Surviving Intensive Care: a report from the 2002 Brussels Roundtable

Intensive Care Medicine - Tập 29 Số 3 - Trang 368-377 - 2003
Derek C. Angus1, Jean Carlet2
1Department of Health Policy and Management, Graduate School of Public Health, University of Pittsburgh, 3550 Terrace Street, Pittsburgh, PA, 15261, USA
2Anesthesiology and Emergency Department, Foundation Hôpital Saint Joseph, Paris, France

Tóm tắt

Từ khóa


Tài liệu tham khảo

Angus DC, Carlet J (eds) (2002) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York

Keenan SP, Dodek P (2002) Survival as an outcome for ICU patients. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York

Ely EW (2002) Understanding outcomes of critically ill older patients. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York

Herridge MS (2002) Morbidity and functional limitations in survivors of ARDS. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York

Randolph AG, Graham R (2002) Measuring the health status of pediatric ICU survivors. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York

Sukantarat KT, Brett S (2002) The neuropsychological consequences of intensive care. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York

Rowan K, Jenkinson C, Black N (2002) Health-related quality of life. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York

Levy MM (2002) The burden of caregiving on families of ICU survivors. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York

Kalassian KG, Angus DC (2002) Long-term economic consequences of surviving intensive care. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York

Quartin AA, Schein RM, Kett DH, Peduzzi PN, for the Department of Veterans Affairs Systemic Sepsis Cooperative Studies Group (1997) Magnitude and duration of the effect of sepsis on survival. JAMA 277:1058–1063

Keenan SP, Dodek P, Chan K, Hogg RS, Craib KJP, Anis AH, Spinelli JJ (2002) Intensive care unit admission has minimal impact on long-term mortality. Crit Care Med 30:501–507

Kaplan V, Clermont G, Griffin MF, Kasal J, Watson RS, Linde-Zwirble WT, Angus DC (2002) Pneumonia-still the old man's friend? Arch Intern Med (in press)

Angus DC, Musthafa AA, Clermont G, Griffin MF, Linde-Zwirble WT, Dremsizov TT, Pinsky MR (2001) Quality-adjusted survival in the first year after the acute respiratory distress syndrome. Am J Respir Crit Care Med 163:1389–1394

Davidson TA, Rubenfeld GD, Caldwell ES, Hudson LD, Steinberg KP (1999) The effect of acute respiratory distress syndrome on long-term survival. Am J Respir Crit Care Med 160:1838–1842

Perl TM, Dvorak L, Hwang T, Wenzel RP (1995) Long-term survival and function after suspected gram-negative sepsis. JAMA 274:338–345

Parno JR, Teres D, Lemeshow S, Brown RB (1982) Hospital charges and long-term survival of ICU versus non-ICU patients. Crit Care Med 10:569–574

Thibault GE, Mulley AG, Barnett GO, Goldstein RL, Reder VA, Sherman EL, Skinner ER (1980) Medical intensive care: indications, interventions, and outcomes. N Engl J Med 302:938–942

Bams JL, Miranda DR (1985) Outcome and costs of intensive care: a follow-up study on 238 ICU-patients. Intensive Care Med 11:234–241

Jacobs CJ, van der Vliet JA, van Roozendaal MT, van der Linden CJ (1988) Mortality and quality of life after intensive care for critical illness. Intensive Care Med 14:217–220

Mundt DJ, Gage RW, Lemeshow S, Pastides H, Teres D, Avrunin JS (1989) Intensive care unit patient follow-up. Mortality, functional status, and return to work at six months. Arch Intern Med 149:68–72

Ridley S, Jackson R, Findlay J, Wallace P (1990) Long term survival after intensive care. BMJ 301:1127–1130

Ridley S, Plenderleith L (1994) Survival after intensive care. Comparison with a matched normal population as an indicator of effectiveness. Anaesthesia 49:933–935

Niskanen M, Kari A, Halonen P (1996) Five-year survival after intensive care-comparison of 12:180 patients with the general population. Finnish ICU Study Group. Crit Care Med 24:1962–1967

Capuzzo M, Bianconi M, Contu P, Pavoni V, Gritti G (1996) Survival and quality of life after intensive care. Intensive Care Med 22:947–953

Short TG, Buckley TA, Rowbottom MY, Wong E, Oh TE (1999) Long-term outcome and functional health status following intensive care in Hong Kong. Crit Care Med 27:51–57

Eddleston JM, White P, Guthrie E (2000) Survival, morbidity, and quality of life after discharge from intensive care. Crit Care Med 28:2293–2299

Flaatten H, Kvale R (2001) Survival and quality of life 12 years after ICU. A comparison with the general Norwegian population. Intensive Care Med 27:1005–1011

