Tỷ lệ sống sót và các yếu tố tiên lượng ở bệnh nhân ung thư đại trực tràng bên phải và bên trái giai đoạn I–IV: một nghiên cứu hồi cứu tại một trung tâm chưa lựa chọn
Tóm tắt
Ung thư đại trực tràng đã thể hiện một sự thay đổi đáng kể trong vài thập kỷ qua với tỷ lệ ngày càng tăng của vị trí khối u bên phải so với bên trái. Trong nghiên cứu hiện tại, chúng tôi nhằm mục đích tiết lộ những khác biệt lâm sàng và bệnh lý giữa ung thư đại trực tràng bên phải (rCC) và bên trái (lCC) liên quan đến tỷ lệ tử vong và các yếu tố dự đoán kết quả.
Tổng cộng, 417 bệnh nhân mắc ung thư đại tràng giai đoạn I–IV đã được phân tích trong nghiên cứu hồi cứu đơn trung tâm này. Tỷ lệ sống sót được đánh giá bằng phương pháp Kaplan–Meier và phân tích đơn/multi biến được thực hiện bằng mô hình hồi quy nguy cơ tỷ lệ Cox.
Nghiên cứu của chúng tôi không cho thấy sự khác biệt có ý nghĩa thống kê về tỷ lệ sống sót tổng thể giữa rCC và lCC giai đoạn I–IV (
Khía cạnh bên không cho thấy ảnh hưởng đáng kể nào đến tiên lượng tổng thể của bệnh nhân ung thư đại tràng. Tuy nhiên, sự khác biệt giữa các nhóm và các yếu tố tiên đoán sống sót rõ ràng đã được xác định ở bệnh nhân rCC và lCC.
Từ khóa
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