Synthesis and characterization of some novel 7-(aryl)-3-phenyl-6-(1H-tetrazol-5-yl)-5H-thiazolo[3,2-a]pyrimidin-5-one derivatives

Russian Journal of General Chemistry - Tập 87 - Trang 1618-1620 - 2017
N. M. Khalifa1,2, M. A. Al-Omar1, A. E. Amr1,3
1Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy, King Saud University, Riyadh, Saudi Arabia
2Department of Therapeutical Chemistry, Pharmaceutical and Drug Industries Division, National Research Centre, Dokki, Cairo, Egypt
3Applied Organic Chemistry Department, National Research Centre, Dokki, Cairo, Egypt

Tóm tắt

A series of novel tetrazole derivatives containing fused thiazolo[3,2-a]pyrimidines were synthesized in a one-pot three-component reaction of 7-(aryl)-5-oxo-3-phenyl-5H-thiazolo[3,2-a]pyrimidine-6-carbonitriles with sodium azide and ammonium chloride.

Tài liệu tham khảo

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