Montuclard L, Garrouste-Orgeas M, Timsit JF, Misset B, De Jonghe B, Carlet J (2000) Outcome, functional autonomy, and quality of life of elderly patients with a long-term intensive care unit stay. Crit Care Med 28:3389–3395

Tsevat J, Cook EF, Green ML, Matchar DB, Dawson NV, Broste SK, Wu AW, Phillips RS, Oye RK, Goldman L (1995) Health values of the seriously ill. SUPPORT investigators. Ann Intern Med 122:514–520

McHugh LG, Milberg JA, Whitcomb ME, Schoene RB, Maunder RJ, Hudson LD (1994) Recovery of function in survivors of the acute respiratory distress syndrome. Am J Respir Crit Care Med 150:90–94

Weinert CR, Gross CR, Kangas JR, Bury CL, Marinelli WA (1997) Health-related quality of life after acute lung injury. Am J Respir Crit Care Med 156:1120–1128

Schelling G, Stoll C, Haller M, Briegel J, Manert W, Hummel T, Lenhart A, Heyduck M, Polasek J, Meier M, Preuss U, Bullinger M, Schuffel W, Peter K (1998) Health-related quality of life and posttraumatic stress disorder in survivors of the acute respiratory distress syndrome. Crit Care Med 26:651–659

Ely EW, Inouye SK, Bernard GR, Gordon S, Francis J, May L, Truman B, Speroff T, Gautam S, Margolin R, Hart RP, Dittus R (2001) Delirium in mechanically ventilated patients-Validity and reliability of the Confusion Assessment Method for the intensive care unit (CAM-ICU). JAMA 286:2703–2710

Hopkins RO, Weaver LK, Pope D, Orme JF, Bigler ED, Larson-Lohr V (1999) Neuropsychological sequelae and impaired health status in survivors of severe acute respiratory distress syndrome. Am J Respir Crit Care Med 160:50–56

Hopkins RO, Gale SD, Pope D, Weaver LK, Bigler ED (2000) Ventricular enlargement in patients with acute respiratory distress syndrome (abstract). J Int Neuropsychol Soc 6:229

Hopkins RO (2001) Brain imaging, neurocognitive sequelae and health related quality of life following acute respiratory distress syndrome. In: SG Pandalai (ed) Recent research developments in respiratory and critical care medicine. Research Signpost, Kerala, pp 209–222

Herridge MS (2002) Long-term outcomes after critical illness. Curr Opin Crit Care 8:331–336

Davidson TA, Caldwell ES, Curtis JR, Hudson LD, Steinberg KP (1999) Reduced quality of life in survivors of acute respiratory distress syndrome compared with critically ill control patients. JAMA 281:354–360

Woods NF, Haberman MR, Packard NJ (1993) Demands of illness and individual, dyadic, and family adaptation in chronic illness. West J Nurs Res 15:10–30

Donelan K, Falik M, DesRoches CM (2001) Caregiving: challenges and implications for women's health. Womens Health Issues 11:185–200

Angus DC (1997) Understanding the incidence and long-term outcome of ARDS. In: Gullo A (ed) Anaesthesia, pain, intensive care and emergency medicine: scientific report. Springer, Berlin Heidelberg New York, pp 289–298

Pronovost PJ, Jencks M, Dorman T, Garrett E, Rosenfeld BA, Breslow MJ, Lipsett PA, Bass EB (1999) Organizational characteristics of intensive care units related to outcomes of abdominal aortic surgery. JAMA 281:1310–1312

Brown JJ, Sullivan G (1989) Effect on ICU mortality of a full-time critical care specialist. Chest 96:127–129

Baldock G, Foley P, Brett S (2001) The impact of organisational change on outcome in an intensive care unit in the United Kingdom. Intensive Care Med 27:865–872

Kuo HS, Tang GJ, Chuang JH, Lee CH, Lui WY, Lee TY, P'eng FK (2000) Changing ICU mortality in a decade-effect of full-time intensivist. Crit Care Shock 3:57–61

Multz AS, Chalfin DB, Samson IM, Dantzker DR, Fein AM, Steinberg HN, Niederman MS, Scharf SM (1998) A "closed" medical intensive care unit (MICU) improves resource utilization when compared with an "open" MICU. Am J Respir Crit Care Med 157:1468–1473

Reynolds HN, Haupt MT, Thill-Baharozian MC, Carlson RW (1988) Impact of critical care physician staffing on patients with septic shock in a university hospital medical intensive care unit. JAMA 260:3446–3450

Al-Asadi L, Dellinger RP, Deutch J, Nathan SS (1996) Clinical impact of closed versus open provider care in a medical intensive care unit (abstract). Am J Respir Crit Care Med 153:A360

Carson SS, Stocking C, Podsadecki T, Christenson J, Pohlman A, MacRae S, Jordan J, Humphrey H, Siegler M, Hall J (1996) Effects of organizational change in the medical intensive care unit of a teaching hospital: a comparison of 'open' and 'closed' formats. JAMA 276:322–328

