TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging
Daichao Xu1, Taijie Jin2,3, Hong Zhu1, Hongbo Chen1, Dimitry Ofengeim1, Chengyu Zou1, Lauren Mifflin1, Lifeng Pan4, Palak Amin1, Wanjin Li1, Bing Shan2, Masanori Gomi Naito1, Huyan Meng2,3, Ying Li2, Heling Pan2, Liviu Aron5, Xian Adiconis6, Joshua Z. Levin6, Bruce A. Yankner5, Junying Yuan1,2
1Department of Cell Biology, Harvard Medical School, 240 Longwood Ave., Boston, MA 02115, USA
2Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 26 Qiuyue Rd., Pudong, 201210 Shanghai, China
3University of Chinese Academy of Sciences, 100049 Beijing, China
4Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Rd., 200032 Shanghai, China
5Department of Genetics, Harvard Medical School, Boston, MA 02115, USA
6Broad Institute, Cambridge, MA 02142, USA