Synthetic human embryology: towards a quantitative future

Current Opinion in Genetics & Development - Tập 63 - Trang 30-35 - 2020
Yue Shao1, Jianping Fu2,3,4
1Institute of Biomechanics and Medical Engineering, Department of Engineering Mechanics, School of Aerospace Engineering, Tsinghua University, Beijing 100084, China
2Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109, USA
3Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, 48109, USA
4Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA

Tài liệu tham khảo

Deglincerti, 2016, Self-organization of the in vitro attached human embryo, Nature, 533, 251, 10.1038/nature17948 Shahbazi, 2016, Self-organization of the human embryo in the absence of maternal tissues, Nat Cell Biol, 18, 700, 10.1038/ncb3347 Xiang, 2020, A developmental landscape of 3D-cultured human pre-gastrulation embryos, Nature, 577, 537, 10.1038/s41586-019-1875-y Hyun, 2016, Embryology policy: revisit the 14-day rule, Nature, 533, 169, 10.1038/533169a Harrison, 2017, Assembly of embryonic and extraembryonic stem cells to mimic embryogenesis in vitro, Science, 356, 10.1126/science.aal1810 Niu, 2019, Dissecting primate early post-implantation development using long-term in vitro embryo culture, Science, 366, 10.1126/science.aaw5754 Ma, 2019, In vitro culture of cynomolgus monkey embryos beyond early gastrulation, Science, 366, 10.1126/science.aax7890 Bedzhov, 2014, Self-organizing properties of mouse pluripotent cells initiate morphogenesis upon implantation, Cell, 156, 1032, 10.1016/j.cell.2014.01.023 McDole, 2018, In toto imaging and reconstruction of post-implantation mouse development at the single-cell level, Cell, 175, 859, 10.1016/j.cell.2018.09.031 Rossant, 2015, Mouse and human blastocyst-derived stem cells: vive les differences, Development, 142, 9, 10.1242/dev.115451 Nakamura, 2016, A developmental coordinate of pluripotency among mice, monkeys and humans, Nature, 537, 57, 10.1038/nature19096 Mora-Bermudez, 2016, Differences and similarities between human and chimpanzee neural progenitors during cerebral cortex development, eLife, 5, 10.7554/eLife.18683 Sasaki, 2016, The germ cell fate of cynomolgus monkeys is specified in the nascent amnion, Dev Cell, 39, 169, 10.1016/j.devcel.2016.09.007 Taniguchi, 2015, Lumen formation is an intrinsic property of isolated human pluripotent stem cells, Stem Cell Rep, 5, 954, 10.1016/j.stemcr.2015.10.015 Taniguchi, 2017, An apicosome initiates self-organizing morphogenesis of human pluripotent stem cells, J Cell Biol, 216, 3981, 10.1083/jcb.201704085 Shahbazi, 2017, Pluripotent state transitions coordinate morphogenesis in mouse and human embryos, Nature, 552, 239, 10.1038/nature24675 Ryan, 2019, Lumen expansion facilitates epiblast-primitive endoderm fate specification during mouse blastocyst formation, Dev Cell, 51, 684, 10.1016/j.devcel.2019.10.011 Shao, 2017, Self-organized amniogenesis by human pluripotent stem cells in a biomimetic implantation-like niche, Nat Mater, 16, 419, 10.1038/nmat4829 Shao, 2017, A pluripotent stem cell-based model for post-implantation human amniotic sac development, Nat Commun, 8, 208, 10.1038/s41467-017-00236-w Zheng, 2019, Controlled modelling of human epiblast and amnion development using stem cells, Nature, 573, 421, 10.1038/s41586-019-1535-2 Esfahani, 2019, Microengineered human amniotic ectoderm tissue array for high-content developmental phenotyping, Biomaterials, 216 Warmflash, 2014, A method to recapitulate early embryonic spatial patterning in human embryonic stem cells, Nat Methods, 11, 847, 10.1038/nmeth.3016 Deglincerti, 2016, Self-organization of human embryonic stem cells on micropatterns, Nat Protoc, 11, 2223, 10.1038/nprot.2016.131 Martyn, 2018, Self-organization of a human organizer by combined Wnt and Nodal signalling, Nature, 558, 132, 10.1038/s41586-018-0150-y Simunovic, 2019, A 3D model of a human epiblast reveals BMP4-driven symmetry breaking, Nat Cell Biol, 21, 900, 10.1038/s41556-019-0349-7 Chhabra, 2019, Dissecting the dynamics of signaling events in the BMP, WNT, and NODAL cascade during self-organized fate patterning in human gastruloids, PLoS Biol, 17, 10.1371/journal.pbio.3000498 Nemashkalo, 2017, Morphogen and community effects determine cell fates in response