F. Carswell1, R. Hainsworth1, J. R. Ledsome1
1Cardiovascular Unit, Department of Physiology, School of Medicine, University of Leeds
Tóm tắt
An isolated kidney obtained from a donor dog was perfused at constant pressure with blood from the femoral artery of a recipient dog. The left atrial pressure of the recipient dog was increased by approximately 20 cm H20 by inflating a balloon in the left atrium. Left atrial distension caused an increase in urine flow and sodium excretion from the isolated perfused kidney and on a few occasions from the dog's own kidneys. The results support the view that a blood borne agent is responsible for the diuretic response to left atrial distension.
