Superoxide dismutase multigene family: a comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression

Free Radical Biology and Medicine - Tập 33 Số 3 - Trang 337-349 - 2002
Igor N. Zelko1, Thomas J. Mariani2, Rodney J. Folz3
1Division of Pulmonary and Critical Care, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.
2Pulmonary Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
3Division of Pulmonary and Critical Care, Departments of Medicine and Cell Biology, Duke University Medical Center, Durham, NC, USA

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Chang, 1988, Molecular immunocytochemistry of the CuZn superoxide dismutase in rat hepatocytes, J. Cell Biol., 107, 2169, 10.1083/jcb.107.6.2169

Keller, 1991, Cu,Zn superoxide dismutase is a peroxisomal enzyme in human fibroblasts and hepatoma cells, Proc. Natl. Acad. Sci. USA, 88, 7381, 10.1073/pnas.88.16.7381

Crapo, 1992, Copper, zinc superoxide dismutase is primarily a cytosolic protein in human cells, Proc. Natl. Acad. Sci. USA, 89, 10405, 10.1073/pnas.89.21.10405

Liou, 1993, Distribution of CuZn superoxide dismutase in rat liver, Free Radic. Biol. Med., 14, 201, 10.1016/0891-5849(93)90011-I

Marklund, 1982, Human copper-containing superoxide dismutase of high molecular weight, Proc. Natl. Acad. Sci. USA, 79, 7634, 10.1073/pnas.79.24.7634

Marklund, 1982, Superoxide dismutase in extracellular fluids, Clin. Chim. Acta, 126, 41, 10.1016/0009-8981(82)90360-6

Marklund, 1986, Superoxide dismutase isoenzymes of the synovial fluid in rheumatoid arthritis and in reactive arthritides, Ann. Rheum. Dis., 45, 847, 10.1136/ard.45.10.847

Weisiger, 1973, Mitochondrial superoxide dismutase, J. Biol. Chem., 248, 4793, 10.1016/S0021-9258(19)43735-6

Barra, 1984, The primary structure of human liver manganese superoxide dismutase, J. Biol. Chem., 259, 12595, 10.1016/S0021-9258(18)90788-X

St. Clair, 1994, Expression of manganese superoxide dismutase promotes cellular differentiation, Free Radic. Biol. Med., 16, 275, 10.1016/0891-5849(94)90153-8

Wispe, 1992, Human Mn-superoxide dismutase in pulmonary epithelial cells of transgenic mice confers protection from oxygen injury, J. Biol. Chem, 267, 23937, 10.1016/S0021-9258(18)35927-1

Fridovich, 1995, Superoxide radical and superoxide dismutases, Annu. Rev. Biochem., 64, 97, 10.1146/annurev.bi.64.070195.000525

Bannister, 1987, Aspects of the structure, function, and applications of superoxide dismutase, CRC Crit. Rev. Biochem., 22, 111, 10.3109/10409238709083738

McCord, 1988, Superoxide dismutase, Free Radic. Biol. Med., 5, 363, 10.1016/0891-5849(88)90109-8

Oberley, 1979, Role of superoxide dismutase in cancer, Cancer Res., 39, 1141

Fridovich, 1997, Superoxide anion radical (O2·−), superoxide dismutases, and related matters, J. Biol. Chem., 272, 18515, 10.1074/jbc.272.30.18515

Fridovich, 1989, Superoxide dismutases. An adaptation to a paramagnetic gas, J. Biol. Chem., 264, 7761, 10.1016/S0021-9258(18)83102-7

Kim, 1993, Isolation and analysis of the rat genomic sequence encoding Cu/Zn superoxide dismutase, Gene, 133, 267, 10.1016/0378-1119(93)90650-R

Hsu, 1992, Rat copper/zinc superoxide dismutase gene, Biochem. Biophys. Res. Commun., 186, 936, 10.1016/0006-291X(92)90836-A

Benedetto, 1991, Isolation and analysis of the mouse genomic sequence encoding Cu-Zn superoxide dismutase, Gene, 99, 191, 10.1016/0378-1119(91)90126-V

Levanon, 1985, Architecture and anatomy of the chromosomal locus in human chromosome 21 encoding the Cu/Zn superoxide dismutase, EMBO J., 4, 77, 10.1002/j.1460-2075.1985.tb02320.x

