Targeting p38α Increases DNA Damage, Chromosome Instability, and the Anti-tumoral Response to Taxanes in Breast Cancer Cells

Cancer Cell - Tập 33 Số 6 - Trang 1094-1110.e8 - 2018
Begoña Cánovas1, Ana Igea1, Alessandro A. Sartori2, Roger R. Gomis3,1,4, Tanya T. Paull5, Michitaka Isoda1, Héctor Pérez‐Montoyo6, Violeta Serra7, Eva González‐Suárez6, Travis H. Stracker1, Àngel R. Nebreda3,1
1Institute for Research in Biomedicine (IRB Barcelona), Barcelona Institute of Science and Technology, Barcelona 08028, Spain
2University of Zurich, Institute of Molecular Cancer Research, Zurich 8057, Switzerland
3ICREA, Pg. Lluís Companys, 23, Barcelona 08010, Spain
4Universitat de Barcelona and CIBERONC, Barcelona, Spain
5Howard Hughes Medical Institute, University of Texas at Austin, Austin, TX 78712, USA
6Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), Barcelona 08908, Spain
7Vall d'Hebron Institute of Oncology (VHIO), Barcelona 08035, Spain

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