Ghorra S, Reinert SE, Cioffi W, Buczko G, Simms HH (1999) Analysis of the effect of conversion from open to closed surgical intensive care unit. Ann Surg 229:163–171

Li TC, Phillips MC, Shaw L, Cook EF, Natanson C, Goldman L (1984) On-site physician staffing in a community hospital intensive care unit. Impact on test and procedure use and on patient outcome. JAMA 252:2023–2027

Jacobs MC, Hussain E, Hanna A, Ruskin G, Weiss S, Skrzpiec W, Sison C, Cohn E (1998) Improving the outcome and efficiency of surgical intensive care: the impact of full time medical intensivists (abstract). Chest 114:276S-277S

Manthous CA, Amoateng-Adjepong Y, al-Kharrat T, Jacob B, Alnuaimat HM, Chatila W, Hall JB (1997) Effects of a medical intensivist on patient care in a community teaching hospital. Mayo Clin Proc 72:391–399

Marini CP, Nathan IM, Ritter G, Rivera L, Jurkiewicz A, Cohen JR (1995) The impact of full-time surgical intensivists on ICU utilization and mortality (abstract). Crit Care Med 23:A235

Pollack MM, Katz RW, Ruttimann UE, Getson PR (1988) Improving the outcome and efficiency of intensive care: the impact of an intensivist. Crit Care Med 16:11–17

Reich HS, Buhler L, David M, Whitmer G (1998) Saving lives in the community. Impact of intensive care leadership (abstract). Crit Care Med 25:A44

Tai DYH, Goh SK, Eng PCT, Wang YT (1998) Impact on quality of patient care and procedure use in the medical intensive care unit (MICU) following reorganisation. Ann Acad Med Singapore 27:309–313

Pollack MM, Cuerdon TT, Patel KM, Ruttimann UE, Getson PR, Levetown M (1994) Impact of quality-of-care factors on pediatric intensive care unit mortality. JAMA 272:941–946

DiCosmo BF (1999) Addition of an intensivist improves ICU outcomes in a non-teaching community hospital (abstract). Chest 116:238S

Dimick JB, Pronovost PJ, Heitmiller RF, Lipsett PA (2001) Intensive care unit physician staffing is associated with decreased length of stay, hospital cost, and complications after esophageal resection. Crit Care Med 29:753–758

Dimick JB, Pronovost PJ, Lipsett PA (2000) The effect of ICU physician staffing and hospital volume on outcomes after hepatic resection (abstract). Crit Care Med 28:A77

Rosenfeld BA, Dorman T, Breslow MJ, Pronovost P, Jenckes M, Zhang N, Anderson G, Rubin H (2000) Intensive care unit telemedicine: alternate paradigm for providing continuous intensivist care. Crit Care Med 28:3925–3931

Diringer MN, Edwards DF (2001) Admission to a neurologic/neurosurgical intensive care unit is associated with reduced mortality rate after intracerebral hemorrhage. Crit Care Med 29:635–640

Goh AYT, Lum LCS, Abdel-Latif MEA (2001) Impact of 24 hour critical care physician staffing on case-mix adjusted mortality in paediatric intensive care. Lancet 357:445–446

Blunt MC, Burchett KR (2000) Out-of-hours consultant cover and case-mix-adjusted mortality in intensive care. Lancet 356:735–736

Topeli A (2000) Effect of changing organization of intensive care unit from "open policy without critical care specialist" to "closed policy with critical care specialist" (abstract). Am J Respir Crit Care Med 161:A397

Hanson CW, Deutschman CS, Anderson HL, Reilly PM, Behringer EC, Schwab CW, Price J (1999) Effects of an organized critical care service on outcomes and resource utilization: a cohort study. Crit Care Med 27:270–274

Bernard GR, Vincent JL, Laterre PF, LaRosa SP, Dhainaut JF, Lopez-Rodriguez A, Steingrub JS, Garber GE, Helterbrand JD, Ely EW, Fisher CJ Jr, for the PROWESS Study Group (2001) Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 344:699–709

Kress JP, Pohlman AS, O'Connor MF, Hall JB (2000) Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation. N Engl J Med 342:1471–1477

Ely EW, Baker AM, Dunagan DP, Burke HL, Smith AC, Kelly PT, Johnson MM, Browder RW, Bowton DL, Haponik EF (1996) Effect on the duration of mechanical ventilation of identifying patients capable of breathing spontaneously. N Engl J Med 335:1864–1869

Hebert PC, Wells G, Blajchman MA, Marshall J, Martin C, Pagliarello G, Tweeddale M, Schweitzer I, Yetisir E (1999) A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group. N Engl J Med 340:409–417