Kim, 1994, Study of 5′-flanking region of human Cu/Zn superoxide dismutase, Biochem. Biophys. Res. Commun., 201, 1526, 10.1006/bbrc.1994.1877

Minc, 1999, The human copper-zinc superoxide dismutase gene (SOD1) proximal promoter is regulated by Sp1, Egr-1, and WT1 via non-canonical binding sites, J. Biol. Chem., 274, 503, 10.1074/jbc.274.1.503

Church, 1992, Sublocalization of the gene encoding manganese superoxide dismutase (MnSOD/SOD2) to 6q25 by fluorescence in situ hybridization and somatic cell hybrid mapping, Genomics, 14, 823, 10.1016/S0888-7543(05)80202-2

Wan, 1994, Molecular structure and organization of the human manganese superoxide dismutase gene, DNA Cell Biol., 13, 1127, 10.1089/dna.1994.13.1127

Ho, 1991, Molecular structure of a functional gene for manganese-containing superoxide dismutase, Am. J. Respir. Cell Mol. Biol., 4, 278, 10.1165/ajrcmb/4.3.278

DiSilvestre, 1995, Structure and DNA sequence of the mouse MnSOD gene, Mamm. Genome, 6, 281, 10.1007/BF00352417

Jones, 1995, Cloning and characterization of the murine manganous superoxide dismutase-encoding gene, Gene, 153, 155, 10.1016/0378-1119(94)00666-G

Meyrick, 1994, Identification and functional characterization of the bovine manganous superoxide dismutase promoter, Am. J. Respir. Cell Mol. Biol., 10, 113, 10.1165/ajrcmb.10.1.8292376

Jones, 1988, Trans-acting protein factors and the regulation of eukaryotic transcription, Genes Dev., 2, 267, 10.1101/gad.2.3.267

Dynan, 1986, Promoters for housekeeping genes, TIG, 2, 196, 10.1016/0168-9525(86)90226-X

Folz, 1994, Extracellular superoxide dismutase (SOD3), Genomics, 22, 162, 10.1006/geno.1994.1357

Carlsson, 1995, Mice lacking extracellular superoxide dismutase are more sensitive to hyperoxia, Proc. Natl. Acad. Sci. USA, 92, 6264, 10.1073/pnas.92.14.6264

Hjalmarsson, 1987, Isolation and sequence of complementary DNA encoding human extracellular superoxide dismutase, Proc. Natl. Acad. Sci. USA, 84, 6340, 10.1073/pnas.84.18.6340

Perry, 1993, Isolation and characterization of a rat cDNA clone encoding a secreted superoxide dismutase reveals the epididymis to be a major site of its expression, Biochem. J., 293, 21, 10.1042/bj2930021

Willems, 1993, Purification and sequence of rat extracellular superoxide dismutase B secreted by C6 glioma, J. Biol. Chem., 268, 24614, 10.1016/S0021-9258(19)74510-4

Folz, 1997, Mouse extracellular superoxide dismutase, Am. J. Respir. Cell Mol. Biol., 17, 393, 10.1165/ajrcmb.17.4.2826

Laukkanen, 1995

Schmutz, 1996, Physical mapping of SOD1 to bovine chromosome 1, Cytogenet. Cell Genet., 72, 37, 10.1159/000134156

Francke, 1979, Assignment of the gene for cytoplasmic superoxide dismutase (SOD-1) to a region of chromosome 16 and of Hprt to a region of the X chromosome in the mouse, Proc. Natl. Acad. Sci. USA, 76, 5230, 10.1073/pnas.76.10.5230

Avraham, 1988, Down’s syndrome, Cell, 54, 823, 10.1016/S0092-8674(88)91153-1

Groner, 1994, Cell damage by excess CuZnSOD and Down’s syndrome, Biomed. Pharmacother., 48, 231, 10.1016/0753-3322(94)90138-4

De La Torre, 1996, Overexpression of copper-zinc superoxide dismutase in trisomy 21, Experientia, 52, 871, 10.1007/BF01938872

Rosen, 1993, Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis, Nature, 362, 59, 10.1038/362059a0

Gurney, 1994, Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation, Science, 264, 1772, 10.1126/science.8209258

Reaume, 1996, Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury, Nat. Genet., 13, 43, 10.1038/ng0596-43

