Sulphur mustard induces progressive toxicity and demyelination in brain cell aggregate culture

NeuroToxicology - Tập 84 - Trang 114-124 - 2021
Thomas W. Sawyer1, Yushan Wang1, Yanfeng Song1, Mercy Villanueva1, Andres Jimenez1
1Defence Research & Development Canada, Suffield Research Centre, Box 4000, Medicine Hat, Alberta T1A 8K6, Canada

Tài liệu tham khảo

Anslow, 1946, Systemic pharmacology and pathology of sulfur and nitrogen mustards Anslow, 1948, The intravenous, subcutaneous and cutaneous toxicity of bis (2-chloroethyl) sulphide (mustard gas) and of various derivatives, J. Pharmacol. Exp. Ther., 93, 1 Arroyo, 2000, Response of normal human keratinocytes to sulfur mustard: cytokine release, J. Appl. Toxicol., 20, S63, 10.1002/1099-1263(200012)20:1+<::AID-JAT687>3.0.CO;2-B Azarpazhooh, 2007, Can mustard gas induce late onset polyneuropathy?, Med. J. Islamic Rep. Iran, 21, 145 Balali-Mood, 2005, The pharmacology, toxicology and medical treatment of sulphur mustard poisoning, Fund. Clin. Pharmacol, 19, 297, 10.1111/j.1472-8206.2005.00325.x Balali-Mood, 2008, Chronic health effects of sulphur mustard exposure with special reference to Iranian veterans, Emerging Hlth. Threats J, 1, 7068, 10.3402/ehtj.v1i0.7068 Batal, 2014, DNA damage in internal organs after cutaneous exposure to sulphur mustard, Toxicol. Appl. Pharmacol., 278, 39, 10.1016/j.taap.2014.04.003 Batal, 2015, A guanine-ethylthioethyl-glutathione adduct as a major DNA lesion in the skin and in organs of mice exposed to sulfur mustard, Toxicol. Lett., 233, 1, 10.1016/j.toxlet.2015.01.001 Boursnell, 1946, Studies on mustard gas (ββ’-dichlorodiethyl sulphide) and some related compounds. 5. The fate of injected mustard gas (containing radioactive sulphur) in the animal body, Biochem. J., 40, 756, 10.1042/bj0400756 Boursnell, 1946, Studies on mustard gas (ββ’-dichlorodiethyl sulphide) and some related compounds. 6. The fate of injected ββ’dichlorodiethyl sulphoxide (containing radioactive sulphur) in the animal body, Biochem. J., 40, 765, 10.1042/bj0400765 Brandolini, 2017, CXCR1/2 pathways in paclitaxel-induced neuropathic pain, Oncotarget, 8, 23188, 10.18632/oncotarget.15533 Brandolini, 2019, Chemokine signaling in chemotherapy-induced neuropathic pain, Internat. J. Molec. Sci., 2019, 2904, 10.3390/ijms20122904 Chan, 2013, Detection of necrosis by release of lactate dehydrogenase (LDH) activity, Methods Mol. Biol., 979, 65, 10.1007/978-1-62703-290-2_7 Choi, 2018, Activated T cells induce proliferation of oligodendrocyte progenitor cells via release of vascular endothelial cell grow factor-A, Glia, 66, 2503, 10.1002/glia.23501 Chong, 2005, Activating Akt and the brain’s resources to drive cellular survival and prevent inflammatory injury, Histol. Histopathol., 20, 299 Cullumbine, 1948, Factors influencing the penetration of the skin by chemical agents, Quart. J. Exp. Physiol. Cogn. Med. Sci., 34, 83 Dacre, 1996, Toxicology and pharmacology of the chemical warfare agent sulfur mustard, Pharmacol. Rev., 48, 289 Darchini-Maragheh, 2012, Delayed neurological complications of sulphur mustard and tabun poisoning in 43 Iranian veterans, Basic Clin. Pharmacol. Toxicol., 111, 426, 10.1111/j.1742-7843.2012.00922.x De Almodovar, 2009, Role and therapeutic potential of VEGF in the nervous system, Physiol. Rev., 89, 607, 10.1152/physrev.00031.2008 Di Penta, 