Synthesis and evaluation of 4′,5′-dihydrospiro[piperidine-4,7′-thieno[2,3-c]pyran] analogues against both active and dormant Mycobacterium tuberculosis

Wirth, 2008, PLoS Pathog, 4, 10.1371/journal.ppat.1000160 Gagneux, 2012, Philos Trans R Soc Lond B Biol Sci, 367, 850, 10.1098/rstb.2011.0316 Frith, 2014, J Mil Veter Health, 22, 29 Hauck, 2009, Am Fam Physician, 79, 10 World Health Organization. Global Tuberculosis Report 2016. van den Boogaard, 2009, Antimicrob Agents Chemother, 53, 849, 10.1128/AAC.00749-08 Liebert, 2010, Expert Rev Anti Infect Ther, 8, 801, 10.1586/eri.10.60 Ballell, 2013, ChemMedChem, 8, 313, 10.1002/cmdc.201200428 Dhayalan, 2015, Synthesis, 47, 3972, 10.1055/s-0035-1560187 Bhattacharyya, 2014, RSC Adv, 4, 18229, 10.1039/c4ra01915f DeBaillie, 2014, Org Process Res Dev, 19, 1568, 10.1021/op5000094 Palomino, 2002, Antimicrob Agents Chemother, 46, 2720, 10.1128/AAC.46.8.2720-2722.2002 Betts, 2002, Mol Microbiol, 43, 717, 10.1046/j.1365-2958.2002.02779.x Devi, 2015, Tuberculosis, 95, 786, 10.1016/j.tube.2015.04.010 Tripathi, 2006, Acta Crystallogr Sect F Struct Biol Crystal Commun, 62, 572, 10.1107/S1744309106016824 Gerlier, 1986, Immunol Methods, 94, 57, 10.1016/0022-1759(86)90215-2