Ho, 1998, Reduced fertility in female mice lacking copper-zinc superoxide dismutase, J. Biol. Chem., 273, 7765, 10.1074/jbc.273.13.7765

Wiedau-Pazos, 1996, Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis, Science, 271, 515, 10.1126/science.271.5248.515

Estevez, 1999, Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase, Science, 286, 2498, 10.1126/science.286.5449.2498

Bruijn, 1998, Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1, Science, 281, 1851, 10.1126/science.281.5384.1851

Chou, 1996, Role of SOD-1 and nitric oxide/cyclic GMP cascade on neurofilament aggregation in ALS/MND, J. Neurol. Sci., 139, 16, 10.1016/0022-510X(96)00090-1

Creagan, 1973, Chromosome assignments of genes in man using mouse-human somatic cell hybrids, Humangenetik, 20, 203, 10.1007/BF00385731

Lebovitz, 1996, Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice, Proc. Natl. Acad. Sci. USA, 93, 9782, 10.1073/pnas.93.18.9782

Rosenblum, 1996, On signal sequence polymorphisms and diseases of distribution, Proc. Natl. Acad. Sci. USA, 93, 4471, 10.1073/pnas.93.9.4471

Van Landeghem, 1999, Manganese-containing superoxide dismutase signal sequence polymorphism associated with sporadic motor neuron disease, Eur. J. Neurol., 6, 639, 10.1046/j.1468-1331.1999.660639.x

Hiroi, 1999, Polymorphisms in the SOD2 and HLA-DRB1 genes are associated with nonfamilial idiopathic dilated cardiomyopathy in Japanese, Biochem. Biophys. Res. Commun., 261, 332, 10.1006/bbrc.1999.1036

Farin, 2001, Genetic polymorphisms of superoxide dismutase in Parkinson’s disease, Mov. Disord., 16, 705, 10.1002/mds.1153

Parboosingh, 1995, Absence of mutations in the Mn superoxide dismutase or catalase genes in familial amyotrophic lateral sclerosis, Neuromuscul. Disord., 5, 7, 10.1016/0960-8966(94)E0022-Z

Tomkins, 2001, Mutation screening of manganese superoxide dismutase in amyotrophic lateral sclerosis, Neuroreport, 12, 2319, 10.1097/00001756-200108080-00008

Mitrunen, 2001, Association between manganese superoxide dismutase (MnSOD) gene polymorphism and breast cancer risk, Carcinogenesis, 22, 827, 10.1093/carcin/22.5.827

Zhang, 1999, Comparison of effects of two polymorphic variants of manganese superoxide dismutase on human breast MCF-7 cancer cell phenotype, Cancer Res., 59, 6276

Tomblyn, 1998, Distribution of MnSOD polymorphisms in sporadic ALS patients, J. Mol. Neurosci., 10, 65, 10.1007/BF02737086

Xu, 1999, Mutations in the promoter reveal a cause for the reduced expression of the human manganese superoxide dismutase gene in cancer cells, Oncogene, 18, 93, 10.1038/sj.onc.1202265

Hendrickson, 1990, Regional localization of human extracellular superoxide dismutase gene to 4pter-q21, Genomics, 8, 736, 10.1016/0888-7543(90)90264-U

Suh, 1997, Sequence analysis, tissue expression and chromosomal localization of a mouse secreted superoxide dismutase gene, Mol. Cells, 7, 204, 10.1016/S1016-8478(23)13281-X

Folz, 1994, Identification of a homozygous missense mutation (Arg to Gly) in the critical binding region of the human EC-SOD gene (SOD3) and its association with dramatic increased serum levels, Hum. Mol. Genet., 3, 2251, 10.1093/hmg/3.12.2251

Yamada, 1995, Molecular analysis of extracellular-superoxide dismutase gene associated with high level in serum, Jpn. J. Hum. Genet., 40, 177, 10.1007/BF01883574

Sandstrom, 1994, 10-Fold increase in human plasma extracellular superoxide dismutase content caused by a mutation in heparin-binding domain, J. Biol. Chem., 269, 19163, 10.1016/S0021-9258(17)32289-5

Marklund, 1997, Two variants of extracellular-superoxide dismutase, J. Intern. Med., 242, 5, 10.1046/j.1365-2796.1997.00160.x

Adachi, 1998, Association of extracellular-superoxide dismutase phenotype with the endothelial constitutive nitric oxide synthase polymorphism, FEBS Lett., 433, 166, 10.1016/S0014-5793(98)00903-X

