Sunitinib specifically augments glucose-induced insulin secretion
Tài liệu tham khảo
Carlisle, 2016, Benefit, risk, and outcomes in drug development: a systematic review of sunitinib, J. Natl. Cancer Inst., 108, 10.1093/jnci/djv292
Faivre, 2007, Molecular basis for sunitinib efficacy and future clinical development, Nat. Rev. Drug Discov., 6, 734, 10.1038/nrd2380
Templeton, 2008, Remission of diabetes while on sunitinib treatment for renal cell carcinoma, Ann. Oncol., 19, 824, 10.1093/annonc/mdn047
Billemont, 2008, Blood glucose levels in patients with metastatic renal cell carcinoma treated with sunitinib, Br. J. Cancer, 99, 1380, 10.1038/sj.bjc.6604709
Huda, 2014, Tyrosine kinase inhibitor sunitinib allows insulin independence in long-standing type 1 diabetes, Diabetes Care, 37, e87, 10.2337/dc13-2132
Agostino, 2011, Effect of the tyrosine kinase inhibitors (sunitinib, sorafenib, dasatinib, and imatinib) on blood glucose levels in diabetic and nondiabetic patients in general clinical practice, J. Oncol. Pharm. Pract., 17, 197, 10.1177/1078155210378913
Louvet, 2008, Tyrosine kinase inhibitors reverse type 1 diabetes in nonobese diabetic mice, Proc. Natl. Acad. Sci. U. S. A., 105, 18895, 10.1073/pnas.0810246105
Tyrrell, 2014, Sunitinib and improved diabetes control, BMJ Case Rep., 2014, 10.1136/bcr-2014-207521
Leroith, 2008, Mechanisms of disease: using genetically altered mice to study concepts of type 2 diabetes, Nat. Clin. Pract. Endocrinol. Metab., 4, 164, 10.1038/ncpendmet0729
Jabs, 2008, Reduced insulin secretion and content in VEGF-a deficient mouse pancreatic islets, Exp. Clin. Endocrinol. Diabetes, 116, S46, 10.1055/s-2008-1081486
Welsh, 1990, Coexpression of the platelet-derived growth factor (PDGF) B chain and the PDGF beta receptor in isolated pancreatic islet cells stimulates DNA synthesis, Proc. Natl. Acad. Sci. U. S. A., 87, 5807, 10.1073/pnas.87.15.5807
Lammert, 2003, Role of VEGF-A in vascularization of pancreatic islets, Curr. Biol., 13, 1070, 10.1016/S0960-9822(03)00378-6
Brissova, 2006, Pancreatic islet production of vascular endothelial growth factor–a is essential for islet vascularization, revascularization, and function, Diabetes, 55, 2974, 10.2337/db06-0690
Kamba, 2006, VEGF-dependent plasticity of fenestrated capillaries in the normal adult microvasculature, Am. J. Physiol. Heart Circ. Physiol., 290, H560, 10.1152/ajpheart.00133.2005
Shin, 2010, Sunitinib deregulates tumor adaptation to hypoxia by inhibiting HIF-1alpha synthesis in HT-29 colon cancer cells, Biochem. Biophys. Res. Commun., 398, 205, 10.1016/j.bbrc.2010.06.060
Aguirre, 2010, Cardiovascular effects in rats following exposure to a receptor tyrosine kinase inhibitor, Toxicol. Pathol., 38, 416, 10.1177/0192623310364027
Kawasaki, 1998, A family of cAMP-binding proteins that directly activate Rap1, Science, 282, 2275, 10.1126/science.282.5397.2275
Lochner, 2006, The many faces of H89: a review, Cardiovasc. Drug Rev., 24, 261, 10.1111/j.1527-3466.2006.00261.x
Cheng, 2008, Epac and PKA: a tale of two intracellular cAMP receptors, Acta Biochim. Biophys. Sin. Shanghai, 40, 651, 10.1111/j.1745-7270.2008.00438.x
Shen, 2012, IGF-1 receptor is down-regulated by sunitinib induces MDM2-dependent ubiquitination, FEBS Open Bio, 2, 1, 10.1016/j.fob.2011.12.001
Avram, 2008, IGF-1 protects against dexamethasone-induced cell death in insulin secreting INS-1 cells independent of AKT/PKB phosphorylation, Cell. Physiol. Biochem., 21, 455, 10.1159/000129638
Ullrich, 2014, IGF-1 and insulin-receptor signalling in insulin secreting cells: from function to survival, 659
Panse, 2015, Activation of extracellular signal-regulated protein kinases 1 and 2 (ERK1/2) by free fatty acid receptor 1 (FFAR1/GPR40) protects from palmitate-induced beta cell death, but plays no role in insulin secretion, Cell. Physiol. Biochem., 35, 1537, 10.1159/000373969
