. In Current Protocols in Molecular Biology. (New York: Wiley and Sons, Inc.), pp. 9.1.1.
Bednarek, 1995, Increased telomerase activity in mouse skin pre-malignant progression, Cancer Res., 55, 4566
Blasco, 1995, Functional characterization and developmental regulation of mouse telomerase RNA, Science, 269, 1267, 10.1126/science.7544492
Blasco, 1996, Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis, Nat. Genet., 12, 200, 10.1038/ng0296-200
Broccoli, 1996, Telomerase activation in mouse mammary tumors, Mol. Cell. Biol., 16, 3765, 10.1128/MCB.16.7.3765
Bryan, 1995, Telomere elongation in immortal human cells without detectable telomerase activity, EMBO J., 14, 4240, 10.1002/j.1460-2075.1995.tb00098.x
Chadeneau, 1995, Telomerase activity in normal and malignant murine tissues, Oncogene, 11, 893
Conzen, 1995, The three transforming regions of SV40 T antigen are required for immortalization of primary mouse embryo fibroblasts, Oncogene, 11, 2295
Cooke, H.J., and Smith, B.A. (1986). Variability at the telomeres of human X/Y pseudoautosomal region. Cold Spring Harbor Symp. Quant. Biol. LI, 213–219.
Counter, 1992, Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity, EMBO J., 11, 1921, 10.1002/j.1460-2075.1992.tb05245.x
Drost, 1995, Biological basis of germline mutation, Environ. Mol. Mutagen., 25, 48, 10.1002/em.2850250609
Garagna, 1995, Robertsonian metacentrics of the house mouse lose telomeric sequences but retain some minor satellite DNA in the pericentromeric area, Chromosoma, 103, 685, 10.1007/BF00344229
Greider, 1996, Telomere length regulation, Annu. Rev. Biochemistry, 65, 337, 10.1146/annurev.bi.65.070196.002005
Greider, 1985, Identification of a specific telomere terminal transferase activity in Tetrahymena extracts, Cell, 43, 405, 10.1016/0092-8674(85)90170-9
Greider, 1989, A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis, Nature, 337, 331, 10.1038/337331a0
Hanish, 1995, Stringent sequence requirements for the formation of human telomeres, Proc. Natl. Acad. Sci. USA, 91, 8861, 10.1073/pnas.91.19.8861
Harley, C.B. (1990). Aging in cultured human fibroblasts. In Methods in Molecular Biology, J.W. Pollard and J.M. Walker, eds. (Clifton, NJ: The Humana Press, Inc.), pp. 25–32.
Harley, 1990, Telomeres shorten during aging of human fibroblasts, Nature, 345, 458, 10.1038/345458a0
Harley, 1994, Telomerase, cell immortality and cancer, Cold Spring Harbor. Symp. Quant. Biol., 59, 307, 10.1101/SQB.1994.059.01.035
Harrington, 1997, A mammalian telomerase-associated protein, Science, 275, 973, 10.1126/science.275.5302.973
Harvey, 1991, p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts, Genes Dev., 5, 2375, 10.1101/gad.5.12b.2375
Hastie, 1990, Telomere reduction in human colorectal carcinoma and with aging, Nature, 346, 866, 10.1038/346866a0
Ikram, 1994, The biological clock that measures the mitotic life-span of mouse embryo fibroblasts continues to function in the presence of simian virus 40 large tumor antigen, Proc. Natl. Acad. Sci. USA, 91, 6448, 10.1073/pnas.91.14.6448
Kim, 1994, Specific association of human telomerase activity with immortal cells and cancer, Science, 266, 2011, 10.1126/science.7605428
Kipling, 1991, Mouse minor satellite genetically maps to the centromere and is physically linked to the proximal telomere, Genomics, 11, 235, 10.1016/0888-7543(91)90128-2
Kraemer, 1986, Spontaneous immortalization rate of cultured Chinese hamster cells, J. Natl. Cancer Inst., 76, 703, 10.1093/jnci/76.4.703
Kyo, 1997, Telomerase activity in human endometrium, Cancer Res., 57, 610
Lansdorp, 1996, Heterogeneity in telomere length of human chromosomes, Hum. Mol. Genet., 5, 685, 10.1093/hmg/5.5.685
Lundblad, 1993, An alternative pathway for yeast telomere maintenance rescues est1- senescence, Cell, 73, 347, 10.1016/0092-8674(93)90234-H
McEachern, 1996, Cap-prevented recombination between terminal telomeric repeats arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase, Genes Dev., 10, 1822, 10.1101/gad.10.14.1822
Meek, 1977, Establishment of mouse embryonic cells in vitro. Relationship of DNA synthesis, senescence, and malignant transformation, Exp. Cell Res., 107, 277, 10.1016/0014-4827(77)90350-0
Nanda, 1995, Loss of telomeric sites in the chromosomes of Mus musculus domesticus (Rodentia: Muridae) during Robertsonian rearrangement, Chrom. Res., 3, 399, 10.1007/BF00713889
Prowse, 1995, Developmental and tissue specific regulation of mouse telomerase and telomere length, Proc. Natl. Acad. Sci. USA, 92, 4818, 10.1073/pnas.92.11.4818
Prowse, 1993, Identification of a nonprocessive telomerase activity from mouse cells, Proc. Natl. Acad. Sci. USA, 90, 1493, 10.1073/pnas.90.4.1493
Ramirez-Solis, 1993, Gene targeting in embryonic stem cells, Meth. Enzymol., 225, 855, 10.1016/0076-6879(93)25054-6
Rittling, 1996, Clonal nature of spontaneously immortalized 3T3 cells, Exp. Cell Res., 229, 7, 10.1006/excr.1996.0337
Serrano, 1996, Role of the INK4a locus in tumor suppression and cell mortality, Cell, 85, 27, 10.1016/S0092-8674(00)81079-X
Serrano, 1997, Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INC4a, Cell, 88, 593, 10.1016/S0092-8674(00)81902-9
Shay, 1997, A survey of telomerase activity in human cancer, Eur. J. Cancer, 33, 787, 10.1016/S0959-8049(97)00062-2
Starling, 1990, Extensive telomere repeat arrays in mouse are hypervarible, Nucl. Acids Res., 18, 6881, 10.1093/nar/18.23.6881
Thomas, 1987, Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells, Cell, 51, 503, 10.1016/0092-8674(87)90646-5
Todaro, 1963, Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines, J. Cell Biol., 17, 299, 10.1083/jcb.17.2.299
Tybulewicz, 1991, Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene, Cell, 65, 1153, 10.1016/0092-8674(91)90011-M
Yu, 1990, In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs, Nature, 344, 126, 10.1038/344126a0