Yamada, 1997, Polymorphism of extracellular superoxide dismutase (EC-SOD) gene, Jpn. J. Hum. Genet., 42, 353, 10.1007/BF02766958

Sheng, 1999, Extracellular superoxide dismutase deficiency worsens outcome from focal cerebral ischemia in the mouse, Neurosci. Lett., 267, 13, 10.1016/S0304-3940(99)00316-X

Levin, 1998, Molecular manipulations of extracellular superoxide dismutase, Behav. Genet., 28, 381, 10.1023/A:1021673703129

Bordo, 1994, Conserved patterns in the Cu,Zn superoxide dismutase family, J. Mol. Biol., 238, 366, 10.1006/jmbi.1994.1298

Getzoff, 1989, Evolution of CuZn superoxide dismutase and the Greek key beta-barrel structural motif, Proteins, 5, 322, 10.1002/prot.340050408

Smith, 1992, A comparison of evolutionary rates of the two major kinds of superoxide dismutase, J. Mol. Evol., 34, 175, 10.1007/BF00182394

Rodriguez-Trelles, 2001, Erratic overdispersion of three molecular clocks, Proc. Natl. Acad. Sci. USA, 98, 11405, 10.1073/pnas.201392198

Hass, 1988, Regulation of the synthesis of superoxide dismutases in rat lungs during oxidant and hyperthermic stresses, J. Biol. Chem., 263, 776, 10.1016/S0021-9258(19)35421-3

Yoo, 1999, The activation of the rat copper/zinc superoxide dismutase gene by hydrogen peroxide through the hydrogen peroxide-responsive element and by paraquat and heat shock through the same heat shock element, J. Biol. Chem., 274, 23887, 10.1074/jbc.274.34.23887

Inoue, 1996, Shear stress modulates expression of Cu/Zn superoxide dismutase in human aortic endothelial cells, Circ. Res., 79, 32, 10.1161/01.RES.79.1.32

Dimmeler, 1999, Upregulation of superoxide dismutase and nitric oxide synthase mediates the apoptosis-suppressive effects of shear stress on endothelial cells, Arterioscler. Thromb. Vasc. Biol., 19, 656, 10.1161/01.ATV.19.3.656

Isoherranen, 1997, Regulation of copper/zinc and manganese superoxide dismutase by UVB irradiation, oxidative stress and cytokines, J. Photochem. Photobiol. B, 40, 288, 10.1016/S1011-1344(97)00071-7

Leccia, 2001, Solar simulated irradiation modulates gene expression and activity of antioxidant enzymes in cultured human dermal fibroblasts, Exp. Dermatol., 10, 272, 10.1034/j.1600-0625.2001.100407.x

Yamaoka, 1994, Induction of two species of superoxide dismutase in some organs of rats by low dose X-irradiation, Physiol. Chem. Phys. Med. NMR, 26, 205

Yoo, 1999, Heavy metal-mediated activation of the rat Cu/Zn superoxide dismutase gene via a metal-responsive element, Mol. Gen. Genet., 262, 310, 10.1007/s004380051088

Rahman, 1991, Rat lung antioxidant enzyme induction by ozone, Am. J. Physiol., 260, L412

Frank, 2000, Identification of copper/zinc superoxide dismutase as a nitric oxide-regulated gene in human (HaCaT) keratinocytes, Biochem. J., 346, 719, 10.1042/bj3460719

Yoo, 1999, Induction of the rat Cu/Zn superoxide dismutase gene through the peroxisome proliferator-responsive element by arachidonic acid, Gene, 234, 87, 10.1016/S0378-1119(99)00176-6

Yoo, 1999, Xenobiotic-responsive element for the transcriptional activation of the rat Cu/Zn superoxide dismutase gene, Biochem. Biophys. Res. Commun., 256, 133, 10.1006/bbrc.1999.0299

Cho, 2001, Transcriptional activation of the human Cu/Zn superoxide dismutase gene by 2,3,7,8-tetrachlorodibenzo-p-dioxin through the xenobiotic-responsive element, Mol. Genet. Genomics, 266, 133, 10.1007/s004380100536

Ueda, 2002, Diverse roles of the nuclear orphan receptor CAR in regulating hepatic genes in response to phenobarbital, Mol. Pharmacol., 61, 1, 10.1124/mol.61.1.1

