Synergistic Effects of Pesticides and Metals on the Fibrillation of α-Synuclein: Implications for Parkinson’s Disease
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Altschuler, 1999, Aluminum-containing antacids as a cause of idiopathic Parkinson’s disease, Med. Hypotheses, 53, 22, 10.1054/mehy.1997.0701
Conway, 1998, Accelerated in vitro fibril formation by a mutant α-synuclein linked to early-onset Parkinson disease, Nat. Med., 4, 1318, 10.1038/3311
Conway, 2000, Acceleration of oligomerization, not fibrillization, is a shared property of both α-synuclein mutations linked to early-onset Parkinson’s disease: implications for pathogenesis and therapy, Proc. Natl. Acad. Sci. U.S.A., 97, 571, 10.1073/pnas.97.2.571
Crowther, 1998, Synthetic filaments assembled from C-terminally truncated α-synuclein, FEBS Lett., 436, 309, 10.1016/S0014-5793(98)01146-6
El-Agnaf, 1998, Effects of the mutations Ala(30) to Pro and Ala(53) to Thr on the physical and morphological properties of α-synuclein protein implicated in Parkinson’s disease, FEBS Lett., 440, 67, 10.1016/S0014-5793(98)01419-7
Eliezer, 2001, Conformational properties of α-synuclein in its free and lipid-associated states, J. Mol. Biol., 307, 1061, 10.1006/jmbi.2001.4538
Fink, 1994, Classification of acid denaturation of proteins—intermediates and unfolded states, Biochemistry, 33, 12504, 10.1021/bi00207a018
Fink, 1998, Discrete intermediates versus molten globule models for protein folding: characterization of partially folded intermediates of apomyoglobin, Fold Des., 3, 19, 10.1016/S1359-0278(98)00005-4
Goedert, 2001, Parkinson’s disease and other α-synucleinopathies, Clin. Chem. Lab. Med., 39, 308, 10.1515/CCLM.2001.047
Good, 1992, Neuromelanin-containing neurons of the substantia nigra accumulate iron and aluminum in Parkinson’s disease: a LAMMA study, Brain Res., 593, 343, 10.1016/0006-8993(92)91334-B
Gorell, 1999, Occupational exposure to manganese, copper, lead, iron, mercury and zinc and the risk of Parkinson’s disease, Neurotoxicology, 20, 239
Goto, 1990, Acid-induced folding of proteins, Proc. Natl. Acad. Sci. U.S.A., 87, 573, 10.1073/pnas.87.2.573
Goto, 1990, Mechanism of acid-induced folding of proteins, Biochemistry, 29, 3480, 10.1021/bi00466a009
Hashimoto, 1998, Human recombinant NACP/α-synuclein is aggregated and fibrillated in vitro: Relevance for Lewy body disease, Brain Res., 799, 301, 10.1016/S0006-8993(98)00514-9
Hashimoto, 1999, Oxidative stress induces amyloid-like aggregate formation of NACP/α-synuclein in vitro, Neuroreport, 10, 717, 10.1097/00001756-199903170-00011
Hashimoto, 2001, β-Synuclein inhibits α-synuclein aggregation. A possible role as an anti-Parkinsonian factor, Neuron, 32, 213, 10.1016/S0896-6273(01)00462-7
Hellenbrand, 1996, Diet and Parkinson’s disease. II. A possible role for the past intake of specific nutrients. Results from a self-administered food-frequency questionnaire in a case–control study, Neurology, 47, 644, 10.1212/WNL.47.3.644
Hertzman, 1994, A case-control study of Parkinson’s disease in a horticultural region of British Columbia, Mov. Disord., 9, 69, 10.1002/mds.870090111
Hirsch, 1991, Iron and aluminum increase in the substantia nigra of patients with Parkinson’s disease: an X-ray microanalysis, J. Neurochem., 56, 446, 10.1111/j.1471-4159.1991.tb08170.x
