TNF-α Protects Human Primary Articular Chondrocytes from Nitric Oxide-Induced Apoptosis Via Nuclear Factor-κB

Laboratory Investigation - Tập 82 - Trang 1661-1672 - 2002
Biserka Relić1, Mohamed Bentires-Alj1, Clio Ribbens1, Nathalie Franchimont1, Pierre-André Guerne2, Valerie Benoît1, Marie-Paule Merville1, Vincent Bours1, Michel G Malaise1
1Center for Cellular and Molecular Therapy, University of Liège, Liège, Belgium
2Division of Rheumatology, University Hospital, Geneva, Switzerland

Tài liệu tham khảo

Aizawa, 2001, Induction of apoptosis in chondrocytes by tumor necrosis factor-alpha, J Orthop Res, 19, 785, 10.1016/S0736-0266(00)00078-4 Amin, 1999, Nitric oxide synthase and cyclooxygenases: Distribution, regulation, and intervention in arthritis, Curr Opin Rheumatol, 11, 202, 10.1097/00002281-199905000-00009 Aupperle, 2001, NF-kappa B regulation by I kappa B kinase-2 in rheumatoid arthritis synoviocytes, J Immunol, 166, 2705, 10.4049/jimmunol.166.4.2705 Bargou, 1997, Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells, J Clin Invest, 100, 2961, 10.1172/JCI119849 Barkett, 1999, Control of apoptosis by Rel/NF-kappaB transcription factors, Oncogene, 18, 6910, 10.1038/sj.onc.1203238 Beg, 1995, Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice, Genes Dev, 9, 2736, 10.1101/gad.9.22.2736 Bertrand, 1998, A role for nuclear factor kappaB in the antiapoptotic function of insulin, J Biol Chem, 273, 2931, 10.1074/jbc.273.5.2931 Blanco, 1995, Chondrocyte apoptosis induced by nitric oxide, Am J Pathol, 146, 75 Blanco, 1998, Osteoarthritis chondrocytes die by apoptosis: A possible pathway for osteoarthritis pathology, Arthritis Rheum, 41, 284, 10.1002/1529-0131(199802)41:2<284::AID-ART12>3.0.CO;2-T Bondenson, 2000, Effective adenoviral transfer of IkBα into human fibroblasts and chondrosarcoma cells reveals that the induction of matrix metalloproteinases and proinflammatory cytokines is nuclear factor-κB dependent, J Rheumatol, 27, 2078 Bours, 2000, Nuclear factor-kappa B, cancer, and apoptosis, Biochem Pharmacol, 60, 1085, 10.1016/S0006-2952(00)00391-9 Bowie, 2000, Oxidative stress and nuclear factor-kappaB activation: A reassessment of the evidence in the light of recent discoveries, Biochem Pharmacol, 59, 13, 10.1016/S0006-2952(99)00296-8 Brown, 1993, Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha, Proc Natl Acad Sci USA, 90, 2532, 10.1073/pnas.90.6.2532 Bureau, 2000, Mechanisms of persistent NF-kappa B activity in the bronchi of an animal model of asthma, J Immunol, 165, 5822, 10.4049/jimmunol.165.10.5822 Bureau, 2002, Constitutive nuclear factor-κB activity preserves homeostasis of quiescent mature lymphocytes and granulocytes by controlling the expression of distinct Bcl-2 family proteins, Blood, 99, 3683, 10.1182/blood.V99.10.3683 Buttke, 1993, Use of an aqueous soluble tetrazolium/formazan assay to measure viability and proliferation of lymphokine-dependent cell lines, J Immunol Methods, 157, 233, 10.1016/0022-1759(93)90092-L Cao, 2002, Many actions of cyclooxygenase-2 in cellular dynamics and in cancer, J Cell Physiol, 190, 279, 10.1002/jcp.10068 Colnot, 2001, Uncoupling of chondrocyte death and vascular invasion in mouse galectin 3 null mutant bones, Dev Biol, 229, 203, 10.1006/dbio.2000.9933 Dejardin, 1995, Highly-expressed p100/p52 (NFKB2) sequesters other