Suicidal insulin overdose in a Type 1 diabetic patient: relation of serum insulin concentrations to the duration of hypoglycemia

Arem, 1985, Insulin overdose in eight patients: insulin pharmacokinetics and review of the literature, Medicine, 64, 323, 10.1097/00005792-198509000-00004 Gavin, 1974, Insulin-dependent regulation of insulin receptor concentrations: a direct demonstration in cell culture, Proc Natl Acad Sci USA, 71, 84, 10.1073/pnas.71.1.84 Henry, 1978, Defective absorption of injected insulin, Lancet, II, 741, 10.1016/S0140-6736(78)92746-0 Jefferys, 1983, Self poisoning in diabetic patients, Hum Toxicol, 2, 345, 10.1177/096032718300200228 Lauritzen, 1982, Absorption of isophane (NPH) insulin and its clinical implications, Br Med J, 285, 159, 10.1136/bmj.285.6336.159 Lindgren, 1960, Enormous dose of insulin with suicidal intent, Acta Med Scand, 167, 297, 10.1111/j.0954-6820.1960.tb03550.x Martin, 1977, Attempted suicide by insulin overdose in insulin-requiring diabetics, Med J Aust, 1, 58, 10.5694/j.1326-5377.1977.tb130503.x Olefsky, 1981, Mechanisms of insulin resistance in obesity and noninsulin-dependent (Type II) diabetes, Am J Med, 70, 151, 10.1016/0002-9343(81)90422-8 Page, 1974, Treatment of diabetic coma with continuous low-dose infusion of insulin, Br Med J, 29, 687, 10.1136/bmj.2.5921.687 Roy, 1980, Time-action characteristics of regular and NPH insulin in insulin-treated diabetics, J Clin Endocrinol Metab, 50, 475, 10.1210/jcem-50-3-475 Rubenstein, 1968, Role of the kidney in insulin metabolism and excretion, Diabetes, 17, 161, 10.2337/diab.17.3.161 Van Haeften, 1986, Effect of insulin antibodies and their kinetic characteristic on plasma free insulin dynamics in patients with diabetes mellitus, Metabolism, 35, 649, 10.1016/0026-0495(86)90173-3 Woodworth, 1994, Establishment of time-action profiles for regular and NPH insulin using pharmacodynamic modeling, Diabetes Care, 17, 64, 10.2337/diacare.17.1.64 Woodworth, 1994, Comparative pharmacokinetics and glucodynamics of two human insulin mixtures, Diabetes Care, 17, 366, 10.2337/diacare.17.5.366