TCM grammar systems: An approach to aid the interpretation of the molecular interactions in Chinese herbal medicine

Adane, 2010, Binding modes of 2,4-diaminoquinazoline and 2,4-diaminopteridine analogs to P. falciparum dihydrofolate reductase enzyme: molecular docking studies, Indian Journal of Pharmaceutical Sciences, 72, 324, 10.4103/0250-474X.70478 AI-Sayah, 2008, High throughput screening of active pharmaceutical ingredients by UPLC, Journal of Separation Science, 31, 2167, 10.1002/jssc.200700594 Barton, R.H., 2011. A decade of advances in metabonomics. Expert Opinion on Drug Metabolism & Toxicology (Epub ahead of print). Bonizzi, 2004, The two NF-kappaB activation pathways and their role in innate and adaptive immunity, Trends in Immunology, 25, 758, 10.1016/j.it.2004.03.008 Boyce, 2008, Eicosanoids in asthma, allergic inflammation, and host defense, Current Molecular Medicine, 8, 335, 10.2174/156652408785160989 Cao, 2006, Expression of epidermal growth factor receptor and its ligands in chronic asthma mice and the influence of dexamethasone, Journal of the Fourth Military Medical University, 562, 216 Chen, 2002, TNF-R1 signaling: a beautiful pathway, Science, 296, 1634, 10.1126/science.1071924 Chen, 2006, CD40/CD40L dyad in the inflammatory and immune responses in the central nervous system, Cellular & Molecular Immunology, 3, 163 Deng, 2008, Pharmacophore modelling and virtual screening for identification of new Aurora: a kinase inhibitors, Chemical Biology & Drug Design, 71, 533, 10.1111/j.1747-0285.2008.00663.x Deng, 2000, Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain, Cell, 103, 351, 10.1016/S0092-8674(00)00126-4 Duroudier, 2009, Leukotriene pathway genetics and pharmacogenetics in allergy, Allergy, 64, 823, 10.1111/j.1398-9995.2009.02015.x Gately, 1998, The interleukin-12/interleukin-12-receptor system: role in normal and athologic immune responses, Annual Review of Immunology, 16, 495, 10.1146/annurev.immunol.16.1.495 Habu, 2001, Themechanism of a defective IFN-gamma response to bacterial toxins in an atopic dermatitismode, l NC/Ngamice, and the therapeutic effect of IFN-gamma, IL-12, or IL-18 on dermatitis, Immunology, 166, 5439, 10.4049/jimmunol.166.9.5439 Idris, 2001, Protein kinase C activation: isozyme-specific effects on metabolism and cardiovascular complications in diabetes, Diabetologia, 44, 84, 10.1007/s001250051675 Jeon, 2004, Essential role of the E3 ubiquitin ligase Cbl-b in T cell anergy induction, Immunity, 21, 167, 10.1016/j.immuni.2004.07.013 Kawashima, 1998, Interleukin-12 induces tyrosine phosphorylation of an 85-kDa protein associated with the interleukin-12 receptor beta 1 subunit, Cellular Immunology, 186, 39, 10.1006/cimm.1998.1294 Kodama, 2003, Role of interleukin-12 in the regulation of CD4+T cell apoptosis in amousemodel of asthma, Clinical and Experimental Immunology, 131, 199, 10.1046/j.1365-2249.2003.02073.x Kuhn, 2010, STITCH 2: an interaction network database for small molecules and proteins, Nucleic Acids, 552, 37 Liu, 2005, Studies on compatibility principal of HED-effects and mechanism of the compatibility of HED anti-inflammation and anti-allergic asthma, Chinese Traditional Patent Medicine, 27, 345 Liu, 2007, Effects of among compositions of Herba Ephedrae decoction on genic expression of 5-lipoxygenase activating protein IL-4 and leukotriene C4 in asthmatic mice, China Journal of Chinese Material Medical, 32, 246 Major, 2010, Calcium-dependent conformational flexibility of a CUB domain controls activation of the complement serine protease C1r, Journal of Biological Chemistry, 285, 11863, 10.1074/jbc.M109.098541 Min, 2001, Traditional Chinese medicine database and application on the web, American Chemical Society, 41, 273 Nadanaciva et al., 2010. A high content screening assay for identifying lysosomotropic compounds. Toxicology in Vitro (Epub ahead of print). Oess, 2006, Subcellular targeting and trafficking of nitric oxide synthases, Biochemical Journal, 396, 401, 10.1042/BJ20060321 Paul, 2003, Cytoscape: a software environment for integrated models of biomolecular interaction networks, Genome Research, 13, 2498, 10.1101/gr.1239303 Van, 2009, Systems biology guided by Chinese medicine reveals new markers for sub-typing rheumatoid arthritis patients, Journal of Clinical Rheumatology, 15, 330, 10.1097/RHU.0b013e3181ba3926 Vizcaíno, 2010, The proteomics identifications database: 2010 update, Nucleic Acids, 736, 80 Wang, 2004, Entity grammar systems: a grammatical tool for studying the hierarchal structures of biological systems, Bulletin of Mathematical Biology, 66, 447, 10.1016/j.bulm.2003.08.011 Wang, 2007, vol. 4490 Wenzel-Seifert, 2002, Similarities and differences in the coupling of human beta1- and beta2-adrenoceptors to Gs(alpha) splice variants, Biochemical Pharmacology, 64, 9, 10.1016/S0006-2952(02)00924-3 Zhang, 2007, A novel class of anti-inflammatory and analgesic drugs – no-donating NSAIDs, Acta Pharmaceutica Sinica, 42, 352