Targeting BTK with Ibrutinib in Relapsed or Refractory Mantle-Cell Lymphoma

New England Journal of Medicine - Tập 369 Số 6 - Trang 507-516 - 2013
Michael Wang1,2, Simon Rule3, Peter Martin4, André Goy5, Rebecca Auer6, Brad S. Kahl7, Wojciech Jurczak8, Ranjana H. Advani9, Jorge Romaguera1, Michael E. Williams10, Jacqueline C. Barrientos11, Ewa Chmielowska12, John Radford13, Stephan Stilgenbauer14, Martin Dreyling15, W Wiktor-Jędrzejczak16, Peter Johnson17, Stephen E. Spurgeon18, Lei Li19, Liang Zhang1, Kate J. Newberry1, Zhishuo Ou1, Nancy Cheng20, Bingliang Fang21, Jesse McGreivy22, Fong Clow22, Joseph J. Buggy22, Betty Chang22, Darrin M. Beaupre22, Lori Kunkel22, Kristie A. Blum23
1Departments of Lymphoma and Myeloma
2Stem Cell Transplantation and Cellular Therapy
3Department of Haematology, Derriford Hospital, Plymouth
4Division of Hematology/Oncology, Weill Cornell Medical College, New York
5John Theurer Cancer Center at Hackensack University Medical Center, Hackensack, NJ
6Trust, London
7Department of Medicine, Division of Hematology and Oncology, University of Wisconsin, Madison
8Department of Hematology, Jagiellonian University, Krakow
9Department of Medicine, Division of Oncology, Stanford University Medical Center, Stanford
10University of Virginia School of Medicine, Charlottesville
11Chronic Lymphocytic Leukemia Research and Treatment Program, Division of Hematology and Medical Oncology, Department of Medicine, Hofstra North Shore–Long Island Jewish Medical Center, New Hyde Park, NY
12Oddzial Kliniczny Onkologii Centrum Onkologii, Bydgoszcz
13Christie NHS Foundation Trust and the University of Manchester, Manchester
14Universitätsklinikum Ulm, Klinik für Innere Medizin II, Ulm
15Klinikum der Universität München–Campus Grosshadern, Munich
16Medical University of Warsaw, Warsaw
17Cancer Research UK Centre, University of Southampton, Southampton
18Oregon Health and Science University, Portland
19Experimental Radiation Oncology
20University of Texas M.D. Anderson Cancer Center, and Baylor College of Medicine
21Thoracic and Cardiovascular Surgery
22Pharmacyclics, Sunnyvale
23Division of Hematology, Ohio State University Comprehensive Cancer Center, Columbus

Tóm tắt

Từ khóa


Tài liệu tham khảo

1997, Blood, 89, 3909, 10.1182/blood.V89.11.3909

Romaguera JE, 2010, Br J Haematol, 150, 200, 10.1111/j.1365-2141.2010.08228.x

10.1200/JCO.2012.44.4281

10.1038/nature08638

10.1007/s11899-012-0127-0

10.3109/08830185.2012.664797

10.1016/j.cellsig.2012.09.008

10.1038/nrd3655

10.18632/oncotarget.426

10.1182/blood-2011-03-343434

10.1111/j.1365-2141.2005.05883.x

Chang BY, Francesco M, Steggerda S, et al. Ibrutinib inhibits malignant cell adhesion and migration and reduces tumor burden in lymph node and bone marrow in a murine model of mantle cell dissemination and progression. Presented at the American Association for Cancer Research Annual Meeting 2013, Washington, DC, April 6–10, 2013.

10.1182/blood-2011-01-328484

10.1200/JCO.2012.42.7906

10.1056/NEJMoa1215637

10.1200/JCO.2006.09.2403

10.1016/0197-2456(89)90015-9

10.2307/2281868

10.1182/blood-2011-11-390989

10.1182/blood-2011-02-336065

10.1158/1078-0432.CCR-07-4409

Velasquez WS, 1994, J Clin Oncol, 12, 1169, 10.1200/JCO.1994.12.6.1169

Rodriguez MA, 1995, J Clin Oncol, 13, 1734, 10.1200/JCO.1995.13.7.1734

10.1002/cncr.23880

10.1093/annonc/mdg704

10.1200/JCO.2008.20.7977

10.1200/JCO.2006.07.9665

Thông tin
Thông tin xuất bản

New England Journal of Medicine

Tập 369 Số 6

507-516

Thông tin tác giả