Clermont G, Angus DC, Linde-Zwirble WT, Griffin MF, Fine MJ, Pinsky MR (2002) Does acute organ dysfunction predict patient-centered outcomes? Chest 121:1963–1971

Heyland DK, Guyatt G, Cook DJ, Meade M, Juniper E, Cronin L, Gafni A (1998) Frequency and methodologic rigor of quality-of-life assessments in the critical care literature. Crit Care Med 26:591–598

Black NA, Jenkinson C, Hayes JA, Young D, Vella K, Rowan KM, Daly K, Ridley S (2001) Review of outcome measures used in adult critical care. Crit Care Med 29:2119–2124

Rothenhausler HB, Ehrentraut S, Stoll C, Schelling G, Kapfhammer HP (2001) The relationship between cognitive performance and employment and health status in long-term survivors of the acute respiratory distress syndrome: results of an exploratory study. Gen Hosp Psychiatry 23:88–94

Marquis KA, Curtis JR, Caldwel ES, et al (2000) Neuropsychologic sequelae in survivors of ARDS compared with critically ill control patients (abstract). Am J Respir Crit Care Med 16:A383

Hopkins RO (2002) How should we assess neuropsychological sequelae of critical illness? In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York

van Hout B, Angus DC (2002) How should we measure the economic consequences of critical illness? In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York

Cohen J, Guyatt G, Bernard GR, Calandra T, Cook D, Elbourne D, Marshall J, Nunn A, Opal S, on behalf of a UK Medical Research Council International Working Party (2001) New strategies for clinical trials in patients with sepsis and septic shock. Crit Care Med 29:880–886

Curtis JR (2002) Measuring health status after critical illness: where are we and where do we go from here? In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York

Angus DC, Rubenfeld GD, Roberts MS, Curtis JR, Connors AFJ, Cook DJ, Lave JR, Pinsky MR (2002) Understanding costs and cost-effectiveness in critical care: report from the Second American Thoracic Society Workshop on Outcomes Research. Am J Respir Crit Care Med 165:540–550

Rubenfeld GD, Angus DC, Pinsky MR, Curtis JR, Connors AFJ, Bernard GR, and the members of the Outcomes Research Workshop (1999) Outcomes research in critical care: results of the American Thoracic Society Critical Care Assembly Workshop on Outcomes Research. Am J Respir Crit Care Med 160:358–367

Ware JE Jr, Sherbourne CD (1992) The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care 30:473–483

The EuroQol Group (1990) EuroQol—a new facility for the measurement of health-related quality of life. Health Policy 16:199–208

Gold MR, Russell LB, Seigel JE, Weinstein MC (1996) Cost-effectiveness in health and medicine. Oxford University Press, New York

Brazier J, Roberts J, Deverill M (2002) The estimation of a preference-based measure of health from the SF-36. J Health Econ 21:271–292

McMullin J, Cook DJ (2002) Changing ICU behavior to focus on long-term outcomes. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York

Young C, Millo JL, Salmon J (2002) Reduction in post-ICU, in-hospital mortality following the introduction of an ICU nursing outreach service (abstract). Critical Care 6 [Suppl 1]:S117

Pronovost P, Wu A, Holzmueller CG (2002) Defining success in ICU care. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York

Hartleib M, Sibbald WJ (2002) Re-organizing health care systems to optimize critical care outcomes. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York

Rubenfeld GD et al. (2003) Surrogate measures of patient-centered outcomes. In: Angus, Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39

Packer M (1992) Effect of oral milrinone on mortality in severe chronic heart-failure. Verh Dtsch Ges Herz Kreislaufforsch 24:276

Echt DS, Liebson PR, Mitchell LB, Peters RW, Obias-Manno D, Barker AH, Arensberg D, Baker A, Friedman L, Greene HL (1991) Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial. N Engl J Med 324:781–788

Takala J, Ruokonen E, Webster NR, Nielsen MS, Zandstra DF, Vundelinckx G, Hinds CJ (1999) Increased mortality associated with growth hormone treatment in critically ill adults. N Engl J Med 341:785–792

Garland JS, Alex CP, Pauly TH, Whitehead VL, Brand J, Winston JF, Samuels DP, McAuliffe TL (1999) A three-day course of dexamethasone therapy to prevent chronic lung disease in ventilated neonates: a randomized trial. Pediatrics 104:91–99

Taylor HG, Klein N, Hack M (2000) School-age consequences of birth weight less than 750 g: a review and update. Dev Neuropsychol 17:289–321

O'Shea TM, Kothadia JM, Klinepeter KL, Goldstein DJ, Jackson BG, Weaver RG, Dillard RG (1999) Randomized placebo-controlled trial of a 42-day tapering course of dexamethasone to reduce the duration of ventilator dependency in very low birth weight infants: outcome of study participants at 1-year adjusted age. Pediatrics 104:15–21