2013, Oxidative stress and proinflammatory cytokines contribute to demyelination and axonal damage in a cerebellar culture model of neuroinflammation, PLoS One, 8, 10.1371/journal.pone.0054722 Diaz-Arrastia, 2014, Acute biomarkers of traumatic brain injury: relationship between plasma levels of ubiquitin C-terminal hydrolase-L1 and glial fibrillary acidic protein, J. Neurotrauma, 31, 19, 10.1089/neu.2013.3040 Drasch, 1987, Concentrations of mustard gas [bis(2-chloroethyl)sulfide] in the tissues of a victim of a vesicant exposure, J. Forensic Sci., 32, 1788, 10.1520/JFS11235J Dube, 1998, Dose response of sulphur mustard: behavioral and toxic signs in rats, Indian J. Physiol. Pharmacol., 42, 389 Eisenmenger, 1991, Clinical and morphological findings on mustard gas [bis(2-chloroethyl)sulfide] poisoning, J. Forensic Sci., 36, 1688, 10.1520/JFS13192J Elsayed, 1989, Response of mouse brain to a single subcutaneous injection of the monofunctional sulfur mustard, butyl 2-chloroethyl sulfide (BCS), Toxicology, 58, 11, 10.1016/0300-483X(89)90100-5 Evison, 2002, Chemical weapons, Brit. J. Med, 324, 332, 10.1136/bmj.324.7333.332 Gadsden-Gray, 2012, Induction of neuronal damage in guinea pig brain by intratracheal infusion of 2-chloroethyl ethyl sulfide, a mustard gas analog, J. Biochem. Mol. Toxicol., 26, 23, 10.1002/jbt.20409 Gao, 2010, Chemokines, neuronal-glial interactions, and central processing of neuropathic pain, Pharmacol. Therapeut, 126, 56, 10.1016/j.pharmthera.2010.01.002 Gawronski, 2004, Microtiter assay for glutamine synthetase biosynthetic activity using inorganic phosphate detection, Anal. Biochem., 327, 114, 10.1016/j.ab.2003.12.024 Gilchrist, 1926, Chapter VIII. 1. Statistical considerations of gas casualties Gilman, 1946, The biological actions and therapeutic applications of the B-chloroethyl amines and sulfides, Science, 103, 436 Graef, 1948, The clinical and pathologic effects of the nitrogen and sulfur mustards in laboratory animals, Am. J. Pathol., 25, 1 Gros-Désormeaux, 2018, Cognitive and emotional impairments after cutaneous intoxication by CEES (a sulfur mustard analog) in mice, Toxicol. Lett., 293, 73, 10.1016/j.toxlet.2017.07.889 Hashemian, 2006, Anxiety, depression, and posttraumatic stress in Iranian survivors of chemical warfare, J. Am. Med. Assoc., 296, 560, 10.1001/jama.296.5.560 Hilmas, 2008, History of chemical warfare Hiratsuka, 2019, VEFG- and PDGF-dependent proliferation of oligodendrocyte progenitor cells in medulla oblongata after LPC-induced focal demyelination, J. Neuroimmunol., 332, 176, 10.1016/j.jneuroim.2019.04.016 Höftberger, 2018, Inflammatory demyelinating diseases of the central nervous system, 10.1016/B978-0-12-802395-2.00019-5 Holisaz, 2006, Peripheral neuropathy in chemical warfare victims, Internet J. Rescue Disaster, 6, 1 Holisaz, 2007, Screening for peripheral neuropathy in chemical warfare victims, Int. J. Rehabil. Res., 30, 71, 10.1097/MRR.0b013e3280143c49 Honda, 2010, Serum glial fibrillary acidic protein is a highly specific biomarker for traumatic brain injury in humans compared to S-100B and neuron-specific enolase, J. Trauma, 69, 104 Honegger, 2003, Aggregating neural cell cultures Honegger, 2011, Preparation, maintenance, and use of serum-free aggregating brain cell cultures, Vol. 758 Horowitz, 2018, Differential expression of corneal and limbal cytokines and