NF-kappa B-related proteins in the cytoplasm of human breast cancer cells, Oncogene, 11, 1835 DiDonato, 1996, Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation, Mol Cell Biol, 16, 1295, 10.1128/MCB.16.4.1295 Feinberg, 1984, “A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.” Addendum, Anal Biochem, 137, 266, 10.1016/0003-2697(84)90381-6 Feldmann, 2001, Anti-TNF alpha therapy of rheumatoid arthritis: What have we learned, Annu Rev Immunol, 19, 163, 10.1146/annurev.immunol.19.1.163 Fischer, 2000, Tumor necrosis factor-alpha induced DNA cleavage in human articular chondrocytes may involve multiple endonucleolytic activities during apoptosis, Microsc Res Tech, 50, 236, 10.1002/1097-0029(20000801)50:3<236::AID-JEMT7>3.0.CO;2-E Foglieni, 2001, Fluorescent dyes for cell viability: An application on prefixed conditions, Histochem Cell Biol, 115, 223, 10.1007/s004180100249 Grell, 1994, TNF receptors TR60 and TR80 can mediate apoptosis via induction of distinct signal pathways, J Immunol, 153, 1963, 10.4049/jimmunol.153.5.1963 Habib, 1993, Demonstration of an inducible cyclooxygenase in human endothelial cells using antibodies raised against the carboxyl-terminal region of the cyclooxygenase-2, J Biol Chem, 268, 23448, 10.1016/S0021-9258(19)49483-0 Han, 1998, AP-1 and NF-kappaB regulation in rheumatoid arthritis and murine collagen-induced arthritis, Autoimmunity, 28, 197, 10.3109/08916939808995367 Handel, 1995, Nuclear factor-kappa B in rheumatoid synovium: Localization of p50 and p65, Arthritis Rheum, 38, 1762, 10.1002/art.1780381209 Hashimoto, 1998, Linkage of chondrocyte apoptosis and cartilage degradation in human osteoarthritis, Arthritis Rheum, 41, 1632, 10.1002/1529-0131(199809)41:9<1632::AID-ART14>3.0.CO;2-A Honda, 2000, Assessment of secondary necrosis of Jurkat cells using a new microscopic system and double staining method with annexin V and propidium iodide, Int J Oncol, 16, 283 Hu, 2001, An IkappaBalpha inhibitor causes leukemia cell death through a p38 MAP kinase-dependent, NF-kappaB-independent mechanism, Cancer Res, 61, 6290 Jobin, 1998, Inhibition of proinflammatory molecule production by adenovirus-mediated expression of a nuclear factor kappaB super-repressor in human intestinal epithelial cells, J Immunol, 160, 410, 10.4049/jimmunol.160.1.410 Karin, 1999, How NF-kappaB is activated: The role of the IkappaB kinase (IKK) complex, Oncogene, 18, 6867, 10.1038/sj.onc.1203219 Kim, 1999, Apoptotic chondrocyte death in rheumatoid arthritis, Arthritis Rheum, 42, 1528, 10.1002/1529-0131(199907)42:7<1528::AID-ANR28>3.0.CO;2-9 Kuhn, 2000, IL-1 beta protects human chondrocytes from CD95-induced apoptosis, J Immunol, 164, 2233, 10.4049/jimmunol.164.4.2233 Lee, 2000, Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice, Science, 289, 2350, 10.1126/science.289.5488.2350 Loeser, 2000, Reduction in the chondrocyte response to insulin-like growth factor 1 in aging and osteoarthritis: Studies in a non-human primate model of naturally occurring disease, Arthritis Rheum, 43, 2110, 10.1002/1529-0131(200009)43:9<2110::AID-ANR23>3.0.CO;2-U Lotz, 1999, Mechanisms of chondrocyte apoptosis, Osteoarthritis Cartilage, 7, 389, 10.1053/joca.1998.0220 Makarov, 2001, NF-κB in rheumatoid arthritis: A pivotal regulator of inflammation, hyperplasia, and tissue destruction, Arthritis