Switching Methadone: A 10-Year Experience of 345 Patients in an Acute Palliative Care Unit

Pain Medicine - Tập 13 Số 3 - Trang 399-404 - 2012
Sebastiano Mercadante1,2
1Pain Relief and Palliative Care Unit, La Maddalena Cancer Center, Palermo
2Palliative Medicine, University of Palermo, Palermo, Italy

Tóm tắt

Từ khóa


Tài liệu tham khảo

Cherny N Ripamonti C Pereira J ; Expert Working Group of the European Association of Palliative Care Network. Strategies to manage the adverse effects of oral morphine: An evidence-based report. J Clin Oncol 2001;19:2542–54.

Mercadante S Bruera E . Opioid switching: A systematic and critical review. Cancer Treat Rev 2006;32:304–15.

Weschules D Bain K . A systematic review of opioid conversion ratios used with methadone for the treatment of pain. Pain Med 2008;9:595–612.

Quigley C . Opioid switching to improve pain relief and drug tolerability. Cochrane Database Syst Rev 2004;(3):CD004847.

Knotkova H Fine P Portenoy RK . Opioid rotation: The science and the limitations of the equianalgesic dose table. J Pain Symptom Manage 2009;38:426–39.

Slatkin N . Opioid switching and rotation in primary care: Implementation and clinical utility. Curr Med Res Opin 2009;25:2133–59.

Mercadante S Casuccio A Calderone L . Rapid switching from morphine to methadone in cancer patients with poor response to morphine. J Clin Oncol 1999;17:3307–12.

Mercadante S Villari P Ferrera P . A model of acute symptom control unit: Pain Relief and Palliative Care Unit of La Maddalena Cancer Center. Support Care Cancer 2003;11:114–9.

Mercadante S Intravaia G Villari P Clinical and financial analysis of an acute palliative care unit in an oncological department. Palliat Med 2008;22:760–7.

Mercadante S Ferrera P Villari P Frequency, indications, outcome, and predictive factors of opioid switching in an acute palliative care unit. J Pain Symptom Manage 2009;37:632–41.

Gonzalez-Barboteo J Porta-Sales J Sanchez D Tuca A Gomez-Batiste X . Conversion from parenteral to oral methadone. J Pain Palliat Care Pharmacother 2008;22:200–5.

Mercadante S Ferrera P Arcuri E . The use of fentanyl buccal tablets as breakthrough medication in patients receiving chronic methadone therapy: An open label preliminary study. Support Care Cancer 2011;19:435–8.

Bruera E Pereira J Watanabe S Opioid rotation in patients with cancer pain. A retrospective comparison of dose ratios between methadone, hydromorphone, and morphine. Cancer 1996;78:852–7.

Lawlor P Turner K Hanson J Bruera E . Dose ratio between morphine and methadone in patients with cancer pain: A retrospective study. Cancer 1998;82:1167–73.

Ripamonti C Groff L Brunelli C Switching from morphine to oral methadone in treating cancer pain: What is the equianalgesic dose ratio? J Clin Oncol 1998;16:3216–21.

Benitez-Rosario MA Ferla M Salinas-Martin A Martinez-Castillo LP Martin-Ortega JJ . Opioid switching from transdermal fentanyl to oral methadone in patients with cancer pain. Cancer 2004;101:2866–73.

Mercadante S Ferrera P Villari P Casuccio A . Rapid switching between transdermal fentanyl and methadone in cancer patients. J Clin Oncol 2005;23:5229–34.

Benitez-Rosario MA Salinas-Martin A Aguirre-Jaime A Perez-Mendez L Feria M . Morphine-methadone opioid rotation in cancer patients: Analysis of dose ratio predicting factors. J Pain Symptom Manage 2009;37:1061–8.

Mercadante S Arcuri E . Hyperalgesia and opioid switching. Am J Hosp Palliat Care 2005;22:291–4.

Mercadante S Casuccio A Fulfaro F Switching from morphine to methadone to improve analgesia and tolerability in cancer patients: A prospective studies. J Clin Oncol 2001;19:2898–904.

Bunten H Liang WJ Pounder DJ Seneviratne C Osselton D . OPRM1 and CYP2B6 gene variants as risk factors in methadone-related deaths. Clin Pharmacol Ther 2010;88:383–9.

Klepstad P Fladvad T Skorpen F Influence from genetic variability on opioid use for cancer pain: A European genetic association study of 2,294 cancer pain patients. Pain 2011;152:1139–45.