Targeting the Microtubules in Breast Cancer Beyond Taxanes: The Epothilones

Oncologist - Tập 12 Số 3 - Trang 271-280 - 2007
Javier Cortés1, José Baselga1
1Department of Oncology, Vall d'Hebron University Hospital, Barcelona, Spain

Tóm tắt

Learning Objectives

After completing this course, the reader will be able to: Describe the mechanism of action of epothilones and the different epothilone analogs in clinical development.Discuss the current status and the results of phase II trials with epothilone analogs in metastatic breast cancer.Explain why epothilone may have utility in combination with other cytotoxic chemotherapeutic agents for treating metastatic breast cancer.

CME Access and take the CME test online and receive 1 AMA PRA Category 1 Credit™ at CME.TheOncologist.com

Từ khóa


Tài liệu tham khảo

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Trastuzumab, Ixabepilone, and Carboplatin in Treating Patients With HER-2 Positive Metastatic Breast Cancer

Trastuzumab and Ixabepilone in Treating Women With HER-2 Positive Metastatic Breast Cancer

Epothilone (Ixabepilone) Plus Capecitabine Versus Capecitabine Alone in Patients With Advanced Breast Cancer

Novel Epothilone Plus Capecitabine Versus Capecitabine Alone in Patients With Advanced Breast Cancer

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