1Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
2Women's Cancer Research Center, UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
3Department of Oncology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, P. R. China
4UPMC St. Margaret Hospital, Pittsburgh, PA 15215, USA