Surgical Salvage of Recurrent Cancer of the Head and Neck

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Kim AJ, Suh JD, Sercarz JA, Abemayor E, Head C, Funk G, et al. Salvage surgery with free flap reconstruction: factors affecting outcome after treatment of recurrent head and neck squamous carcinoma. Laryngoscope. 2007;117(6):1019–23.

Zafereo ME, Beadle BM, Weber RS. Carcinoma of the Oropharynx. In: Mehanna HM, Ang KK, editors. Head and Neck Cancer Recurrence. Stuggart: Thieme; 2012. p. 145–62.

Zbären P, Nuyens M, Curschmann J, Stauffer E. Histologic characteristics and tumor spread of recurrent glottic carcinoma: analysis on whole-organ sections and comparison with tumor spread of primary glottic carcinomas. Head Neck. 2007;29(1):26–32.

Ho AS, Kraus DH, Ganly I, Lee NY, Shah JP, Morris LG. Decision making in the management of recurrent head and neck cancer. Head Neck. 2014;36(1):144–51.

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Sperry SM, Rassekh CH, Laccourreye O, Weinstein GS. Supracricoid partial laryngectomy for primary and recurrent laryngeal cancer. JAMA Otolaryngol Head Neck Surg. 2013;139(11):1226–35.

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Yu KH, Leung SF, Tung SY, Zee B, Chua DT, Sze WM, et al. Survival outcome of patients with nasopharyngeal carcinoma with first local failure: a study by the Hong Kong Nasopharyngeal Carcinoma Study Group. Head Neck. 2005;27(5):397–405.

Chua DT, Wu SX, Lee V, Tsang J. Comparison of single versus fractionated dose of stereotactic radiotherapy for salvaging local failures of nasopharyngeal carcinoma: a matched-cohort analysis. Head Neck Oncol. 2009;1:13.

Qiu S, Lin S, Tham IW, Pan J, Lu J, Lu JJ. Intensity-modulated radiation therapy in the salvage of locally recurrent nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys. 2012;83(2):676–83.

Wie WI, Kwong LWD. Carcinoma of the Nasopharynx. In: Mehanna HM, Ang KK, editors. Head and Neck Cancer Recurrence. Stuggart: Thieme; 2012. p. 175–90.

Yin Tsang RK, Ho WK, Wei WI. Combined transnasal endoscopic and transoral robotic resection of recurrent nasopharyngeal carcinoma. Head Neck. 2012;34(8):1190–3. This case report of combined transnasal endoscopic and transoral robotic resection of a recurrent nasopharyngeal carcinoma provides an example of surgical advances in minimally invasive resection of select small nasopharyngeal recurrences.

Wei WI, Chan JY, Ng RW, Ho WK. Surgical salvage of persistent or recurrent nasopharyngeal carcinoma with maxillary swing approach - Critical appraisal after 2 decades. Head Neck. 2011;33(7):969–75.

Chan JY, Wei WI. Recurrent nasopharyngeal carcinoma after salvage nasopharyngectomy. Arch Otolaryngol Head Neck Surg. 2012;138(6):572–6.

Chan YW, Chow VL, Wei WI. Quality of life of patients after salvage nasopharyngectomy for recurrent nasopharyngeal carcinoma. Cancer. 2012;118(15):3710–8.

Klug C, Berzaczy D, Voracek M, Enislidis G, Rath T, Millesi W, et al. Experience with microvascular free flaps in preoperatively irradiated tissue of the oral cavity and oropharynx in 303 patients. Oral Oncol. 2005;41(7):738–46.

Taki S, Homma A, Oridate N, Suzuki S, Suzuki F, Sakashita T, et al. Salvage surgery for local recurrence after chemoradiotherapy or radiotherapy in hypopharyngeal cancer patients. Eur Arch Otorhinolaryngol. 2010;267(11):1765–9.

Homer J, Slevin N, Priyamal S. Management of Recurrent Hypopharyngeal Cancer. In: Mehanna HM, Ang KK, editors. Head and Neck Cancer Recurrence. Stuggart: Thieme; 2012. p. 127–32.

Lewin JS, Barringer DA, May AH, Gillenwater AM, Arnold KA, Roberts DB, et al. Functional outcomes after laryngopharyngectomy with anterolateral thigh flap reconstruction. Head Neck. 2006;28(2):142–9.

Fakhry N, Chamorey E, Michel J, Collet C, Santini L, Poissonnet G, et al. Salvage circular laryngopharyngectomy and radial forearm free flap for recurrent hypopharyngeal cancer. Laryngoscope. 2013;123(4):910–5.

