TDP-43 plasma levels do not differentiate sporadic inclusion body myositis from other inflammatory myopathies

H. Bea Kuiperij1, Wilson F. Abdo1, Baziel G. van Engelen1, Helenius J. Schelhaas1, Marcel M. Verbeek1
1Department of Neurology, Donders Institute for Brain Cognition and Behaviour, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

Tóm tắt

Từ khóa


Tài liệu tham khảo

Abdo WF, van Mierlo T, Hengstman GJ, Schelhaas HJ, van Engelen BG, Verbeek MM (2009) Increased plasma amyloid-beta42 protein in sporadic inclusion body myositis. Acta Neuropathol 118:429–431

Foulds P, McAuley E, Gibbons L et al (2008) TDP-43 protein in plasma may index TDP-43 brain pathology in Alzheimer’s disease and frontotemporal lobar degeneration. Acta Neuropathol 116:141–146

Foulds PG, Davidson Y, Mishra M et al (2009) Plasma phosphorylated-TDP-43 protein levels correlate with brain pathology in frontotemporal lobar degeneration. Acta Neuropathol 118:647–658

Kasai T, Tokuda T, Ishigami N et al (2009) Increased TDP-43 protein in cerebrospinal fluid of patients with amyotrophic lateral sclerosis. Acta Neuropathol 117:55–62

Küsters B, van Hoeve BJ, Schelhaas HJ, Ter Laak H, van Engelen BG, Lammens M (2009) TDP-43 accumulation is common in myopathies with rimmed vacuoles. Acta Neuropathol 117:209–211

Olive M, Janue A, Moreno D, Gamez J, Torrejon-Escribano B, Ferrer I (2009) TAR DNA-binding protein 43 accumulation in protein aggregate myopathies. J Neuropathol Exp Neurol 68:262–273

Weihl CC, Temiz P, Miller SE et al (2008) TDP-43 accumulation in inclusion body myopathy muscle suggests a common pathogenic mechanism with frontotemporal dementia. J Neurol Neurosurg Psychiatry 79:1186–1189