Targeted inhibition of ANKRD1 disrupts sarcomeric ERK-GATA4 signal transduction and abrogates phenylephrine-induced cardiomyocyte hypertrophy

Cardiovascular Research - Tập 106 Số 2 - Trang 261-271 - 2015
Lin Zhong1, Manuel Chiusa1, Adrian G. Cadar1,2, Angel Lin1, Susan Samaras3, Jeffrey M. Davidson3,4, Chee Chew Lim1,2
1Department of Medicine, Cardiovascular Division, Vanderbilt University School of Medicine, 2220 Pierce Ave, Preston Research Building, Rm 332, Nashville, TN 37232, USA
2Department of Molecular Physiology & Biophysics, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
3Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
4Research Service, Veterans Affairs Tennessee Valley Healthcare System, Nashville, TN 37232, USA

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