Sunita Bhagat1, Nutan Sharma1, Tejpal Singh Chundawat1
1Organic Synthesis Research Laboratory, Department of Chemistry, A.R.S.D. College, University of Delhi, New Delhi 110021
Tóm tắt
A new efficient and environmental friendly procedure for the synthesis of a series of salicylaldehyde‐based schiff bases under microwave irradiation is described. The method is compared with the conventional method also. The present work involves condensation of salicylaldehyde with various aromatic amines in water under microwave irradiation. A judicious choice of the solvent and reaction conditions allowed the final products to be generated in excellent yields in a one‐step procedure, whereas experiments under thermal conditions led to lower yields with tedious work‐up. Microwave irradiation method gives advantages like reduction in reaction time, increase in conversion, reduced wastes, and good yields. The structures of synthesized compounds were confirmed by IR, 1HNMR, and Mass Spectra data.