Seo, 1997, C/EBP alpha and C/EBPbeta play similar roles in the transcription of the human Cu/Zn SOD gene, Gene, 203, 11, 10.1016/S0378-1119(97)00484-8

Seo, 1996, Sp1 and C/EBP-related factor regulate the transcription of human Cu/Zn SOD gene, Gene, 178, 177, 10.1016/0378-1119(96)00383-6

Kim, 1997, C/EBP alpha is a major activator for the transcription of rat Cu/Zn superoxide dismutase gene in liver cell, FEBS Lett., 401, 267, 10.1016/S0014-5793(96)01487-1

Kim, 1996, Transcriptional activation of the Cu,Zn-superoxide dismutase gene through the AP2 site by ginsenoside Rb2 extracted from a medicinal plant, Panax ginseng, J. Biol. Chem., 271, 24539, 10.1074/jbc.271.40.24539

Jackson, 1996, Effects of hypoxia on expression of superoxide dismutases in cultured ATII cells and lung fibroblasts, Am. J. Physiol., 271, L955

Cho, 1997, The transcriptional repression of the human Cu/Zn superoxide dismutase(SOD1) gene by the anticancer drug, mitomycin C(MMC), Biochem. Mol. Biol. Int., 42, 949

Kuo, 1999, In vivo architecture of the manganese superoxide dismutase promoter, J. Biol. Chem., 274, 3345, 10.1074/jbc.274.6.3345

Zhang, 1996, Characterization of the 5′ flanking region of the human MnSOD gene, Biochem. Biophys. Res. Commun., 220, 171, 10.1006/bbrc.1996.0376

Yeh, 1998, Transcriptional regulation of the 5′ proximal promoter of the human manganese superoxide dismutase gene, DNA Cell Biol., 17, 921, 10.1089/dna.1998.17.921

Zhu, 2001, A family of AP-2 proteins down-regulate manganese superoxide dismutase expression, J. Biol. Chem., 276, 14407, 10.1074/jbc.M009708200

Masuda, 1988, Induction of mitochondrial manganese superoxide dismutase by interleukin 1, FASEB J., 2, 3087, 10.1096/fasebj.2.15.3263930

Visner, 1992, Regulation of manganese superoxide dismutase, Biochem. Biophys. Res. Commun., 188, 453, 10.1016/0006-291X(92)92406-N

Dougall, 1991, Manganese superoxide dismutase, Endocrinology, 129, 2376, 10.1210/endo-129-5-2376

Wong, 1988, Induction of mangenese superoxide dismutase by tumor necrosis factor, Science, 242, 941, 10.1126/science.3263703

Visner, 1990, Regulation of manganese superoxide dismutase by lipopolysaccharide, interleukin-1, and tumor necrosis factor, J. Biol. Chem., 265, 2856, 10.1016/S0021-9258(19)39880-1

Harris, 1991, Manganese superoxide dismutase is induced by IFN-gamma in multiple cell types. Synergistic induction by IFN-gamma and tumor necrosis factor or IL-1, J. Immunol., 147, 149, 10.4049/jimmunol.147.1.149

Jones, 1997, Tumor necrosis factor alpha and interleukin-1beta regulate the murine manganese superoxide dismutase gene through a complex intronic enhancer involving C/EBP-beta and NF-kappaB, Mol. Cell. Biol., 17, 6970, 10.1128/MCB.17.12.6970

Rogers, 2000, Cytokine-inducible enhancer with promoter activity in both the rat and human manganese-superoxide dismutase genes, Biochem. J., 347, 233, 10.1042/bj3470233

Kim, 1999, Transcriptional activation of the human manganese superoxide dismutase gene mediated by tetradecanoylphorbol acetate, J. Biol. Chem., 274, 37455, 10.1074/jbc.274.52.37455

Das, 1998, Protein kinase Cdelta-dependent induction of manganese superoxide dismutase gene expression by microtubule-active anticancer drugs, J. Biol. Chem., 273, 34639, 10.1074/jbc.273.51.34639

Thongphasuk, 1999, Induction of superoxide dismutase and cytotoxicity by manganese in human breast cancer cells, Arch. Biochem. Biophys., 365, 317, 10.1006/abbi.1999.1179

