Synthesis of substituted octahydrochromeno[3,2-i]quinazoline-2(1H)-thiones
Tóm tắt
Condensation of 8-arylidenehexahydroquinazoline-2-thiones with di- and trihydroxybenzenes affords the new heterocyclic system, viz., octahydrochromeno[3,2-i]quinazoline-2(1H)-thiones, in which the substituents in both the chromane and quinazoline rings can be varied over a wide range.
Tài liệu tham khảo
G. P. Ellis and I. M. Lockhart, The Chemistry of Heterocyclic Compounds, J. Wiley—Interscience, New York, 1981, 36.
G. W. Burton and K. U. Ingold, Acc. Chem. Res., 1986, 19, 194.
D. J. Brown, Comprehensive Heterocyclic Chemistry, Ed. A. R. Katritzky, Pergamon, Oxford, 1997, 3, 148.
H. I. El-Subbagh, S. M. Abu-Zaid, M. A. Mahran, F. A. Badria, and A. M. Al-Obaid, J. Med. Chem., 2000, 43, 2915.
S. I. Filimonov and E. I. Vaganova, Khim. Geterotsikl. Soedin., 2003, 263 [Chem. Heterocycl. Compd., 2003, 39 (Engl. Transl.)].