Targeting Ergosterol Biosynthesis in Leishmania donovani: Essentiality of Sterol 14alpha-demethylase

PLOS Neglected Tropical Diseases - Tập 9 Số 3 - Trang e0003588
Laura‐Isobel McCall1, Amale El Aroussi2, Jun Yong Choi3, Débora Vieira2, Géraldine De Muylder2, Jonathan B. Johnston4, Steven Chen5, Danielle Kellar2, Jair L. Siqueira-Neto1, William Roush3, Larissa M. Podust1, James H. McKerrow1
1Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California-San Diego, La Jolla, California, United States of America.
2Department of Pathology, University of California, San Francisco, San Francisco, California, United States of America.
3Department of Chemistry, Scripps Florida, Jupiter, Florida, United States of America
4Department of Pharmaceutical Chemistry, University of California-San Francisco, San Francisco, California, United States of America.
5Small Molecule Discovery Center, University of California, San Francisco, San Francisco, California, United States of America.

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