Susceptibility of Streptococcus mutans and Streptococcus sobrinus to antimicrobial agents after short‐term oral chlorhexidine treatments

European Journal of Oral Sciences - Tập 103 Số 1 - Trang 32-35 - 1995
H Järvinen1, Kaisu Pienihäkkinen2, Pentti Huovinen1, Jorma Tenovuo2
1Antimicrobial Research Laboratory, National Public Health Institute, Turku, Finland
2Department of Cariology, Institute of Dentistry, Turku University, Turku, Finland

Tóm tắt

Effects of three different types of short‐term applications (1–3 limes during 1 week) of chlorhexidine (1 or 40%) on the susceptibility of 863 clinical isolates of Streptococcus mutans and 53 isolates of Streptococcus sobrinus from 58 subjects were studied. Chlorhexidine‐resistant isolates were not found either before or after the treatment. The minimum inhibitory concentrations (MICs) to chlorhexidine of all isolates of S. mutans were ≤1 μg/ml, and of S. sobrinus≤2 μg/ ml. S. mutans and S. sobrinus were also susceptible to ampicillin, penicillin, cefuroxime, and tetracycline. In conclusion, different short‐term chlorhexidine regimens do not induce resistance in S. mutans or S. sobrinus and, furthermore, these species have so far retained their susceptibility to common antibiotics.

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Thông tin xuất bản

European Journal of Oral Sciences

Tập 103 Số 1

32-35

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