Successful Treatment of Paecilomyces variotii Peritonitis in a Liver Transplant Patient

Mycopathologia et mycologia applicata - 2014
Meltem Polat1, Soner Sertan Kara1, Anıl Tapısız1, Zeliha Demirtaş2, Sinan Sarı2, Ayşe Kalkancı3, Hasan Tezer1, Buket Dalgıç2
1Department of Pediatric Infectious Diseases, Gazi University School of Medicine, Beşevler, Ankara, Turkey
2Department of Pediatric Gastroenterology, Gazi University, School of Medicine, Ankara, Turkey
3Department of Microbiology, Gazi University, School of Medicine, Ankara, Turkey

Tóm tắt

Paecilomyces variotii has previously been reported as a causative pathogen for peritonitis in patients on continuous ambulatory peritoneal dialysis and shown to be usually sensitive to amphotericin B and resistant to voriconazole. We report the first case, to our knowledge, of P. variotii peritonitis in a liver transplant patient, which was unresponsive to initial liposomal amphotericin B (L-AmB) treatment and resolved dramatically after the addition of voriconazole. The present case provides evidence for the clinical and microbiological effectiveness of voriconazole combined with L-AmB in treating P. variotii peritonitis refractory to initial L-AmB treatment.

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Tài liệu tham khảo

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Mycopathologia et mycologia applicata

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