Res, 3, 200, 10.1186/ar300 Malicev, 2000, Vitamin C induced apoptosis in human articular chondrocytes, Pflugers Arch, 440, R46, 10.1007/s004240000001 McAdam, 2000, Effect of regulated expression of human cyclooxygenase isoforms on eicosanoid and isoeicosanoid production in inflammation, J Clin Invest, 105, 1473, 10.1172/JCI9523 Miagkov, 1998, NF-kappaB activation provides the potential link between inflammation and hyperplasia in the arthritic joint, Proc Natl Acad Sci USA, 95, 13859, 10.1073/pnas.95.23.13859 Ozes, 1999, NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase, Nature, 401, 82, 10.1038/43466 Pahl, 1999, Activators and target genes of Rel/NF-kappaB transcription factors, Oncogene, 18, 6853, 10.1038/sj.onc.1203239 Pierce, 1997, Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo, J Biol Chem, 272, 21096, 10.1074/jbc.272.34.21096 Reddy, 2000, Phosphatidylinositol 3-kinase as a mediator of TNF-induced NF-kappa B activation, J Immunol, 164, 1355, 10.4049/jimmunol.164.3.1355 Relic, 2001, IL-4 and IL-13, but not IL-10, protect human synoviocytes from apoptosis, J Immunol, 166, 2775, 10.4049/jimmunol.166.4.2775 Romashkova, 1999, NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling, Nature, 401, 86, 10.1038/43474 Sakai, 2001, Tumor necrosis factor alpha induces expression of genes for matrix degradation in human chondrocyte-like HCS-2/8 cells through activation of NF-kappaB: Abrogation of tumor necrosis factor alpha effect by proteasome inhibitors, J Bone Miner Res, 16, 1272, 10.1359/jbmr.2001.16.7.1272 Sakurai, 1995, Nitric oxide production and inducible nitric oxide synthase expression in inflammatory arthritides, J Clin Invest, 96, 2357, 10.1172/JCI118292 Shimada, 2000, Hepatocyte growth factor protects gastric epithelial cells against ceramide-induced apoptosis through induction of cyclooxygenase-2, Life Sci, 68, 539, 10.1016/S0024-3205(00)00959-0 Sizemore, 1999, Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit, Mol Cell Biol, 19, 4798, 10.1128/MCB.19.7.4798 Sonoda, 2000, Anti-apoptotic role of focal adhesion kinase (FAK): Induction of inhibitor-of-apoptosis proteins and apoptosis suppression by the overexpression of FAK in a human leukemic cell line, HL-60, J Biol Chem, 275, 16309, 10.1074/jbc.275.21.16309 Sovak, 1997, Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancer, J Clin Invest, 100, 2952, 10.1172/JCI119848 Susin, 2000, Two distinct pathways leading to nuclear apoptosis, J Exp Med, 192, 571, 10.1084/jem.192.4.571 Tardif, 1996, Normal expression of type 1 insulin-like growth factor receptor by human osteoarthritic chondrocytes with increased expression and synthesis of insulin-like growth factor binding proteins, Arthritis Rheum, 39, 968, 10.1002/art.1780390614 Wang, 2000, Tumor necrosis factor alpha-induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II, J Biol Chem, 275, 32592, 10.1074/jbc.M001358200 Weber, 2000, Suppression of NF-kappaB activity by sulfasalazine is mediated by direct inhibition of IkappaB kinases alpha and beta, Gastroenterology, 119, 1209, 10.1053/gast.2000.19458 Wu, 1996, Inhibition of NF-kappaB/Rel induces apoptosis of murine B cells, EMBO J, 15, 4682, 10.1002/j.1460-2075.1996.tb00845.x Yang, 1997, Apoptosis of chondrocytes in transgenic mice lacking collagen II, Exp Cell Res, 235, 370, 10.1006/excr.1997.3692