TRIM48 Promotes ASK1 Activation and Cell Death through Ubiquitination-Dependent Degradation of the ASK1-Negative Regulator PRMT1

Cell Reports - Tập 21 - Trang 2447-2457 - 2017
Yusuke Hirata1, Kazumi Katagiri2, Keita Nagaoka1, Tohru Morishita1, Yuki Kudoh1, Tomohisa Hatta3, Isao Naguro2, Kuniyuki Kano4, Tsuyoshi Udagawa5, Tohru Natsume3, Junken Aoki4, Toshifumi Inada5, Takuya Noguchi1, Hidenori Ichijo2, Atsushi Matsuzawa1
1Laboratory of Health Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan
2Laboratory of Cell Signaling, Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan
3Molecular Profiling Research Center for Drug Discovery, National Institute of Advanced Industrial Science and Technology, Tokyo, Japan
4Laboratory of Molecular and Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan
5Laboratory of Gene Regulation, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan

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