TGF-β1 potentiates Vγ9Vδ2 T cell adoptive immunotherapy of cancer
Tài liệu tham khảo
Godder, 2007, Long term disease-free survival in acute leukemia patients recovering with increased gammadelta T cells after partially mismatched related donor bone marrow transplantation, Bone Marrow Transplant., 39, 751, 10.1038/sj.bmt.1705650
Gentles, 2015, The prognostic landscape of genes and infiltrating immune cells across human cancers, Nat. Med., 21, 938, 10.1038/nm.3909
Sebestyen, 2020, Translating gammadelta (γδ) T cells and their receptors into cancer cell therapies, Nat. Rev. Drug Discov., 19, 169, 10.1038/s41573-019-0038-z
Herrmann, 2020, An Update on the Molecular Basis of Phosphoantigen Recognition by Vγ9Vδ2 T Cells, Cells, 9, E1433, 10.3390/cells9061433
Xiang, 2017, Dual Face of Vγ9Vδ2-T Cells in Tumor Immunology: Anti- versus Pro-Tumoral Activities, Front. Immunol., 8, 1041, 10.3389/fimmu.2017.01041
Correia, 2013, Tumor cell recognition by γδ T lymphocytes: T-cell receptor vs. NK-cell receptors, OncoImmunology, 2, e22892, 10.4161/onci.22892
Maniar, 2010, Human gammadelta T lymphocytes induce robust NK cell-mediated antitumor cytotoxicity through CD137 engagement, Blood, 116, 1726, 10.1182/blood-2009-07-234211
Ismaili, 2002, Human gamma delta T cells induce dendritic cell maturation, Clin. Immunol., 103, 296, 10.1006/clim.2002.5218
Brandes, 2005, Professional antigen-presentation function by human gammadelta T Cells, Science, 309, 264, 10.1126/science.1110267
Rischer, 2004, Human gammadelta T cells as mediators of chimaeric-receptor redirected anti-tumour immunity, Br. J. Haematol., 126, 583, 10.1111/j.1365-2141.2004.05077.x
Kang, 2009, Adoptive immunotherapy of lung cancer with immobilized anti-TCRgammadelta antibody-expanded human gammadelta T-cells in peripheral blood, Cancer Biol. Ther., 8, 1540, 10.4161/cbt.8.16.8950
Fournié, 2013, What lessons can be learned from γδ T cell-based cancer immunotherapy trials?, Cell. Mol. Immunol., 10, 35, 10.1038/cmi.2012.39
Casetti, 2009, Cutting edge: TGF-beta1 and IL-15 Induce FOXP3+ gammadelta regulatory T cells in the presence of antigen stimulation, J. Immunol., 183, 3574, 10.4049/jimmunol.0901334
Ness-Schwickerath, 2010, Cytokine requirements for the differentiation and expansion of IL-17A- and IL-22-producing human Vgamma2Vdelta2 T cells, J. Immunol., 184, 7268, 10.4049/jimmunol.1000600
Peters, 2018, TGF-β enhances the cytotoxic activity of Vδ2 T cells, OncoImmunology, 8, e1522471, 10.1080/2162402X.2018.1522471
Peters, 2016, Human Vδ2 T cells are a major source of interleukin-9, Proc. Natl. Acad. Sci. USA, 113, 12520, 10.1073/pnas.1607136113
Batlle, 2019, Transforming Growth Factor-β Signaling in Immunity and Cancer, Immunity, 50, 924, 10.1016/j.immuni.2019.03.024
Schajnovitz, 2011, CXCL12 secretion by bone marrow stromal cells is dependent on cell contact and mediated by connexin-43 and connexin-45 gap junctions, Nat. Immunol., 12, 391, 10.1038/ni.2017
Merzaban, 2011, Analysis of glycoprotein E-selectin ligands on human and mouse marrow cells enriched for hematopoietic stem/progenitor cells, Blood, 118, 1774, 10.1182/blood-2010-11-320705
Fuhlbrigge, 1997, Cutaneous lymphocyte antigen is a specialized form of PSGL-1 expressed on skin-homing T cells, Nature, 389, 978, 10.1038/40166
Buckley, 2000, Persistent induction of the chemokine receptor CXCR4 by TGF-beta 1 on synovial T cells contributes to their accumulation within the rheumatoid synovium, J. Immunol., 165, 3423, 10.4049/jimmunol.165.6.3423
Franitza, 2002, TGF-beta1 enhances SDF-1alpha-induced chemotaxis and homing of naive T cells by up-regulating CXCR4 expression and downstream cytoskeletal effector molecules, Eur. J. Immunol., 32, 193, 10.1002/1521-4141(200201)32:1<193::AID-IMMU193>3.0.CO;2-H
Sackstein, 2004, The bone marrow is akin to skin: HCELL and the biology of hematopoietic stem cell homing, J. Invest. Dermatol., 122, 1061, 10.1111/j.0022-202X.2004.09301.x
Colonna-Romano, 2004, Impairment of gamma/delta T lymphocytes in elderly: implications for immunosenescence, Exp. Gerontol., 39, 1439, 10.1016/j.exger.2004.07.005