Kadota H, Fukushima J, Nakashima T, Kumamoto Y, Yoshida S, Yasumatsu R, et al. Comparison of salvage and planned pharyngolaryngectomy with jejunal transfer for hypopharyngeal carcinoma after chemoradiotherapy. Laryngoscope. 2010;120(6):1103–8.

Clark JR, de Almeida J, Gilbert R, Irish J, Brown D, Neligan P, et al. Primary and salvage (hypo)pharyngectomy: Analysis and outcome. Head Neck. 2006;28(8):671–7.

Dziegielewski PT, Ho ML, Rieger J, Singh P, Langille M, Harris JR, et al. Total glossectomy with laryngeal preservation and free flap reconstruction: objective functional outcomes and systematic review of the literature. Laryngoscope. 2013;123(1):140–5.

Weber RS, Berkey BA, Forastiere A, Cooper J, Maor M, Goepfert H, et al. Outcome of salvage total laryngectomy following organ preservation therapy: the Radiation Therapy Oncology Group trial 91-11. Arch Otolaryngol Head Neck Surg. 2003;129(1):44–9.

Li M, Lorenz RR, Khan MJ, Burkey BB, Adelstein DJ, Greskovich Jr JF, et al. Salvage laryngectomy in patients with recurrent laryngeal cancer in the setting of nonoperative treatment failure. Otolaryngol Head Neck Surg. 2013;149(2):245–51.

Patel UA, Keni SP. Pectoralis myofascial flap during salvage laryngectomy prevents pharyngocutaneous fistula. Otolaryngol Head Neck Surg. 2009;141(2):190–5.

Yu P, Hanasono MM, Skoracki RJ, Baumann DP, Lewin JS, Weber RS, et al. Pharyngoesophageal reconstruction with the anterolateral thigh flap after total laryngopharyngectomy. Cancer. 2010;116(7):1718–24.

Sinclair CF, Rosenthal EL, McColloch NL, Magnuson JS, Desmond RA, Peters GE, et al. Primary versus delayed tracheoesophageal puncture for laryngopharyngectomy with free flap reconstruction. Laryngoscope. 2011;121(7):1436–40.

Emerick KS, Tomycz L, Bradford CR, Lyden TH, Chepeha DB, Wolf GT, et al. Primary versus secondary tracheoesophageal puncture in salvage total laryngectomy following chemoradiation. Otolaryngol Head Neck Surg. 2009;140(3):386–90.

Holsinger FC, Funk E, Roberts DB, Diaz Jr EM. Conservation laryngeal surgery versus total laryngectomy for radiation failure in laryngeal cancer. Head Neck. 2006;28(9):779–84.

Ganly I, Patel SG, Matsuo J, Singh B, Kraus DH, Boyle JO, et al. Results of surgical salvage after failure of definitive radiation therapy for early-stage squamous cell carcinoma of the glottic larynx. Arch Otolaryngol Head Neck Surg. 2006;132(1):59–66.

Cohen MA, Nassif R, Goldstein DP, Gilbert R, Gullane P. Recurrent Laryngeal Cancer. In: Mehanna HM, Ang KK, editors. Head and Neck Cancer Recurrence. Stuggart: Thieme; 2012. p. 113–26.

Sperry SM, Rassekh CH, Laccourreye O, Weinstein GS. Supracricoid partial laryngectomy for primary and recurrent laryngeal cancer. JAMA Otolaryngol Head Neck Surg. 2013;139(11):1226–35. This article reports outcomes for 42 patients with laryngeal squamous cell carcinoma who were treated between 1992 and 2010 with supracricoid partial laryngectomy after previous radiation. Five-year local control with organ preservation was 89%, but 8 patients (19%) ultimately required total laryngectomy. It is important to note that even in a high-volume center, only approximately 2 patients per year were treated with this approach.

Gilbert RW, Goldstein DP, Guillemaud JP, Patel RS, Higgins KM, Enepekides DJ. Vertical partial laryngectomy with temporoparietal free flap reconstruction for recurrent laryngeal squamous cell carcinoma: technique and long-term outcomes. Arch Otolaryngol Head Neck Surg. 2012;138(5):484–91. This article reports technique and long-term outcomes for 40 patients treated with vertical partial laryngectomy with temporoparietal free flap reconstruction for recurrent laryngeal squamous cell carcinoma between 1995 and 2010. Five-year overall survival was 69%, and patients had only mild impairment on standardized speech, swallowing, and quality-of-life outcomes tests.

Agra IM, Ferlito A, Takes RP, Silver CE, Olsen KD, Stoeckli SJ, et al. Diagnosis and treatment of recurrent laryngeal cancer following initial nonsurgical therapy. Head Neck. 2012;34(5):727–35.