Targeted biallelic integration of an inducible Caspase 9 suicide gene in iPSCs for safer therapies

Molecular Therapy - Methods & Clinical Development - Tập 26 - Trang 84-94 - 2022
Stephanie Wunderlich1,2, Alexandra Haase1,2,3, Sylvia Merkert1,2,3, Kirsten Jahn4, Maximillian Deest4, Helge Frieling4, Silke Glage2,5, Wilhelm Korte1,2, Andreas Martens1,2, Andreas Kirschning2,6, Andre Zeug2,7, Evgeni Ponimaskin2,7, Gudrun Göhring2,8, Mania Ackermann9,10, Nico Lachmann2,3,9,10,11, Thomas Moritz2,12,10, Robert Zweigerdt1,2, Ulrich Martin1,2,3
1Leibniz Research Laboratories for Biotechnology and Artificial Organs (LEBAO), Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, 30625 Hannover, Germany
2REBIRTH - Research Center for Translational Regenerative Medicine, 30625 Hannover, Germany
3Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Germany
4Laboratory for Molecular Neuroscience, Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, 30625 Hannover, Germany
5Institute for Laboratory Animal Science, Hannover Medical School, 30625 Hannover, Germany
6Institute for Organic Chemistry, Leibniz University Hannover, 30167 Hannover, Germany
7Department of Cellular Neurophysiology; Hannover Medical School, 30625 Hannover, Germany
8Department of Human Genetics, Hannover Medical School, 30625 Hannover, Germany
9Department of Pediatric Pneumology, Allergology and Neonatology, Hannover Medical School, 30625 Hannover, Germany
10Institute of Experimental Hematology, Hannover Medical School, 30625 Hannover, Germany
11Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, 30625 Hannover, Germany
12RG Reprogramming and Gene Therapy, Hannover Medical School, 30625 Hannover, Germany

Tài liệu tham khảo

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Molecular Therapy - Methods & Clinical Development

Tập 26

84-94

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