Schwartzkopff, 2015, TGF-β downregulates KLRG1 expression in mouse and human CD8(+) T cells, Eur. J. Immunol., 45, 2212, 10.1002/eji.201545634
Peters, 2018, Regulatory functions of γδ T cells, Cell. Mol. Life Sci., 75, 2125, 10.1007/s00018-018-2788-x
Dar, 2006, Mutual, reciprocal SDF-1/CXCR4 interactions between hematopoietic and bone marrow stromal cells regulate human stem cell migration and development in NOD/SCID chimeric mice, Exp. Hematol., 34, 967, 10.1016/j.exphem.2006.04.002
Sackstein, 2008, Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone, Nat. Med., 14, 181, 10.1038/nm1703
Man, 2019, In Vivo PET Tracking of 89Zr-Labeled Vγ9Vδ2 T Cells to Mouse Xenograft Breast Tumors Activated with Liposomal Alendronate, Mol. Ther., 27, 219, 10.1016/j.ymthe.2018.10.006
D’Asaro, 2010, V gamma 9V delta 2 T lymphocytes efficiently recognize and kill zoledronate-sensitized, imatinib-sensitive, and imatinib-resistant chronic myelogenous leukemia cells, J. Immunol., 184, 3260, 10.4049/jimmunol.0903454
Mattarollo, 2007, Chemotherapy and zoledronate sensitize solid tumour cells to Vgamma9Vdelta2 T cell cytotoxicity, Cancer Immunol. Immunother., 56, 1285, 10.1007/s00262-007-0279-2
Kabelitz, 2020, Cancer immunotherapy with γδ T cells: many paths ahead of us, Cell. Mol. Immunol., 17, 925, 10.1038/s41423-020-0504-x
Wu, 2014, γδT17 cells promote the accumulation and expansion of myeloid-derived suppressor cells in human colorectal cancer, Immunity, 40, 785, 10.1016/j.immuni.2014.03.013
Domcke, 2013, Evaluating cell lines as tumour models by comparison of genomic profiles, Nat. Commun., 4, 2126, 10.1038/ncomms3126
Richards, 2003, Prostaglandin E2 regulates aromatase activity and expression in human adipose stromal cells via two distinct receptor subtypes, J. Clin. Endocrinol. Metab., 88, 2810, 10.1210/jc.2002-021475
Truffinet, 2007, Cyclooxygenase-1, but not -2, in blast cells of patients with acute leukemia, Int. J. Cancer, 121, 924, 10.1002/ijc.22786
Capietto, 2010, Phosphoantigens overcome human TCRVgamma9+ gammadelta cell immunosuppression by TGF-beta: relevance for cancer immunotherapy, J. Immunol., 184, 6680, 10.4049/jimmunol.1000681
Biasco, 2021, Clonal expansion of T memory stem cells determines early anti-leukemic responses and long-term CAR T cell persistence in patients, Nat. Can., 2, 629, 10.1038/s43018-021-00207-7
Martinet, 2009, A regulatory cross-talk between Vgamma9Vdelta2 T lymphocytes and mesenchymal stem cells, Eur. J. Immunol., 39, 752, 10.1002/eji.200838812
Holen, 2010, Activation of EphA receptors on CD4+CD45RO+ memory cells stimulates migration, J. Leukoc. Biol., 87, 1059, 10.1189/jlb.0709497
Zenarruzabeitia, 2015, The Biology and Disease Relevance of CD300a, an Inhibitory Receptor for Phosphatidylserine and Phosphatidylethanolamine, J. Immunol., 194, 5053, 10.4049/jimmunol.1500304
Gabriel, 2021, Transforming growth factor-beta-regulated mTOR activity preserves cellular metabolism to maintain long-term T cell responses in chronic infection, Immunity, 54, 1698, 10.1016/j.immuni.2021.06.007
Wang, 2000, Different roles of the CD2 and LFA-1 T-cell co-receptors for regulating cytotoxic, proliferative, and cytokine responses of human V gamma 9/V delta 2 T cells, Mol. Med., 6, 196, 10.1007/BF03402114
Kawada, 1996, Clinical significance of LEA-1 expression in adult acute myeloid leukemia, Leuk. Res., 20, 327, 10.1016/0145-2126(95)00113-1
Bendall, 1995, GM-CSF enhances IL-2-activated natural killer cell lysis of clonogenic AML cells by upregulating target cell expression of ICAM-1, Leukemia, 9, 677
Whilding, 2019, CAR T-Cells Targeting the Integrin αvβ6 and Co-Expressing the Chemokine Receptor CXCR2 Demonstrate Enhanced Homing and Efficacy against Several Solid Malignancies, Cancers (Basel), 11, E674, 10.3390/cancers11050674
Zhao, 2014, A Comprehensive Analysis of CXCL12 Isoforms in Breast Cancer.., Transl. Oncol., 7, 429, 10.1016/j.tranon.2014.04.001