chemokines throughout the clinical course of sulfur mustard induced ocular injury in the rabbit model, Exp. Eye Res., 177, 145, 10.1016/j.exer.2018.08.008 Hurst, 2001, Chronic effects of acute low-level exposure to the chemical warfare agent sulfur mustard Husain, 1996, Effect of topically applied sulphur mustard on antioxidant enzymes in blood cells and body tissues of rats, J. Appl. Toxicol., 16, 245, 10.1002/(SICI)1099-1263(199605)16:3<245::AID-JAT339>3.0.CO;2-3 Jaferi, 2007, Dose- and time-dependent effects of sulfur mustard on antioxidant system in liver and brain of rat, Toxicology, 231, 30, 10.1016/j.tox.2006.11.048 Karnofsky, 1948, Studies on the mechanism of action of the nitrogen and sulfur mustards in vivo, Am. J. Pharmacol, 24, 275 Kehe, 2005, Medical aspects of sulphur mustard poisoning, Toxicology, 214, 198, 10.1016/j.tox.2005.06.014 Kehe, 2009, Molecular toxicology of sulphur mustard-induced cutaneous inflammation and blistering, Toxicology, 263, 12, 10.1016/j.tox.2009.01.019 Khateri, 2015, Mental health status following severe sulfur mustard exposure: a long-term study of Iranian war survivors, Asia-Pacific Psych, 9 Klain, 1988, Skin penetration and tissue distribution of [14C]butyl 2-chloroethyl sulfide in the rat, J. Toxicol. Cutan. Ocular Toxicol., 7, 255, 10.3109/15569528809056305 Lynch, 1918, On dichloroethylsulphide (mustard gas). I. The systemic effects and mechanism of action, J. Pharmacol. Exp. Therapeut, 12, 265 Marshall, 1926, Chapter XII. Physiological action of dichloroethyl sulphide (mustard gas) Mishra, 2012, Inhalation of sulfur mustard causes long-term T cell-dependent inflammation: possible role of Th17 cells in chronic lung pathology, Internat. Immunopharmacol., 13, 101, 10.1016/j.intimp.2012.03.010 Moraes, 2020, Participation of CXCL1 in glial cells during neuropathic pain, Eur. J. Pharmacol., 875, 10.1016/j.ejphar.2020.173039 O’Sullivan, 2017, Demyelination induced by oxidative stress is regulated by sphingosine 1-phosphate receptors, Glia, 2017, 1 Ohno, 2019, Axonal and neuronal degeneration in myelin diseases, Neuroscience Res, 139, 48, 10.1016/j.neures.2018.08.013 Papirmeister, 1991 Pechura, 1993 Petzold, 2005, Neurofilament phosphoforms: surrogate markers for axonal injury, degeneration and loss, J. Neurol. Sci., 233, 183, 10.1016/j.jns.2005.03.015 Petzold, 2011, In vivo monitoring of neuronal loss in traumatic brain injury: a microdialysis study, Brain, 134, 464, 10.1093/brain/awq360 Rai, 2019, The role of PI3K/Akt and ERK in neurodegenerative disorders, Neurotox. Res., 35, 775, 10.1007/s12640-019-0003-y Razavi, 2012, A review on delayed toxic effects of sulfur mustard in Iranian veterans, DARU J. Pharmaceut. Sci. Razavi, 2014, Sulfur mustard effects on mental health and quality-of-life: a review, Iran J. Psychiat. Behav. Sci, 8, 11 Renshaw, 1946, Mechanisms in production of cutaneous injuries by sulfur and nitrogen mustards Roshan, 2013, Long-term effects of sulfur mustard on civilians’ mental health 20 years after exposure (the Sardasht-Iran Cohort Study), Health Qual. Life Outcomes, 11, 69, 10.1186/1477-7525-11-69 Ruff, 2007, Signaling molecules in sulfur mustard-induced cutaneous injury, Eplasty, 27 Sa Santos, 2007, Stirred vessel cultures of rat brain cell aggregates: characterization of major metabolic pathways and cell population dynamics, J. Neurosci. Res., 85, 