TEMPERATURE-SENSITIVE MUTATIONS IN DROSOPHILA MELANOGASTER.: II. FREQUENCY AMONG SECOND CHROMOSOME RECESSIVE LETHALS INDUCED BY ETHYL METHANESULFONATE

Canadian Science Publishing - Tập 10 Số 2 - Trang 412-420 - 1968
David L. Baillie, David T Suzuki, Mary Tarasoff

Tóm tắt

Recessive lethal and semilethal mutations induced in chromosome 2 by ethyl methanesulfonate were screened for temperature-sensitivity. Mutants which survive at 17 °C but die at 29° were recovered. At 0.005M EMS, 37.5% of the treated chromosomes were found to be lethal or semilethal from which it is estimated that 10.9% of all EMS-induced lethals are ts. This class of conditional lethals promises to be a useful tool in genetic studies.

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