Iwatsubo, 1996, Purification and characterization of Lewy bodies from the brains of patients with diffuse Lewy body disease, Am. J. Pathol., 148, 1517
Jakes, 1999, Epitope mapping of LB509, a monoclonal antibody directed against human α-synuclein, Neurosci. Lett., 269, 13, 10.1016/S0304-3940(99)00411-5
Li, 2001, Effect of familial Parkinson’s disease point mutations A30P and A53T on the structural properties, aggregation, and fibrillation of human α-synuclein, Biochemistry, 40, 11604, 10.1021/bi010616g
Manning-Bog, 2002, The herbicide paraquat causes up-regulation and aggregation of α-synuclein in mice. Paraquat and α-synuclein, J. Biol. Chem., 277, 1641, 10.1074/jbc.C100560200
Manning-Bog, 2002, The herbicide paraquat causes up-regulation and aggregation of α-synuclein in mice. Paraquat and α-synuclein, J. Biol. Chem., 277, 1641, 10.1074/jbc.C100560200
Naiki, 1989, Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, thioflavin T1, Anal. Biochem., 177, 244, 10.1016/0003-2697(89)90046-8
Naiki, 1990, Fluorometric examination of tissue amyloid fibrils in murine senile amyloidosis: use of the fluorescent indicator, thioflavine T, Lab. Invest., 62, 768
Narhi, 1999, Both familial Parkinson’s disease mutations accelerate α-synuclein aggregation, J. Biol. Chem., 274, 9843, 10.1074/jbc.274.14.9843
Shi, 1994, Protein conformational changes induced by 1,1′-bis(4-anilino-5-naphthalenesulfonic acid)—preferential binding to the molten globule of dnak, Biochemistry, 33, 7536, 10.1021/bi00190a006
Spillantini, 1998, α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson’s disease and dementia with Lewy bodies, Proc. Natl. Acad. Sci. U.S.A., 95, 6469, 10.1073/pnas.95.11.6469
Tanner, 1989, The role of environmental toxins in the etiology of Parkinson’s disease, Trends Neurosci., 12, 49, 10.1016/0166-2236(89)90135-5
Tanner, 1999, Parkinson disease in twins: an etiologic study, JAMA, 281, 341, 10.1001/jama.281.4.341
Uversky, 1998, Anion-induced folding of staphylococcal nuclease: characterization of multiple equilibrium partially folded intermediates, J. Mol. Biol., 278, 879, 10.1006/jmbi.1998.1741
Uversky, 2000, Why are “natively unfolded” proteins unstructured under physiologic conditions?, Proteins, 41, 415, 10.1002/1097-0134(20001115)41:3<415::AID-PROT130>3.0.CO;2-7
Uversky, 2001, Stabilization of partially folded conformation during α-synuclein oligomerization in both purified and cytosolic preparations, J. Biol. Chem., 276, 43495, 10.1074/jbc.C100551200
Uversky, 2001, Evidence for a partially folded intermediate in α-synuclein fibril formation, J. Biol. Chem., 276, 10737, 10.1074/jbc.M010907200
Uversky, 2001, Metal-triggered structural transformations, aggregation, and fibrillation of human α-synuclein. A possible molecular link between Parkinson’s disease and heavy metal exposure, J. Biol. Chem., 276, 44284, 10.1074/jbc.M105343200
Uversky, 2001, Pesticides directly accelerate the rate of α-synuclein fibril formation: a possible factor in Parkinson’s disease, FEBS Lett., 500, 105, 10.1016/S0014-5793(01)02597-2
Weinreb, 1996, NACP, a protein implicated in Alzheimer’s disease and learning, is natively unfolded, Biochemistry, 35, 13709, 10.1021/bi961799n
Yasui, 1992, Calcium, magnesium and aluminum concentrations in Parkinson’s disease, Neurotoxicology, 13, 593