Sudden death due to biventricular non-compaction cardiomyopathy in a 14-year-old

Springer Science and Business Media LLC - 2014
Paul J. Cohen1, Joseph A. Prahlow2
1Indiana University School of Medicine-Indianapolis, Indianapolis, USA
2The Medical Foundation, and Indiana University School of Medicine-South Bend, South Bend, USA

Tóm tắt

A 14-year-old African-American female with a long-standing medically and ablation-treated history of tachycardia with associated seizures died suddenly. Upon autopsy, evidence of gross non-compaction involving the left ventricle, as well as possible subtle non-compaction of the right ventricle was discovered. Microscopically, there was focal myocyte hypertrophy as well as myxoid connective tissue and subendocardial fibroelastosis in the areas affected by the non-compaction. Arrhythmia, precipitated by the underlying cardiomyopathy, led to this young girl’s death. Non-compaction cardiomyopathy is a rare cardiac disorder which commonly goes undiagnosed until post-mortem, although diagnosis through echocardiogram, CT, or MRI is possible and there is criterion for diagnosis with each of these.

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