Ullrich, 1984, Islet cyclic AMP levels are not lowered during alpha 2-adrenergic inhibition of insulin release, J. Biol. Chem., 259, 4111, 10.1016/S0021-9258(17)43016-X
Nolan, 2006, Fatty acid signaling in the beta-cell and insulin secretion, Diabetes, 55, S16, 10.2337/db06-S003
Latour, 2007, GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo, Diabetes, 56, 1087, 10.2337/db06-1532
Wagner, 2013, Reevaluation of fatty acid receptor 1 as a drug target for the stimulation of insulin secretion in humans, Diabetes, 62, 2106, 10.2337/db12-1249
Ferdaoussi, 2012, G protein-coupled receptor (GPR)40-dependent potentiation of insulin secretion in mouse islets is mediated by protein kinase D1, Diabetologia, 55, 2682, 10.1007/s00125-012-2650-x
Schnell, 2007, Free fatty acids increase cytosolic free calcium and stimulate insulin secretion from beta-cells through activation of GPR40, Mol. Cell. Endocrinol., 263, 173, 10.1016/j.mce.2006.09.013
MacDonald, 2002, The multiple actions of GLP-1 on the process of glucose-stimulated insulin secretion, Diabetes, 51, S434, 10.2337/diabetes.51.2007.S434
Fehmann, 1995, The effects of glucagon-like peptide-I (GLP-I) on hormone secretion from isolated human pancreatic islets, Pancreas, 11, 196, 10.1097/00006676-199508000-00014
Kashima, 2001, Critical role of cAMP-GEFII--Rim2 complex in incretin-potentiated insulin secretion, J. Biol. Chem., 276, 46046, 10.1074/jbc.M108378200
Schwede, 2015, Rp-cAMPS prodrugs reveal the cAMP dependence of first-phase glucose-stimulated insulin secretion, Mol. Endocrinol., 29, 988, 10.1210/me.2014-1330
Meyer, 2011, PEST motif serine and tyrosine phosphorylation controls vascular endothelial growth factor receptor 2 stability and downregulation, Mol. Cell. Biol., 31, 2010, 10.1128/MCB.01006-10
Villalta, 2013, Inhibition of VEGFR-2 reverses type 1 diabetes in NOD mice by abrogating insulitis and restoring islet function, Diabetes, 62, 2870, 10.2337/db12-1619
Jewell, 2008, The tyrosine phosphorylation of Munc18c induces a switch in binding specificity from syntaxin 4 to Doc2beta, J. Biol. Chem., 283, 21734, 10.1074/jbc.M710445200
Bakke, 2013, Regulation of the SNARE-interacting protein Munc18c tyrosine phosphorylation in adipocytes by protein-tyrosine phosphatase 1B, Cell Commun. Signal, 11, 57, 10.1186/1478-811X-11-57
Hennige, 2003, Upregulation of insulin receptor substrate-2 in pancreatic beta cells prevents diabetes, J. Clin. Invest., 112, 1521, 10.1172/JCI18581
Hagerkvist, 2007, Amelioration of diabetes by imatinib mesylate (Gleevec): role of beta-cell NF-kappaB activation and anti-apoptotic preconditioning, FASEB J., 21, 618, 10.1096/fj.06-6910com
Mokhtari, 2011, Effects of Imatinib Mesylate (Gleevec) on human islet NF-kappaB activation and chemokine production in vitro, PLoS One, 6, 10.1371/journal.pone.0024831
Hagerkvist, 2006, Imatinib mesylate (Gleevec) protects against streptozotocin-induced diabetes and islet cell death in vitro, Cell Biol. Int., 30, 1013, 10.1016/j.cellbi.2006.08.006
Sanchez, 2013, Sunitinib enhances neuronal survival in vitro via NF-kappaB-mediated signaling and expression of cyclooxygenase-2 and inducible nitric oxide synthase, J. Neuroinflammation, 10, 93, 10.1186/1742-2094-10-93
Krishnamurthy, 2007, Wang R: c-Kit in early onset of diabetes: a morphological and functional analysis of pancreatic beta-cells in c-KitW-v mutant mice, Endocrinology, 148, 5520, 10.1210/en.2007-0387
Rainer, 2012, Sunitinib causes dose-dependent negative functional effects on myocardium and cardiomyocytes, BJU Int., 110, 1455, 10.1111/j.1464-410X.2012.11134.x
Mooney, 2015, Effects of acute and chronic sunitinib treatment on cardiac function and calcium/calmodulin-dependent protein kinase II, Br. J. Pharmacol., 10