to BMP4 signaling in human embryonic stem cells, Development, 144, 3042 Etoc, 2016, A balance between secreted inhibitors and edge sensing controls gastruloid self-organization, Dev Cell, 39, 302, 10.1016/j.devcel.2016.09.016 Martyn, 2019, A wave of WNT signaling balanced by secreted inhibitors controls primitive streak formation in micropattern colonies of human embryonic stem cells, Development, 146 Tewary, 2019, High-throughput micropatterning platform reveals Nodal-dependent bisection of peri-gastrulation-associated versus preneurulation-associated fate patterning, PLoS Biol, 17, 10.1371/journal.pbio.3000081 Heemskerk, 2019, Rapid changes in morphogen concentration control self-organized patterning in human embryonic stem cells, eLife, 8, 10.7554/eLife.40526 Massey, 2019, Synergy with TGF beta ligands switches WNT pathway dynamics from transient to sustained during human pluripotent cell differentiation, Proc Natl Acad Sci U S A, 116, 4989, 10.1073/pnas.1815363116 Kondo, 2010, Reaction-diffusion model as a framework for understanding biological pattern formation, Science, 329, 1616, 10.1126/science.1179047 Xue, 2018, Mechanics-guided embryonic patterning of neuroectoderm tissue from human pluripotent stem cells, Nat Mater, 17, 633, 10.1038/s41563-018-0082-9 Chambers, 2009, Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling, Nat Biotechnol, 27, 275, 10.1038/nbt.1529 Chambers, 2012, Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors, Nat Biotechnol, 30, 715, 10.1038/nbt.2249 Lee, 2007, Isolation and directed differentiation of neural crest stem cells derived from human embryonic stem cells, Nat Biotechnol, 25, 1468, 10.1038/nbt1365 Haremaki, 2019, Self-organizing neuruloids model developmental aspects of Huntington’s disease in the ectodermal compartment, Nat Biotechnol, 37, 1198, 10.1038/s41587-019-0237-5 Britton, 2019, A novel self-organizing embryonic stem cell system reveals signaling logic underlying the patterning of human ectoderm, Development, 146 Li, 2005, Specification of motoneurons from human embryonic stem cells, Nat Biotechnol, 23, 215, 10.1038/nbt1063 Ogura, 2018, Three-dimensional induction of dorsal, intermediate and ventral spinal cord tissues from human pluripotent stem cells, Development, 145, 10.1242/dev.162214 Zheng, 2019, Dorsal-ventral patterned neural cyst from human pluripotent stem cells in a neurogenic niche, Sci Adv, 5, 10.1126/sciadv.aax5933 Marklund, 2014, Detailed expression analysis of regulatory genes in the early developing human neural tube, Stem Cells Dev, 23, 5, 10.1089/scd.2013.0309 Meinhardt, 2014, 3D reconstitution of the patterned neural tube from embryonic stem cells, Stem Cell Rep, 3, 987, 10.1016/j.stemcr.2014.09.020 Ranga, 2016, Neural tube morphogenesis in synthetic 3D microenvironments, Proc Natl Acad Sci U S A, 113, E6831, 10.1073/pnas.1603529113 Yang, 2017, Derivation of pluripotent stem cells with in vivo embryonic and extraembryonic potency, Cell, 169, 243, 10.1016/j.cell.2017.02.005 Okae, 2018, Derivation of human trophoblast stem cells, Cell Stem Cell, 22, 50, 10.1016/j.stem.2017.11.004 Wamaitha, 2015, Gata6 potently initiates reprograming of pluripotent and differentiated cells to extraembryonic endoderm stem cells, Gene Dev, 29, 1239, 10.1101/gad.257071.114 Turco, 2018, Trophoblast organoids as a model for maternal-fetal interactions during human placentation, Nature, 564, 263, 10.1038/s41586-018-0753-3 Beccari, 2018, Multi-axial self-organization properties of mouse embryonic stem cells into gastruloids, Nature, 562, 272, 10.1038/s41586-018-0578-0 Rivron, 2018, Blastocyst-like structures generated solely from stem cells, Nature, 557, 106, 10.1038/s41586-018-0051-0 Zhang, 2019, Implantation initiation of self-assembled embryo-like structures generated using three types of mouse blastocyst-derived stem cells, Nat Commun, 10, 496, 10.1038/s41467-019-08378-9 Sozen, 2019, Self-Organization of mouse stem cells into an extended potential blastoid, Dev Cell, 51, 698, 10.1016/j.devcel.2019.11.014 Li, 2019, Generation of blastocyst-like structures from mouse embryonic and adult cell cultures, Cell, 179, 687, 10.1016/j.cell.2019.09.029 Rivron, 2018, Debate ethics of embryo models from stem cells, Nature, 564, 183, 10.1038/d41586-018-07663-9