Substrate-Dependent Ligand Inhibition of the Human Organic Cation Transporter OCT2
Tóm tắt
Từ khóa
Tài liệu tham khảo
Bednarczyk, 2000, NBD-TMA: a novel fluorescent substrate of the peritubular organic cation transporter of renal proximal tubules, Pflugers Arch, 440, 184, 10.1007/s004240000283
Groves, 1994, Peritubular organic cation transport in isolated rabbit proximal tubules, Am J Physiol, 266, F450
Lin, 1991, Time-resolved fluorescence of nitrobenzoxadiazole-aminohexanoic acid: effect of intermolecular hydrogen-bonding on non-radiative decay, Photochem Photobiol, 54, 361, 10.1111/j.1751-1097.1991.tb02028.x
Moaddel, 2007, Pharmacophore modelling of stereoselective binding to the human organic cation transporter (hOCT1), Br J Pharmacol, 151, 1305, 10.1038/sj.bjp.0707341
Motohashi, 2002, Gene expression levels and immunolocalization of organic ion transporters in the human kidney, J Am Soc Nephrol, 13, 866, 10.1681/ASN.V134866
Schumacher, 2003, Deciphering the molecular basis of multidrug recognition: crystal structures of the Staphylococcus aureus multidrug binding transcription regulator QacR, Res Microbiol, 154, 69, 10.1016/S0923-2508(02)00013-X
Segel IH (1975) Enzyme Kinetics, pp 100–135, John Wiley & Sons, New York.
Sissung, 2012, Transporter pharmacogenetics: transporter polymorphisms affect normal physiology, diseases, and pharmacotherapy, Discov Med, 13, 19
Thummel KE Shen DD (2001) Design and optimization of dosage regimens: pharmacokinetic data, in Goodman & Gilman’s: The Pharmacological Basis of Therapeutics ( Hardman JG Limbird LE , eds, ed) pp 1917–2023, McGraw-Hill, New York.