Maehara, 2001, Early growth-responsive-1-dependent manganese superoxide dismutase gene transcription mediated by platelet-derived growth factor, FASEB J., 15, 2025, 10.1096/fj.00-0909fje

Huang, 1997, Transcriptional inhibition of manganese superoxide dismutase (SOD2) gene expression by DNA methylation of the 5′ CpG island, Free Radic. Biol. Med., 23, 314, 10.1016/S0891-5849(97)00095-6

Huang, 1999, Decreased expression of manganese superoxide dismutase in transformed cells is associated with increased cytosine methylation of the SOD2 gene, DNA Cell Biol., 18, 643, 10.1089/104454999315051

Chung, 1998, The 3′ untranslated region of manganese superoxide dismutase RNA contains a translational enhancer element, Biochemistry, 37, 16298, 10.1021/bi980935g

Knirsch, 2000, A region in the 3′ UTR of MnSOD RNA enhances translation of a heterologous RNA, Biochem. Biophys. Res. Commun., 272, 164, 10.1006/bbrc.2000.2754

Knirsch, 2001, Tyrosine phosphorylation regulates manganese superoxide dismutase (MnSOD) RNA-binding protein activity and MnSOD protein expression, Biochemistry, 40, 7890, 10.1021/bi010197n

Stralin, 1995, The interstitium of the human arterial wall contains very large amounts of extracellular superoxide dismutase, Arterioscler. Thromb. Vasc. Biol., 15, 2032, 10.1161/01.ATV.15.11.2032

Loenders, 1998, Localization of extracellular superoxide dismutase in rat lung, Free Radic. Biol. Med., 24, 1097, 10.1016/S0891-5849(97)00434-6

Marklund, 1990, Expression of extracellular superoxide dismutase by human cell lines, Biochem. J., 266, 213, 10.1042/bj2660213

Marklund, 1992, Regulation by cytokines of extracellular superoxide dismutase and other superoxide dismutase isoenzymes in fibroblasts, J. Biol. Chem., 267, 6696, 10.1016/S0021-9258(19)50482-3

Mruk, 1998, Rat testicular extracellular superoxide dismutase, Biol. Reprod., 59, 298, 10.1095/biolreprod59.2.298

Brady, 1997, Extracellular superoxide dismutase is upregulated with inducible nitric oxide synthase after NF-kappa B activation, Am. J. Physiol., 273, L1002

Stralin, 2001, Vasoactive factors and growth factors alter vascular smooth muscle cell EC-SOD expression, Am. J. Physiol. Heart Circ. Physiol., 281, H1621, 10.1152/ajpheart.2001.281.4.H1621

Fukai, 2000, Regulation of the vascular extracellular superoxide dismutase by nitric oxide and exercise training, J. Clin. Invest., 105, 1631, 10.1172/JCI9551

Fukai, 1999, Modulation of extracellular superoxide dismutase expression by angiotensin II and hypertension, Circ. Res., 85, 23, 10.1161/01.RES.85.1.23

Nicolai, 1996, Cyclic AMP-induced differentiation increases the synthesis of extracellular superoxide dismutase in rat C6 glioma, Free Radic. Biol. Med., 21, 481, 10.1016/0891-5849(96)00122-0

Sugatani, 2001, The phenobarbital response enhancer module in the human bilirubin UDP-glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR, Hepatology, 33, 1232, 10.1053/jhep.2001.24172

Walther, 1991, Ontogeny of antioxidant enzymes in the fetal lamb lung, Exp. Lung Res., 17, 39, 10.3109/01902149109063280

Frank, 1984, Preparation for birth into an O2-rich environment, Pediatr. Res., 18, 240, 10.1203/00006450-198403000-00004

Yuan, 1996, Differential patterns of antioxidant enzyme mRNA expression in guinea pig lung and liver during development, Biochim. Biophys. Acta, 1305, 163, 10.1016/0167-4781(95)00214-6

Hass, 1987, Developmental regulation of rat lung Cu, Zn-superoxide dismutase, Biochem. J., 246, 697, 10.1042/bj2460697

Clerch, 1992, Rat lung antioxidant enzymes, Am. J. Physiol., 263, L466

Hayashibe, 1990, Prenatal development of antioxidant enzymes in rat lung, kidney, and heart, Pediatr. Res., 27, 472, 10.1203/00006450-199005000-00011