Mann, 2010, Identification of thioaptamer ligand against E-selectin: potential application for inflamed vasculature targeting, PLoS ONE, 5, e13050, 10.1371/journal.pone.0013050
Gu, 2014, Rapamycin together with TGF-β1, IL-2 and IL-15 induces the generation of functional regulatory γδT cells from human peripheral blood mononuclear cells, J. Immunol. Methods, 402, 82, 10.1016/j.jim.2013.11.009
Peters, 2014, Phenotype and regulation of immunosuppressive Vδ2-expressing γδ T cells, Cell. Mol. Life Sci., 71, 1943, 10.1007/s00018-013-1467-1
Kouakanou, 2020, Vitamin C supports conversion of human γδ T cells into FOXP3-expressing regulatory cells by epigenetic regulation, Sci. Rep., 10, 6550, 10.1038/s41598-020-63572-w
Tosolini, 2017, Assessment of tumor-infiltrating TCRVγ9Vδ2 γδ lymphocyte abundance by deconvolution of human cancers microarrays, OncoImmunology, 6, e1284723, 10.1080/2162402X.2017.1284723
Chen, 2014, Overexpression of IL-9 induced by STAT6 activation promotes the pathogenesis of chronic lymphocytic leukemia, Int. J. Clin. Exp. Pathol., 7, 2319
Gundermann, 2014, A comprehensive analysis of primary acute myeloid leukemia identifies biomarkers predicting susceptibility to human allogeneic Vγ9Vδ2 T cells, J. Immunother., 37, 321, 10.1097/CJI.0000000000000043
Parente-Pereira, 2020, Efficient ex vivo expansion of gamma delta T-cells from AML patients requires elimination of circulating leukemia blasts, Adv. Leuk. Res. Treat., 2, 28
Vyborova, 2020, γ9δ2T cell diversity and the receptor interface with tumor cells, J. Clin. Invest., 130, 4637, 10.1172/JCI132489
Ravens, 2020, Microbial exposure drives polyclonal expansion of innate γδ T cells immediately after birth, Proc. Natl. Acad. Sci. USA, 117, 18649, 10.1073/pnas.1922588117
Papadopoulou, 2020, Fetal public Vγ9Vδ2 T cells expand and gain potent cytotoxic functions early after birth, Proc. Natl. Acad. Sci. USA, 117, 18638, 10.1073/pnas.1922595117
Whilding, 2017, Targeting of Aberrant αvβ6 Integrin Expression in Solid Tumors Using Chimeric Antigen Receptor-Engineered T Cells, Mol. Ther., 25, 259, 10.1016/j.ymthe.2016.10.012
Parente-Pereira, 2014, Use of retroviral-mediated gene transfer to deliver and test function of chimeric antigen receptors in human T-cells, J. Biol. Methods, 1, e7, 10.14440/jbm.2014.30
Bolger, 2014, Trimmomatic: a flexible trimmer for Illumina sequence data, Bioinformatics, 30, 2114, 10.1093/bioinformatics/btu170
Kim, 2015, HISAT: a fast spliced aligner with low memory requirements, Nat. Methods, 12, 357, 10.1038/nmeth.3317
Yates, 2020, Ensembl 2020, Nucleic Acids Res., 48, D682
Anders, 2015, HTSeq--a Python framework to work with high-throughput sequencing data, Bioinformatics, 31, 166, 10.1093/bioinformatics/btu638
Love, 2014, Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2, Genome Biol., 15, 550, 10.1186/s13059-014-0550-8
Benjamini, 1995, Controlling the false discovery rate: a practical and powerful approach to multiple testing, J. R. Stat. Soc. B, 57, 289
Strimmer, 2008, A unified approach to false discovery rate estimation, BMC Bioinformatics, 9, 303, 10.1186/1471-2105-9-303
Goldman, 2020, Visualizing and interpreting cancer genomics data via the Xena platform, Nat. Biotechnol., 38, 675, 10.1038/s41587-020-0546-8
Subramanian, 2005, Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles, Proc. Natl. Acad. Sci. USA, 102, 15545, 10.1073/pnas.0506580102
Liberzon, 2011, Molecular signatures database (MSigDB) 3.0, Bioinformatics, 27, 1739, 10.1093/bioinformatics/btr260
Wickham, 2017
Schneider, 2012, NIH Image to ImageJ: 25 years of image analysis, Nat. Methods, 9, 671, 10.1038/nmeth.2089
Andrews, S. (2010). FastQC: A Quality Control Tool for High Throughput Sequence Data [Online]. Available online at: http://www.bioinformatics.babraham.ac.uk/projects/fastqc/, accessed December 8th, 2021.
Nagy, 2021, Pancancer survival analysis of cancer hallmark genes, Sci Rep, 11, 6047, 10.1038/s41598-021-84787-5
Mootha, 2003, PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes, Nat. Genet., 34, 267, 10.1038/ng1180