3386, 10.1002/jnr.21409 Sanchez, 2010, Multiple neurotrophic effects of VEGF on cultured neurons, Neuropeptides, 44, 323, 10.1016/j.npep.2010.04.002 Sauvaigo, 2016, Impact of topical application of sulfur mustard on mice skin and distant organs DNA repair enzyme signature, Toxicol. Lett., 241, 71, 10.1016/j.toxlet.2015.11.001 Sawyer, 2018, Primary blast causes delayed effects without cell death in shell-encased brain cell aggregates, J. Neurotrauma, 35, 174, 10.1089/neu.2016.4961 Shakarjian, 2010, Mechanisms mediating the vesicant actions of sulfur mustard after cutaneous exposure, Toxicol. Sci., 114, 5, 10.1093/toxsci/kfp253 Sharma, 2009, Neurobehavioral impairments, generation of oxidative stress and release of pro-oxidative factors after chronic exposure to sulphur mustard in mouse brain, Toxicol. Appl. Pharmacol., 240, 208, 10.1016/j.taap.2009.06.015 Sidell, 1997, Long-term effects of nerve agents and vesicants, 229 Sidell, 1997, Vesicants, 197 Silva, 2017, CXCL1/CXCR2 signaling in pathological pain. Role in peripheral and central sensitization, Neurobiol. Disease, 105, 109, 10.1016/j.nbd.2017.06.001 Sinclair, 1948, The clinical features of mustard-gas poisoning in man, Br. Med. J., 2, 290, 10.1136/bmj.2.4570.290 Singh, 2018, Therapeutic journey of nitrogen mustard as alkylating anticancer agents: historic to future perspectives, Eur. J. Med. Chem., 151, 401, 10.1016/j.ejmech.2018.04.001 Smith, 2002, Vesicant agents and antivesicant medical countermeasures: clinical toxicology and psychological implications, Mil. Psych., 14, 145, 10.1207/S15327876MP1402_5 Smith, 1991, Medical defence against blistering chemical warfare agents, Arch. Dermatol., 127, 1207, 10.1001/archderm.1991.01680070107017 Smith, 1999, Demyelination: the role of reactive oxygen and nitrogen species, Brain Pathol., 9, 69, 10.1111/j.1750-3639.1999.tb00212.x Szinicz, 2005, History of chemical and biological warfare agents, Toxicology, 214, 167, 10.1016/j.tox.2005.06.011 Talabani, 2018, Long-term health effects of chemical warfare agents on children following a single heavy exposure, Hum. Exp. Toxicol., 37, 836, 10.1177/0960327117734620 Thomsen, 1998, Chronic neuropathic symptoms after exposure to mustard gas: a long-term investigation, J. Am. Acad. Dermatol., 39, 187, 10.1016/S0190-9622(98)70072-6 Vedder, 1925 Verheyen, 2012, Systemic anti-vascular endothelial growth factor therapies induce a painful sensory neuropathy, Brain, 135, 2629, 10.1093/brain/aws145 Verheyen, 2013, Therapeutic potential of VEGF and VEGF-derived peptide in peripheral neuropathies, Neuroscience, 244, 77, 10.1016/j.neuroscience.2013.03.050 Warthin, 1926, Pathologic action of mustard gas (dichloroethylsulphide) Warthin, 1918, The pathology of skin lesions produced by mustard gas, J. Lab. Clin. Med., iii, 447 Warthin, 1919 Willems, 1989, Clinical management of mustard gas casualties, Annales Medicinae Militaris Belgicae, 3, 1 Yuan, 2012, Neurofilaments at a glance, J. Cell. Sci., 125, 3257, 10.1242/jcs.104729 Yue, 2015, Distribution of DNA adducts and corresponding tissue damage of Sprague-Dawley rats with percutaneous exposure to sulfur mustard, Chem. Res. Toxicol., 28, 532, 10.1021/tx5004886 Zhou, 2020, The therapeutic potential of chemokines in the treatment of chemotherapy-induced peripheral neuropathy, Curr. Drug Targets, 21, 288, 10.2174/1389450120666190906153652