Schisler, 1985, Tissue-specific developmental regulation of superoxide dismutase (SOD-1 and SOD-2) activities in genetic strains of mice, Biochem. Genet., 23, 291, 10.1007/BF00504326

de Haan, 1994, Expression of copper/zinc superoxide dismutase and glutathione peroxidase in organs of developing mouse embryos, fetuses, and neonates, Pediatr. Res., 35, 188, 10.1203/00006450-199402000-00013

Strange, 1988, Studies on the expression of Cu, Zn superoxide dismutase in human tissues during development, Biochim. Biophys. Acta, 964, 260, 10.1016/0304-4165(88)90174-2

McElroy, 1992, Catalase, superoxide dismutase and glutathione peroxidase activities of lung and liver during human development, Biochim. Biophys. Acta, 1117, 153, 10.1016/0304-4165(92)90073-4

Autor, 1976, Developmental characteristics of pulmonary superoxide dismutase, Pediatr. Res., 10, 154, 10.1203/00006450-197603000-00002

Asikainen, 1998, Expression and developmental profile of antioxidant enzymes in human lung and liver, Am. J. Respir. Cell. Mol. Biol., 19, 942, 10.1165/ajrcmb.19.6.3248

Carbone, 1994, Expression of manganese superoxide dismutase in ovine kidney cortex during development, Pediatr. Res., 35, 41, 10.1203/00006450-199401000-00010

Vlessis, 1989, Perinatal development of heart, kidney, and liver mitochondrial antioxidant defense, Pediatr. Res., 26, 220, 10.1203/00006450-198909000-00013

Nozik-Grayck, 2000, Secretion of extracellular superoxide dismutase in neonatal lungs, Am. J. Physiol. Lung Cell. Mol. Physiol., 279, L977, 10.1152/ajplung.2000.279.5.L977

Adachi, 2000, Age-related change of plasma extracellular-superoxide dismutase, Clin. Chim. Acta, 290, 169, 10.1016/S0009-8981(99)00187-4

White, 1994, Superoxide and peroxynitrite in atherosclerosis, Proc. Natl. Acad. Sci. USA, 91, 1044, 10.1073/pnas.91.3.1044

Stralin, 2000, Multiple cytokines regulate the expression of extracellular superoxide dismutase in human vascular smooth muscle cells, Atherosclerosis, 151, 433, 10.1016/S0021-9150(99)00427-X

Tannahill, 1997, Regulation of superoxide dismutase in primary cultures of rat colonic smooth muscle cells, Am. J. Physiol., 272, G1230

Warner, 1991, Tumor necrosis factor-alpha increases Mn-SOD expression, Am. J. Physiol., 260, L296

White, 1994, Induction of pulmonary Mn superoxide dismutase mRNA by interleukin-1, Am. J. Physiol., 266, L664

Kifle, 1996, Regulation of the manganese superoxide dismutase and inducible nitric oxide synthase gene in rat neuronal and glial cells, J. Neurochem., 66, 2128, 10.1046/j.1471-4159.1996.66052128.x

Habelhah, 1998, [Induction of manganese superoxide dismutase by an immunopotentiator as a mechanism of inhibiting of malignant progression of murine tumor cells], Hokkaido Igaku Zasshi, 73, 519

Nishiguchi, 1994, Effect of epidermal growth factor on Cu, Zn-superoxide dismutase expression in cultured fibroblasts from rat skin, Pharm. Res., 11, 1244, 10.1023/A:1018978024740

Sano, 1996, Nitric oxide releasing reagent, S-nitroso-N-acetylpenicillamine, enhances the expression of manganese superoxide dismutase mRNA in rat vascular smooth muscle cells, J. Cell Biochem., 62, 50, 10.1002/(SICI)1097-4644(199607)62:1<50::AID-JCB6>3.0.CO;2-0

Pang, 2001, Analysis of genes differentially expressed in astrocytes stimulated with lipopolysaccharide using cDNA arrays, Brain Res., 914, 15, 10.1016/S0006-8993(01)02766-4

Fujii, 1991, Phorbol ester induces manganese-superoxide dismutase in tumor necrosis factor-resistant cells, J. Biol. Chem., 266, 23142, 10.1016/S0021-9258(18)54474-4

Mariani, 2002, Gene expression profiling of lung development, Am. J. Respir. Cell Mol. Biol., 26, 541, 10.1165/ajrcmb.26.5.2001-00080c